Gadd45 beta mediates the NF-kappa B suppression of JNK signalling by targeting MKK7/JNKK2 - Wikidata - wikimedia - TriplyDB

Gadd45 beta mediates the NF-kappa B suppression of JNK signalling by targeting MKK7/JNKK2

Gadd45 beta mediates the NF-kappa B suppression of JNK signalling by targeting MKK7/JNKK2

http://www.wikidata.org/entity/Q28240600

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From death receptor to reactive oxygen species and c-Jun N-terminal protein kinase: the receptor-interacting protein 1 odyssey Cancer-selective targeting of the NF-κB survival pathway with GADD45β/MKK7 inhibitors An antiapoptotic protein, c-FLIPL, directly binds to MKK7 and inhibits the JNK pathway JAMP, a Jun N-terminal kinase 1 (JNK1)-associated membrane protein, regulates duration of JNK activity.Gadd45 in the response of hematopoietic cells to genotoxic stress Gadd45 stress sensors in malignancy and leukemia Genetic deletion of Gadd45b, a regulator of active DNA demethylation, enhances long-term memory and synaptic plasticity GADD45 proteins: central players in tumorigenesis Elevated NF-kappaB responses and FLIP levels in leukemic but not normal lymphocytes: reduction by salicylate allows TNF-induced apoptosis Targeting xenobiotic receptors PXR and CAR in human diseases New molecular insights into peripheral T cell lymphomas Programmed necrosis in the cross talk of cell death and inflammation Crystal structure of human Gadd45γ [corrected] reveals an active dimer Wiring the cell signaling circuitry by the NF-kappa B and JNK1 crosstalk and its applications in human diseases Molecular mechanisms of liver injury and hepatocarcinogenesis: focusing on the role of stress-activated MAPK Gadd45 proteins as critical signal transducers linking NF-kappaB to MAPK cascades FADD regulates NF-κB activation and promotes ubiquitination of cFLIPL to induce apoptosis Nrf2 protects against 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-induced oxidative injury and steatohepatitis NF-kappaB functions as a tumour promoter in inflammation-associated cancer Noise-induced changes in gene expression in the cochleae of mice differing in their susceptibility to noise damage NF-kappaB is required for survival of immature auditory hair cells in vitro Gadd45 proteins induce G2/M arrest and modulate apoptosis in kidney cells exposed to hyperosmotic stress.NF-kappaB and not the MAPK signaling pathway regulates GADD45beta expression during acute inflammation.Visualization of AP-1 NF-kappaB ternary complexes in living cells by using a BiFC-based FRET.Differential expression of GADD45beta in normal and osteoarthritic cartilage: potential role in homeostasis of articular chondrocytes.Heterogeneous in vitro effects of doxorubicin on gene expression in primary human liposarcoma cultures Identification of Spt5 target genes in zebrafish development reveals its dual activity in vivo.Nuclear receptor CAR represses TNFalpha-induced cell death by interacting with the anti-apoptotic GADD45B Co-inhibition of NF-κB and JNK is synergistic in TNF-expressing human AML.GADD45beta enhances Col10a1 transcription via the MTK1/MKK3/6/p38 axis and activation of C/EBPbeta-TAD4 in terminally differentiating chondrocytes Gadd45beta deficiency in rheumatoid arthritis: enhanced synovitis through JNK signaling.ZIC1 is downregulated through promoter hypermethylation, and functions as a tumor suppressor gene in colorectal cancer NF-κB-to-AP-1 switch: a mechanism regulating transition from endothelial barrier injury to repair in endotoxemic mice.Expression profiling after activation of amino acid deprivation response in HepG2 human hepatoma cells Modeling the TNFα-induced apoptosis pathway in hepatocytes.Proteomic analysis of pathways involved in estrogen-induced growth and apoptosis of breast cancer cells.The cytoprotective effects of tumor necrosis factor are conveyed through tumor necrosis factor receptor-associated factor 2 in the heart.Co-activation of ERK, NF-kappaB, and GADD45beta in response to ionizing radiation.IKK/NF-kappaB signaling: balancing life and death--a new approach to cancer therapy.Gadd45b mediates Fas-induced apoptosis by enhancing the interaction between p38 and retinoblastoma tumor suppressor

