IRAK-2 participates in multiple toll-like receptor signaling pathways to NFkappaB via activation of TRAF6 ubiquitination
about
Subversion of innate defenses by the interplay between DENV and pre-existing enhancing antibodies: TLRs signaling collapseViral immune modulators perturb the human molecular network by common and unique strategiesViral targeting of DEAD box protein 3 reveals its role in TBK1/IKKepsilon-mediated IRF activationEndotoxin tolerance impairs IL-1 receptor-associated kinase (IRAK) 4 and TGF-beta-activated kinase 1 activation, K63-linked polyubiquitination and assembly of IRAK1, TNF receptor-associated factor 6, and IkappaB kinase gamma and increases A20 expresPathogen recognition and inflammatory signaling in innate immune defensesToll-like receptors: key players in antiviral immunityDeconstructing innate immune signaling in myelodysplastic syndromesA mutation in Irak2c identifies IRAK-2 as a central component of the TLR regulatory network of wild-derived miceVaccinia Virus Proteins A52 and B14 Share a Bcl-2–Like Fold but Have Evolved to Inhibit NF-κB rather than ApoptosisCharacterization and Structure of the Vaccinia Virus NF-κB Antagonist A46Interleukin-1 receptor-associated kinase 2- and protein kinase D1-dependent regulation of IRAK-monocyte expression by CpG DNADifferential proteomic analysis of respiratory samples from patients suffering from influenzaInterleukin-1 receptor-associated kinase-2 genetic variant rs708035 increases NF-κB activity through promoting TRAF6 ubiquitinationGene expression profiling of dendritic cells reveals important mechanisms associated with predisposition to Staphylococcus infectionsA coding IRAK2 protein variant compromises Toll-like receptor (TLR) signaling and is associated with colorectal cancer survival.Differential expression of interleukin-1/Toll-like receptor signaling regulators in microscopic and ulcerative colitis.Differential regulation of interleukin-1 receptor-associated kinase-1 (IRAK-1) and IRAK-2 by microRNA-146a and NF-kappaB in stressed human astroglial cells and in Alzheimer disease.Toll-like receptor 2 agonists inhibit human fibrocyte differentiation.Interleukin-1 receptor-associated kinase-2 (IRAK2) is a critical mediator of endoplasmic reticulum (ER) stress signalingDouble-stranded RNA induces shedding of the 34-kDa soluble TNFR1 from human airway epithelial cells via TLR3-TRIF-RIP1-dependent signaling: roles for dual oxidase 2- and caspase-dependent pathways.Importance of innate mucosal immunity and the promises it holds.Human interleukin-1 receptor-associated kinase-2 is essential for Toll-like receptor-mediated transcriptional and post-transcriptional regulation of tumor necrosis factor alphaA functional polymorphism in the promoter region of microRNA-146a is associated with the risk of Alzheimer disease and the rate of cognitive decline in patients.Type I interferon signaling contributes to the bias that Toll-like receptor 4 exhibits for signaling mediated by the adaptor protein TRIF.Chronic inflammation in cancer development.TRAF6 protein couples Toll-like receptor 4 signaling to Src family kinase activation and opening of paracellular pathway in human lung microvascular endothelia.Upregulation of TLR1, TLR2, TLR4, and IRAK-2 Expression During ML-1 Cell Differentiation to Macrophages: Role in the Potentiation of Cellular Responses to LPS and LTA.Poxviral protein A46 antagonizes Toll-like receptor 4 signaling by targeting BB loop motifs in Toll-IL-1 receptor adaptor proteins to disrupt receptor:adaptor interactionsBrazilein Suppresses Inflammation through Inactivation of IRAK4-NF-κB Pathway in LPS-Induced Raw264.7 Macrophage CellsTumor necrosis factor receptor-associated factor 6 (TRAF6) and TGFβ-activated kinase 1 (TAK1) play essential roles in the C-type lectin receptor signaling in response to Candida albicans infection.Links between Toll-like receptor 4 and breast cancerThe involvement of the interleukin-1 receptor-associated kinases (IRAKs) in cellular signaling networks controlling inflammationToll-like receptor polymorphisms, inflammatory and infectious diseases, allergies, and cancer.Interleukin-1 receptor-associated kinase 2 is critical for lipopolysaccharide-mediated post-transcriptional control.Protein kinase D1 is essential for MyD88-dependent TLR signaling pathwayActivated protein C protects against ventilator-induced pulmonary capillary leakRole of non-degradative ubiquitination in interleukin-1 and toll-like receptor signaling.Multiple Bcl-2 family immunomodulators from vaccinia virus regulate MAPK/AP-1 activationPoxviral protein A52 stimulates p38 mitogen-activated protein kinase (MAPK) activation by causing tumor necrosis factor receptor-associated factor 6 (TRAF6) self-association leading to transforming growth factor β-activated kinase 1 (TAK1) recruitmeTwo phases of inflammatory mediator production defined by the study of IRAK2 and IRAK1 knock-in mice.
P2860
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P2860
IRAK-2 participates in multiple toll-like receptor signaling pathways to NFkappaB via activation of TRAF6 ubiquitination
description
2007 nî lūn-bûn
@nan
2007 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
IRAK-2 participates in multipl ...... vation of TRAF6 ubiquitination
@ast
IRAK-2 participates in multipl ...... vation of TRAF6 ubiquitination
@en
IRAK-2 participates in multipl ...... vation of TRAF6 ubiquitination
@nl
type
label
IRAK-2 participates in multipl ...... vation of TRAF6 ubiquitination
@ast
IRAK-2 participates in multipl ...... vation of TRAF6 ubiquitination
@en
IRAK-2 participates in multipl ...... vation of TRAF6 ubiquitination
@nl
prefLabel
IRAK-2 participates in multipl ...... vation of TRAF6 ubiquitination
@ast
IRAK-2 participates in multipl ...... vation of TRAF6 ubiquitination
@en
IRAK-2 participates in multipl ...... vation of TRAF6 ubiquitination
@nl
P2093
P2860
P356
P1476
IRAK-2 participates in multipl ...... vation of TRAF6 ubiquitination
@en
P2093
Andrew G Bowie
Ellen M Moran
Geraldine M Maloney
Sinead E Keating
P2860
P304
P356
10.1074/JBC.M705266200
P407
P577
2007-11-16T00:00:00Z