IL-6 triggers malignant features in mammospheres from human ductal breast carcinoma and normal mammary gland - Wikidata - wikimedia - TriplyDB

IL-6 triggers malignant features in mammospheres from human ductal breast carcinoma and normal mammary gland

IL-6 triggers malignant features in mammospheres from human ductal breast carcinoma and normal mammary gland

http://www.wikidata.org/entity/Q24669531

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The notch ligand JAGGED1 as a target for anti-tumor therapy Acid beta-glucosidase 1 counteracts p38delta-dependent induction of interleukin-6: possible role for ceramide as an anti-inflammatory lipid HER2 overexpression elicits a proinflammatory IL-6 autocrine signaling loop that is critical for tumorigenesis Epigenetic control of the basal-like gene expression profile via Interleukin-6 in breast cancer cells CXCR1 blockade selectively targets human breast cancer stem cells in vitro and in xenografts NOTCH3 expression is induced in mural cells through an autoregulatory loop that requires endothelial-expressed JAGGED1 Potential therapeutic implications of IL-6/IL-6R/gp130-targeting agents in breast cancer The Role of the Transcriptional Regulation of Stromal Cells in Chronic Inflammation Implications of the Hybrid Epithelial/Mesenchymal Phenotype in Metastasis Epithelial-mesenchymal plasticity of breast cancer stem cells: implications for metastasis and therapeutic resistance Targeting the tumor microenvironment: JAK-STAT3 signaling Targeting the Notch signaling pathway in cancer therapeutics Mesenchymal stem cell secretome and regenerative therapy after cancer Preclinical validation of interleukin 6 as a therapeutic target in multiple myeloma PD-L1 (B7-H1) and PD-1 pathway blockade for cancer therapy: Mechanisms, response biomarkers, and combinations The cancer stem cell niche--there goes the neighborhood?Dangerous liaisons: STAT3 and NF-kappaB collaboration and crosstalk in cancer Sustained proliferation in cancer: Mechanisms and novel therapeutic targets SNAI1-mediated epithelial-mesenchymal transition confers chemoresistance and cellular plasticity by regulating genes involved in cell death and stem cell maintenance IL-6 and Stat3 are required for survival of intestinal epithelial cells and development of colitis-associated cancer Breast cancer cell lines contain functional cancer stem cells with metastatic capacity and a distinct molecular signature Nitric oxide is a key component in inflammation-accelerated tumorigenesis.Orai1 promotes tumor progression by enhancing cancer stemness via NFAT signaling in oral/oropharyngeal squamous cell carcinoma.Tumor-like stem cells derived from human keloid are governed by the inflammatory niche driven by IL-17/IL-6 axis.HMGA1a recognition candidate DNA sequences in humans.Systematic analysis of secreted proteins reveals synergism between IL6 and other proteins in soft agar growth of MCF10A cells Differential baseline and response profile to IFN-gamma gene transduction of IL-6/IL-6 receptor-alpha secretion discriminate primary tumors versus bone marrow metastases of nasopharyngeal carcinomas in culture.Down-regulation of the fetal stem cell factor SOX17 by H33342: a mechanism responsible for differential gene expression in breast cancer side population cells.Identification of liver cancer progenitors whose malignant progression depends on autocrine IL-6 signaling Interleukin 6 secreted from adipose stromal cells promotes migration and invasion of breast cancer cells.Endothelial cell-derived interleukin-6 regulates tumor growth.Bacteria peptidoglycan promoted breast cancer cell invasiveness and adhesiveness by targeting toll-like receptor 2 in the cancer cells Benign mammary epithelial cells enhance the transformed phenotype of human breast cancer cells.SLUG/SNAI2 and tumor necrosis factor generate breast cells with CD44+/CD24- phenotype.Prognostic impact of C-reactive protein/albumin ratio on the overall survival of patients with advanced nonsmall cell lung cancers receiving palliative chemotherapy Targeting interleukin 6 signaling suppresses glioma stem cell survival and tumor growth HER2 in Breast Cancer Stemness: A Negative Feedback Loop towards Trastuzumab Resistance.Changes in aldehyde dehydrogenase-1 expression during neoadjuvant chemotherapy predict outcome in locally advanced breast cancer Top Notch cancer stem cells by paracrine NF-κB signaling in breast cancer.Defects in innate immunity render breast cancer initiating cells permissive to oncolytic adenovirus.

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IL-6 triggers malignant features in mammospheres from human ductal breast carcinoma and normal mammary gland

http://www.wikidata.org/entity/Q24669531

description

2007 nî lūn-bûn

@nan

2007 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2007 թվականի դեկտեմբերին հրատարակված գիտական հոդված

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2007年の論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年论文

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name

IL-6 triggers malignant featur ...... inoma and normal mammary gland

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IL-6 triggers malignant featur ...... inoma and normal mammary gland

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IL-6 triggers malignant featur ...... inoma and normal mammary gland

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type

label

IL-6 triggers malignant featur ...... inoma and normal mammary gland

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IL-6 triggers malignant featur ...... inoma and normal mammary gland

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IL-6 triggers malignant featur ...... inoma and normal mammary gland

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prefLabel

IL-6 triggers malignant featur ...... inoma and normal mammary gland

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IL-6 triggers malignant featur ...... inoma and normal mammary gland

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IL-6 triggers malignant featur ...... inoma and normal mammary gland

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Journal of Clinical Investigation

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P2093

Donatella Santini

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Kenneth B Marcu

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Mario Taffurelli

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Massimiliano Bonafè

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Paola Paterini

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Pasquale Sansone

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Tiziana Guarnieri

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P2860

Exquisite sensitivity of TP53 mutant and basal breast cancers to a dose-dense epirubicin-cyclophosphamide regimen

Role of Notch signaling in cell-fate determination of human mammary stem/progenitor cells

Inflammation and cancer

Prospective identification of tumorigenic breast cancer cells

Metalloproteinases: role in breast carcinogenesis, invasion and metastasis

A human colon cancer cell capable of initiating tumour growth in immunodeficient mice

Stem cells, cancer, and cancer stem cells

Identification of human brain tumour initiating cells

Hedgehog signaling and Bmi-1 regulate self-renewal of normal and malignant human mammary stem cells

High-level coexpression of JAG1 and NOTCH1 is observed in human breast cancer and is associated with poor overall survival

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3988-4002

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1949646

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10.1172/JCI32533

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12

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117

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Pasquale Chieco

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Catia Giovannini

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18060036

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