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P2860

Gadd45 beta mediates the NF-kappa B suppression of JNK signalling by targeting MKK7/JNKK2

http://www.wikidata.org/entity/Q28240600

description

2004 nî lūn-bûn

@nan

2004 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2004 թվականի փետրվարին հրատարակված գիտական հոդված

@hy

2004年の論文

@ja

2004年論文

@yue

2004年論文

@zh-hant

2004年論文

@zh-hk

2004年論文

@zh-mo

2004年論文

@zh-tw

2004年论文

@wuu

name

Gadd45 beta mediates the NF-kappa B suppression of JNK signalling by targeting MKK7/JNKK2

@ast

Gadd45 beta mediates the NF-kappa B suppression of JNK signalling by targeting MKK7/JNKK2

@en

Gadd45 beta mediates the NF-kappa B suppression of JNK signalling by targeting MKK7/JNKK2

@en-gb

Gadd45 beta mediates the NF-kappa B suppression of JNK signalling by targeting MKK7/JNKK2

@nl

type

label

Gadd45 beta mediates the NF-kappa B suppression of JNK signalling by targeting MKK7/JNKK2

@ast

Gadd45 beta mediates the NF-kappa B suppression of JNK signalling by targeting MKK7/JNKK2

@en

Gadd45 beta mediates the NF-kappa B suppression of JNK signalling by targeting MKK7/JNKK2

@en-gb

Gadd45 beta mediates the NF-kappa B suppression of JNK signalling by targeting MKK7/JNKK2

@nl

prefLabel

Gadd45 beta mediates the NF-kappa B suppression of JNK signalling by targeting MKK7/JNKK2

@ast

Gadd45 beta mediates the NF-kappa B suppression of JNK signalling by targeting MKK7/JNKK2

@en

Gadd45 beta mediates the NF-kappa B suppression of JNK signalling by targeting MKK7/JNKK2

@en-gb

Gadd45 beta mediates the NF-kappa B suppression of JNK signalling by targeting MKK7/JNKK2

@nl

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Nature Cell Biology

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Gadd45 beta mediates the NF-kappa B suppression of JNK signalling by targeting MKK7/JNKK2

@en

P2093

Andreas H Nelsbach

http://www.w3.org/2001/XMLSchema#string

Can G Pham

http://www.w3.org/2001/XMLSchema#string

Dung U Nguyen

http://www.w3.org/2001/XMLSchema#string

Guido Franzoso

http://www.w3.org/2001/XMLSchema#string

Kellean Alvarez

http://www.w3.org/2001/XMLSchema#string

Shanthi Jayawardena

http://www.w3.org/2001/XMLSchema#string

Shuji Matsuda

http://www.w3.org/2001/XMLSchema#string

Tiziana Melis

http://www.w3.org/2001/XMLSchema#string

P2860

A human homolog of the yeast Ssk2/Ssk22 MAP kinase kinase kinases, MTK1, mediates stress-induced activation of the p38 and JNK pathways

Crystal structure of the p27Kip1 cyclin-dependent-kinase inhibitor bound to the cyclin A-Cdk2 complex

Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1.

MKK7 is an essential component of the JNK signal transduction pathway activated by proinflammatory cytokines

Gadd45 beta mediates the protective effects of CD40 costimulation against Fas-induced apoptosis

Mammalian MAP kinase signalling cascades

Identification of c-Jun NH2-terminal protein kinase (JNK)-activating kinase 2 as an activator of JNK but not p38

Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases

NF-kappaB at the crossroads of life and death

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146-53

http://www.w3.org/2001/XMLSchema#string

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scholarly article

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2299309

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10.1038/NCB1093

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2

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6

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Enrico De Smaele

Luciano D'Adamio

Luciano D'Adamio

Francesca Zazzeroni

Concetta Bubici

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2004-02-01T00:00:00Z

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8903620

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1049081004

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14743220

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