Hedgehog signaling and Bmi-1 regulate self-renewal of normal and malignant human mammary stem cells - Wikidata - wikimedia - TriplyDB

Hedgehog signaling and Bmi-1 regulate self-renewal of normal and malignant human mammary stem cells

Hedgehog signaling and Bmi-1 regulate self-renewal of normal and malignant human mammary stem cells

http://www.wikidata.org/entity/Q28246460

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Non-small cell lung cancer cells expressing CD44 are enriched for stem cell-like properties Recognition of UbcH5c and the nucleosome by the Bmi1/Ring1b ubiquitin ligase complex BMI-1 promotes ewing sarcoma tumorigenicity independent of CDKN2A repression The epithelial-mesenchymal transition generates cells with properties of stem cells Mel-18 acts as a tumor suppressor by repressing Bmi-1 expression and down-regulating Akt activity in breast cancer cells IL-6 triggers malignant features in mammospheres from human ductal breast carcinoma and normal mammary gland New molecularly targeted therapies for lung cancer Mel-18, a polycomb group protein, regulates cell proliferation and senescence via transcriptional repression of Bmi-1 and c-Myc oncoproteins The hedgehog pathway in triple-negative breast cancer TWIST1 and BMI1 in Cancer Metastasis and Chemoresistance Anti-Cancer Stem-like Cell Compounds in Clinical Development - An Overview and Critical Appraisal Therapeutic Effectiveness of Anticancer Phytochemicals on Cancer Stem Cells Yin Yang 1 is associated with cancer stem cell transcription factors (SOX2, OCT4, BMI1) and clinical implication Targeting the Sonic Hedgehog Signaling Pathway: Review of Smoothened and GLI Inhibitors Withaferin-A--A Natural Anticancer Agent with Pleitropic Mechanisms of Action New Findings on Breast Cancer Stem Cells: A Review Targeting self-renewal pathways in cancer stem cells: clinical implications for cancer therapy Common stemness regulators of embryonic and cancer stem cells The Role of Hedgehog Signaling in Tumor Induced Bone Disease Hedgehog Signaling in the Maintenance of Cancer Stem Cells Cancer stem cells--important players in tumor therapy resistance miRNAs in breast cancer tumorigenesis (Review)Emerging role of cancer stem cells in the biology and treatment of ovarian cancer: basic knowledge and therapeutic possibilities for an innovative approach Breast cancer epithelial-to-mesenchymal transition: examining the functional consequences of plasticity Identifying and targeting tumor-initiating cells in the treatment of breast cancer Cooperative integration between HEDGEHOG-GLI signalling and other oncogenic pathways: implications for cancer therapy Emerging therapeutic biomarkers in endometrial cancer Hedgehog signaling inhibitors as anti-cancer agents in osteosarcoma Mammary stem cells and the differentiation hierarchy: current status and perspectives Links between cancer stem cells and epithelial-mesenchymal transition The Role of microRNAs in Stemness of Cancer Stem Cells Wound healing and cancer stem cells: inflammation as a driver of treatment resistance in breast cancer A microRNA code for prostate cancer metastasis.The Anti-Cancer Effect of Polyphenols against Breast Cancer and Cancer Stem Cells: Molecular Mechanisms Mammary gland stem cells and their application in breast cancer Type 3 deiodinase: role in cancer growth, stemness, and metabolism Molecular pathways: novel approaches for improved therapeutic targeting of Hedgehog signaling in cancer stem cells Cancer stem cells in basic science and in translational oncology: can we translate into clinical application?FOXC1 Activates Smoothened-Independent Hedgehog Signaling in Basal-like Breast Cancer Phosphatase and tensin homolog deleted on chromosome 10 (PTEN) and PH domain and leucine-rich repeat phosphatase cross-talk (PHLPP) in cancer cells and in transforming growth factor β-activated stem cells

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Hedgehog signaling and Bmi-1 regulate self-renewal of normal and malignant human mammary stem cells

http://www.wikidata.org/entity/Q28246460

description

2006 nî lūn-bûn

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2006 թուականի Յունիսին հրատարակուած գիտական յօդուած

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2006年の論文

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2006年論文

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Hedgehog signaling and Bmi-1 r ...... gnant human mammary stem cells

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Hedgehog signaling and Bmi-1 r ...... gnant human mammary stem cells

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Hedgehog signaling and Bmi-1 r ...... gnant human mammary stem cells

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Hedgehog signaling and Bmi-1 r ...... gnant human mammary stem cells

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Hedgehog signaling and Bmi-1 r ...... gnant human mammary stem cells

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Hedgehog signaling and Bmi-1 r ...... gnant human mammary stem cells

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Hedgehog signaling and Bmi-1 r ...... gnant human mammary stem cells

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Hedgehog signaling and Bmi-1 r ...... gnant human mammary stem cells

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Hedgehog signaling and Bmi-1 r ...... gnant human mammary stem cells

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Gabriela Dontu

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Ilia D Mantle

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Kyle W Jackson

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Max S Wicha

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Nam-shik Ahn

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Prerna Suri

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Shivani Patel

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Suling Liu

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P2860

Role of Notch signaling in cell-fate determination of human mammary stem/progenitor cells

GLI2 is expressed in normal human epidermis and BCC and induces GLI1 expression by binding to its promoter

Human GLI2 and GLI1 are part of a positive feedback mechanism in Basal Cell Carcinoma

Microarray analysis identifies a death-from-cancer signature predicting therapy failure in patients with multiple types of cancer

Bmi-1 promotes neural stem cell self-renewal and neural development but not mouse growth and survival by repressing the p16Ink4a and p19Arf senescence pathways.

Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation

Inhibition of Hedgehog signaling by direct binding of cyclopamine to Smoothened

Prospective identification of tumorigenic breast cancer cells

Stem cells, cancer, and cancer stem cells

Identification of a cancer stem cell in human brain tumors

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