about
Inhibition of the EGF receptor by binding of MIG6 to an activating kinase domain interfaceChk1 phosphorylates the tumour suppressor Mig-6, regulating the activation of EGF signallingThe evolutionarily conserved EBR module of RALT/MIG6 mediates suppression of the EGFR catalytic activityGADD45gamma: a new vitamin D-regulated gene that is antiproliferative in prostate cancer cellsThe role of small adaptor proteins in the control of oncogenic signalingr driven by tyrosine kinases in human cancerIntegrated genomic characterization reveals novel, therapeutically relevant drug targets in FGFR and EGFR pathways in sporadic intrahepatic cholangiocarcinomaGene 33/Mig6 inhibits hexavalent chromium-induced DNA damage and cell transformation in human lung epithelial cellsMitogen-Inducible Gene-6 Mediates Feedback Inhibition from Mutated BRAF towards the Epidermal Growth Factor Receptor and Thereby Limits Malignant TransformationGlucocorticoid-induced suppression of β-cell proliferation is mediated by Mig6Mig-6 is required for appropriate lung development and to ensure normal adult lung homeostasisThe synergistic effect of Mig-6 and Pten ablation on endometrial cancer development and progression.ERBB receptor feedback inhibitor 1 regulation of estrogen receptor activity is critical for uterine implantation in mice.Epidermal growth factor receptor mutation in combination with expression of MIG6 alters gefitinib sensitivity.Mig-6 controls EGFR trafficking and suppresses gliomagenesisIntegrated genomic analyses identify ERRFI1 and TACC3 as glioblastoma-targeted genes.Cancer-type regulation of MIG-6 expression by inhibitors of methylation and histone deacetylation.Decreased Mitogen Inducible Gene 6 (MIG-6) Associated with Symptom Severity in Children with Autism.Mig-6 plays a critical role in the regulation of cholesterol homeostasis and bile acid synthesis.The epidermal growth factor receptor family: biology driving targeted therapeutics.Mig-6 suppresses endometrial cancer associated with Pten deficiency and ERK activation.Mig-6 gene knockout induces neointimal hyperplasia in the vascular smooth muscle cell.The antitumorigenic function of EGFR in metastatic breast cancer is regulated by expression of Mig6.Whole genome sequencing of glioblastoma multiforme identifies multiple structural variations involved in EGFR activationUnderstanding the molecular basis of EGFR kinase domain/MIG-6 peptide recognition complex using computational analysesMig-6 regulates endometrial genes involved in cell cycle and progesterone signaling.Loss of MIG6 Accelerates Initiation and Progression of Mutant Epidermal Growth Factor Receptor-Driven Lung Adenocarcinoma.Overexpression and knockout of miR-126 both promote leukemogenesisThyroid-specific knockout of the tumor suppressor mitogen-inducible gene 6 activates epidermal growth factor receptor signaling pathways and suppresses nuclear factor-κB activityMitogen-inducible gene 6 triggers apoptosis and exacerbates ER stress-induced β-cell death.Structure and mechanism of activity-based inhibition of the EGF receptor by Mig6Perifosine induces differentiation and cell death in prostate cancer cellsMig6 is a sensor of EGF receptor inactivation that directly activates c-Abl to induce apoptosis during epithelial homeostasisComparisons of tyrosine phosphorylated proteins in cells expressing lung cancer-specific alleles of EGFR and KRASMig-6 modulates uterine steroid hormone responsiveness and exhibits altered expression in endometrial diseaseMechanisms of ErbB receptor negative regulation and relevance in cancer.The ErbB kinase domain: structural perspectives into kinase activation and inhibition.Functional genomics and proteomics approaches to study the ERBB network in cancer.Fatty Liver and Insulin Resistance in the Liver-Specific Knockout Mice of Mitogen Inducible Gene-6.Inhibition of Cdc42 is essential for Mig-6 suppression of cell migration induced by EGF.Cartilage-specific deletion of Mig-6 results in osteoarthritis-like disorder with excessive articular chondrocyte proliferation.
P2860
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P2860
description
2007 nî lūn-bûn
@nan
2007 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Evidence that MIG-6 is a tumor-suppressor gene
@ast
Evidence that MIG-6 is a tumor-suppressor gene
@en
Evidence that MIG-6 is a tumor-suppressor gene
@nl
type
label
Evidence that MIG-6 is a tumor-suppressor gene
@ast
Evidence that MIG-6 is a tumor-suppressor gene
@en
Evidence that MIG-6 is a tumor-suppressor gene
@nl
prefLabel
Evidence that MIG-6 is a tumor-suppressor gene
@ast
Evidence that MIG-6 is a tumor-suppressor gene
@en
Evidence that MIG-6 is a tumor-suppressor gene
@nl
P2093
P3181
P356
P1433
P1476
Evidence that MIG-6 is a tumor-suppressor gene
@en
P2093
G F Vande Woude
P2888
P304
P3181
P356
10.1038/SJ.ONC.1209790
P407
P577
2007-01-11T00:00:00Z
P5875
P6179
1049392933