Type Igamma661 phosphatidylinositol phosphate kinase directly interacts with AP2 and regulates endocytosis
about
CKIalpha is associated with and phosphorylates star-PAP and is also required for expression of select star-PAP target messenger RNAsIQGAP1 is a novel phosphatidylinositol 4,5 bisphosphate effector in regulation of directional cell migration.Phosphoinositide signaling regulates the exocyst complex and polarized integrin trafficking in directionally migrating cellsStimulation of phosphatidylinositol kinase type I-mediated phosphatidylinositol (4,5)-bisphosphate synthesis by AP-2mu-cargo complexesType I gamma phosphatidylinositol phosphate kinase modulates adherens junction and E-cadherin trafficking via a direct interaction with mu 1B adaptinPhosphoinositides: tiny lipids with giant impact on cell regulationLipid kinases as therapeutic targets for chronic painMolecular Basis for Association of PIPKI -p90 with Clathrin Adaptor AP-2PtdIns(4,5)P2 turnover is required for multiple stages during clathrin- and actin-dependent endocytic internalizationPIP kinases define PI4,5P₂signaling specificity by association with effectorsEmerging roles of PtdIns(4,5)P2--beyond the plasma membraneRole of activation of PIP5Kgamma661 by AP-2 complex in synaptic vesicle endocytosisPhosphatidylinositol-4-phosphate 5-kinases and phosphatidylinositol 4,5-bisphosphate synthesis in the brainPhosphatidylinositol-4-kinase type II alpha contains an AP-3-sorting motif and a kinase domain that are both required for endosome trafficLMBD1 protein serves as a specific adaptor for insulin receptor internalizationLAPTM4B is a PtdIns(4,5)P2 effector that regulates EGFR signaling, lysosomal sorting, and degradation.Harnessing the power of the endosome to regulate neural development.Phosphatidylinositol 3,4,5-trisphosphate localization in recycling endosomes is necessary for AP-1B-dependent sorting in polarized epithelial cellsType Igamma PIP kinase is a novel uropod component that regulates rear retraction during neutrophil chemotaxis.The PCH family member proline-serine-threonine phosphatase-interacting protein 1 targets to the leukocyte uropod and regulates directed cell migration.PIPKI gamma 90 negatively regulates LFA-1-mediated adhesion and activation in antigen-induced CD4+ T cells.Phosphatidylinositol-(4,5)-bisphosphate regulates clathrin-coated pit initiation, stabilization, and sizeAcute depletion of plasma membrane phosphatidylinositol 4,5-bisphosphate impairs specific steps in endocytosis of the G-protein-coupled receptor.Isoform 5 of PIPKIγ regulates the endosomal trafficking and degradation of E-cadherin.Type I gamma phosphatidylinositol phosphate kinase modulates invasion and proliferation and its expression correlates with poor prognosis in breast cancer.The inositol 5-phosphatase SHIP2 regulates endocytic clathrin-coated pit dynamicsPIP5KIβ selectively modulates apical endocytosis in polarized renal epithelial cellsARF6 regulates neuron differentiation through glucosylceramide synthase.Development of a High-Throughput Screening Assay to Identify Inhibitors of the Lipid Kinase PIP5K1CAn association between type Iγ PI4P 5-kinase and Exo70 directs E-cadherin clustering and epithelial polarizationA novel gene expression pathway regulated by nuclear phosphoinositidesA C-terminal tyrosine-based motif in the bile salt export pump directs clathrin-dependent endocytosis.Resolution of structure of PIP5K1A reveals molecular mechanism for its regulation by dimerization and dishevelled.Type I gamma phosphatidylinositol phosphate kinase is required for EGF-stimulated directional cell migrationRole of phosphoinositides at the neuronal synapse.Phosphoinositide-metabolizing enzymes at the interface between membrane traffic and cell signallingA conspicuous connection: structure defines function for the phosphatidylinositol-phosphate kinase family.YRRL motifs in the cytoplasmic domain of the thrombopoietin receptor regulate receptor internalization and degradation.The AP-2 adaptor beta2 appendage scaffolds alternate cargo endocytosis.Endosomal type Iγ PIP 5-kinase controls EGF receptor lysosomal sorting
P2860
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P2860
Type Igamma661 phosphatidylinositol phosphate kinase directly interacts with AP2 and regulates endocytosis
description
2006 nî lūn-bûn
@nan
2006 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Type Igamma661 phosphatidylino ...... AP2 and regulates endocytosis
@ast
Type Igamma661 phosphatidylino ...... AP2 and regulates endocytosis
@en
Type Igamma661 phosphatidylino ...... AP2 and regulates endocytosis
@nl
type
label
Type Igamma661 phosphatidylino ...... AP2 and regulates endocytosis
@ast
Type Igamma661 phosphatidylino ...... AP2 and regulates endocytosis
@en
Type Igamma661 phosphatidylino ...... AP2 and regulates endocytosis
@nl
prefLabel
Type Igamma661 phosphatidylino ...... AP2 and regulates endocytosis
@ast
Type Igamma661 phosphatidylino ...... AP2 and regulates endocytosis
@en
Type Igamma661 phosphatidylino ...... AP2 and regulates endocytosis
@nl
P2093
P356
P1476
Type Igamma661 phosphatidylino ...... AP2 and regulates endocytosis
@en
P2093
Chateen Carbonara
Shawn F Bairstow
Xiaojing Su
P304
20632-20642
P356
10.1074/JBC.M601465200
P407
P577
2006-05-17T00:00:00Z