Angptl4 upregulates cholesterol synthesis in liver via inhibition of LPL- and HL-dependent hepatic cholesterol uptake
about
Angptl4 protects against severe proinflammatory effects of saturated fat by inhibiting fatty acid uptake into mesenteric lymph node macrophagesThe angiopoietin-like proteins ANGPTL3 and ANGPTL4 inhibit lipoprotein lipase activity through distinct mechanismsFatty acid-inducible ANGPTL4 governs lipid metabolic response to exerciseAngiopoietin-like 4: a decade of researchAngiopoietin-like protein 4: health effects, modulating agents and structure-function relationshipsAngiopoietin-like protein 4 inhibition of lipoprotein lipase: evidence for reversible complex formationANGPTL4 is produced by entero-endocrine cells in the human intestinal tractTargeted deletion of fibrinogen like protein 1 reveals a novel role in energy substrate utilizationThe ER-associated degradation adaptor protein Sel1L regulates LPL secretion and lipid metabolismComparative transcriptional network modeling of three PPAR-α/γ co-agonists reveals distinct metabolic gene signatures in primary human hepatocytesEffect of synthetic dietary triglycerides: a novel research paradigm for nutrigenomics.A novel model of cholesterol efflux from lipid-loaded cellsSex-different hepaticglycogen content and glucose output in rats.Decreased fat storage by Lactobacillus paracasei is associated with increased levels of angiopoietin-like 4 protein (ANGPTL4)Differential association of plasma angiopoietin-like proteins 3 and 4 with lipid and metabolic traits.Genetic causes of high and low serum HDL-cholesterol.Differential modulation by Akkermansia muciniphila and Faecalibacterium prausnitzii of host peripheral lipid metabolism and histone acetylation in mouse gut organoids.Inflammation increases plasma angiopoietin-like protein 4 in patients with the metabolic syndrome and type 2 diabetes.Lipoprotein lipase: from gene to obesity.The WWOX gene modulates high-density lipoprotein and lipid metabolism.microRNA-379 couples glucocorticoid hormones to dysfunctional lipid homeostasis.Lipase maturation factor 1: a lipase chaperone involved in lipid metabolism.Lactobacillus rhamnosus CNCMI-4317 Modulates Fiaf/Angptl4 in Intestinal Epithelial Cells and Circulating Level in Mice.Long-Term Feeding of Chitosan Ameliorates Glucose and Lipid Metabolism in a High-Fructose-Diet-Impaired Rat Model of Glucose Tolerance.Liver-specific loss of lipolysis-stimulated lipoprotein receptor triggers systemic hyperlipidemia in mice.All-trans-retinoic acid represses obesity and insulin resistance by activating both peroxisome proliferation-activated receptor beta/delta and retinoic acid receptor.Variation in ANGPTL4 and risk of coronary heart disease: the Atherosclerosis Risk in Communities StudyImproved cholesterol phenotype analysis by a model relating lipoprotein life cycle processes to particle size.Potential mediators linking gut bacteria to metabolic health: a critical view.Potential Role of ANGPTL4 in the Cross Talk between Metabolism and Cancer through PPAR Signaling Pathway.Role of Angptl4 in vascular permeability and inflammation.Angptl4 serves as an endogenous inhibitor of intestinal lipid digestion.Diet × genotype interactions in hepatic cholesterol and lipoprotein metabolism in Atlantic salmon (Salmo salar) in response to replacement of dietary fish oil with vegetable oil.Bacterial monocultures, propionate, butyrate and H2O2 modulate the expression, secretion and structure of the fasting-induced adipose factor in gut epithelial cell lines.Secretion of triacylglycerol-poor VLDL particles from McA-RH7777 cells expressing human hepatic lipase.Peroxisome proliferator-activated receptor beta/delta (PPARbeta/delta) but not PPARalpha serves as a plasma free fatty acid sensor in liver.Stabilizing lipoprotein lipaseTSC22D4 is a molecular output of hepatic wasting metabolism.A highly conserved motif within the NH2-terminal coiled-coil domain of angiopoietin-like protein 4 confers its inhibitory effects on lipoprotein lipase by disrupting the enzyme dimerization.Genetic variation in ANGPTL4 provides insights into protein processing and function.
P2860
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P2860
Angptl4 upregulates cholesterol synthesis in liver via inhibition of LPL- and HL-dependent hepatic cholesterol uptake
description
2007 nî lūn-bûn
@nan
2007 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Angptl4 upregulates cholestero ...... ent hepatic cholesterol uptake
@ast
Angptl4 upregulates cholestero ...... ent hepatic cholesterol uptake
@en
Angptl4 upregulates cholestero ...... ent hepatic cholesterol uptake
@nl
type
label
Angptl4 upregulates cholestero ...... ent hepatic cholesterol uptake
@ast
Angptl4 upregulates cholestero ...... ent hepatic cholesterol uptake
@en
Angptl4 upregulates cholestero ...... ent hepatic cholesterol uptake
@nl
prefLabel
Angptl4 upregulates cholestero ...... ent hepatic cholesterol uptake
@ast
Angptl4 upregulates cholestero ...... ent hepatic cholesterol uptake
@en
Angptl4 upregulates cholestero ...... ent hepatic cholesterol uptake
@nl
P2093
P50
P3181
P1476
Angptl4 upregulates cholestero ...... ent hepatic cholesterol uptake
@en
P2093
André Bensadoun
Ido P Kema
Jimmy F P Berbée
Ko Willems van Dijk
Peter J Voshol
Susan J van Dijk
P304
P3181
P356
10.1161/ATVBAHA.107.151894
P407
P577
2007-08-30T00:00:00Z