PUMA sensitizes lung cancer cells to chemotherapeutic agents and irradiation
about
PUMA, a potent killer with or without p53Sp1 and p73 activate PUMA following serum starvationTumor suppressor genes and their underlying interactions in paclitaxel resistance in cancer therapySmac modulates chemosensitivity in head and neck cancer cells through the mitochondrial apoptotic pathwayAurora kinase inhibition induces PUMA via NF-κB to kill colon cancer cells.PUMA decreases the growth of prostate cancer PC-3 cells independent of p53.The role of ROS and subsequent DNA-damage response in PUMA-induced apoptosis of ovarian cancer cells.BH3-based fusion artificial peptide induces apoptosis and targets human colon cancer.Regorafenib inhibits colorectal tumor growth through PUMA-mediated apoptosis.PUMA mediates EGFR tyrosine kinase inhibitor-induced apoptosis in head and neck cancer cellsThe multi-targeted kinase inhibitor sunitinib induces apoptosis in colon cancer cells via PUMA.RNA interference targeting slug increases cholangiocarcinoma cell sensitivity to cisplatin via upregulating PUMAHER2 phosphorylates and destabilizes pro-apoptotic PUMA, leading to antagonized apoptosis in cancer cellsNovel cytotoxic vectors based on adeno-associated virus.PUMA-mediated apoptosis drives chemical hepatocarcinogenesis in mice.p53 upregulated modulator of apoptosis sensitizes drug-resistant U251 glioblastoma stem cells to temozolomide through enhanced apoptosisThe nuclear function of p53 is required for PUMA-mediated apoptosis induced by DNA damage.Inhibition of AKT2 enhances sensitivity to gemcitabine via regulating PUMA and NF-κB signaling pathway in human pancreatic ductal adenocarcinoma.The p53 upregulated modulator of apoptosis (PUMA) chemosensitizes intrinsically resistant ovarian cancer cells to cisplatin by lowering the threshold set by Bcl-x(L) and Mcl-1Inhibiting oncogenic signaling by sorafenib activates PUMA via GSK3β and NF-κB to suppress tumor cell growthmTOR inhibitors induce apoptosis in colon cancer cells via CHOP-dependent DR5 induction on 4E-BP1 dephosphorylation.Chemical perturbation of Mcl-1 pre-mRNA splicing to induce apoptosis in cancer cells.Multimodal interaction with BCL-2 family proteins underlies the proapoptotic activity of PUMA BH3PUMA promotes Bax translocation by both directly interacting with Bax and by competitive binding to Bcl-X L during UV-induced apoptosis.BRAFV600E-dependent Mcl-1 stabilization leads to everolimus resistance in colon cancer cellsEZH2-mediated Puma gene repression regulates non-small cell lung cancer cell proliferation and cisplatin-induced apoptosis.Idelalisib induces PUMA-dependent apoptosis in colon cancer cells.Co-targeting translation and proteasome rapidly kills colon cancer cells with mutant RAS/RAF via ER stress.MicroRNAs in lung cancer.The Evaluation and Comparison of Transcriptionally Targeted Noxa and Puma Killer Genes to Initiate Apoptosis Under Cancer-Specific Promoter CXCR1 in Hepatocarcinoma Gene TherapyGene therapy of pancreatic cancer targeting the K-Ras oncogene.A feasibility study on gene therapy of pancreatic carcinoma with Ad-PUMA.Development of small-molecule PUMA inhibitors for mitigating radiation-induced cell death.Slug inhibition upregulates radiation-induced PUMA activity leading to apoptosis in cholangiocarcinomas.PUMA suppresses intestinal tumorigenesis in mice.Synergistic Effect of Expressed miR-128 and Puma Protein on Targeted Induction of Tumor Cell ApoptosisNSAIDs downregulate Bcl-X(L) and dissociate BAX and Bcl-X(L) to induce apoptosis in colon cancer cells.PUMA Kills Stem Cells to Stall Cancer?Inhibitory effect of p53 upregulated modulator of apoptosis targeting siRNA on hypoxia/reoxygenation-induced cardiomyocyte apoptosis in rats.Expressions of p53 and PUMA in fibroblasts of systemic sclerosis patients are normal at transcription level.
P2860
Q24631776-A9FA4685-8A8C-433E-BFA4-3C5B7681AD06Q24655353-98003AA2-F9FC-4437-B9D7-08B9416715BFQ26768521-45C4C091-BB95-4023-A6AB-7661D6023B2CQ28303498-AAD4ED32-E90A-4851-A4FE-D6C0A4735CA4Q33579079-B7EC9479-FE23-4CCF-A9DD-55C5426C034BQ33597750-48D53112-34F0-46E8-80E5-B7D8BA1F0470Q33618734-93E63471-DE23-4922-A396-88B206E82690Q33713980-3865CB51-5F71-416B-A65F-ED078B35452CQ33838524-2249CB0D-86CF-4CB6-B879-900F6BFEA45FQ33857728-0AEAF125-4823-4FD6-97B4-632BE5FA4307Q34389359-296DEFB7-16D3-4CE6-8B1E-FE7F0EEE766EQ34578107-4A867FAC-C017-43E3-B3DD-E60BCB6B0B18Q35043596-4F55384C-BF91-4EA5-BF33-FF3CA9867F24Q35155679-AE47D1A2-45CC-4011-9248-684C717A683AQ35249314-6ECB3A39-F627-4EF4-A402-61F8D0AE6795Q35387486-E34294A1-8CAB-47B9-83D2-EDF17852F7BEQ35676779-26EC75F6-B1F9-4AE6-9754-4838619E427DQ35719620-AAC77FA4-8C72-4C9C-8002-06774A8F1385Q35876786-01A8CC74-DAFC-406D-B1E3-981B79E2A662Q35928707-6F11271D-2707-4514-BB3E-A16076A095FAQ36156993-1509704B-543A-4F55-881B-ACB1F38CDEC7Q36853190-449A666F-1903-458A-B70A-1B68017C6B9BQ37192687-82C4FE18-1849-4DF5-A18E-F80217E96548Q37246322-64517F4B-6CEC-4301-A7B8-7E3351872B4DQ37565246-F359F22C-6CF8-4317-AF09-2C83DC915D23Q37636628-5442977D-5A11-4E94-8367-6BFEFC506EA7Q37701548-0CCFE14B-00DB-4F54-9F42-B9514FCE8DECQ37705955-8A080745-5D1E-4A06-BDEF-8A983946322CQ38261676-2E2A0191-5EEE-4E99-BDF5-4D27830D0AA5Q38729185-4CA4FA39-55A9-4A65-A8AC-F42500D8A59CQ39253164-E4B100A4-1BA9-438E-BC7F-C4A1707FBB90Q39344111-887E16C0-BD5D-43B8-97FA-DAA4C10286E8Q39592538-451CB85C-C4A8-421F-8E1E-F965CB74C3CCQ39625434-DB3FEFA7-F43A-48E2-B7F0-7953123865A8Q40620684-0EE57F42-0433-45FB-8FD6-3FD3CDD6727AQ41674108-E0D51C6F-96BB-40B0-8CC0-4176E7C298FEQ42444746-65E82E4F-BE1B-4133-AE22-DA7413225801Q42944759-9A645D1C-5057-4629-B2BD-4673625B2A4CQ45880216-3DDC3C00-E82E-409B-A0FF-6E15BD0193AEQ48348597-9BCC0CAE-00D4-4848-9465-F0115E9C00DF
P2860
PUMA sensitizes lung cancer cells to chemotherapeutic agents and irradiation
description
2006 nî lūn-bûn
@nan
2006 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
PUMA sensitizes lung cancer cells to chemotherapeutic agents and irradiation
@ast
PUMA sensitizes lung cancer cells to chemotherapeutic agents and irradiation
@en
PUMA sensitizes lung cancer cells to chemotherapeutic agents and irradiation
@nl
type
label
PUMA sensitizes lung cancer cells to chemotherapeutic agents and irradiation
@ast
PUMA sensitizes lung cancer cells to chemotherapeutic agents and irradiation
@en
PUMA sensitizes lung cancer cells to chemotherapeutic agents and irradiation
@nl
prefLabel
PUMA sensitizes lung cancer cells to chemotherapeutic agents and irradiation
@ast
PUMA sensitizes lung cancer cells to chemotherapeutic agents and irradiation
@en
PUMA sensitizes lung cancer cells to chemotherapeutic agents and irradiation
@nl
P2093
P3181
P1476
PUMA sensitizes lung cancer cells to chemotherapeutic agents and irradiation
@en
P2093
P304
P3181
P356
10.1158/1078-0432.CCR-05-2429
P407
P577
2006-05-01T00:00:00Z