Genomic organization, alternative splicing, and expression patterns of the DSCR1 (Down syndrome candidate region 1) gene
about
VEGF stimulates RCAN1.4 expression in endothelial cells via a pathway requiring Ca2+/calcineurin and protein kinase C-deltaMutational analyses of the signals involved in the subcellular location of DSCR1.Phosphorylation of calcipressin 1 increases its ability to inhibit calcineurin and decreases calcipressin half-lifeNovel human ZAKI-4 isoforms: hormonal and tissue-specific regulation and function as calcineurin inhibitorsDown's syndrome suppression of tumour growth and the role of the calcineurin inhibitor DSCR1Down syndrome candidate region 1,a downstream target of VEGF, participates in endothelial cell migration and angiogenesisThe vertebrate RCAN gene family: novel insights into evolution, structure and regulationRCAN1 Overexpression Exacerbates Calcium Overloading-Induced Neuronal ApoptosisA statistical method for predicting splice variants between two groups of samples using GeneChip expression array dataCo-expression network analysis of Down's syndrome based on microarray data.A calcineurin inhibitory protein overexpressed in Down's syndrome interacts with the product of a ubiquitously expressed transcript.NF-kappaB-inducing kinase phosphorylates and blocks the degradation of Down syndrome candidate region 1.Identification of a peptide fragment of DSCR1 that competitively inhibits calcineurin activity in vitro and in vivo.Complexity of bidirectional transcription and alternative splicing at human RCAN3 locus.Over-expression of RCAN1 causes Down syndrome-like hippocampal deficits that alter learning and memory.Chaperone-mediated autophagy regulates T cell responses through targeted degradation of negative regulators of T cell activation.Covalent NEDD8 conjugation increases RCAN1 protein stability and potentiates its inhibitory action on calcineurin.Dual roles of modulatory calcineurin-interacting protein 1 in cardiac hypertrophy.Pituitary Adenylate Cyclase-activating Polypeptide (PACAP) Targets Down Syndrome Candidate Region 1 (DSCR1/RCAN1) to control Neuronal Differentiation.RCAN1 is an important mediator of glucocorticoid-induced apoptosis in human leukemic cells.Overexpression of Rcan1-1L inhibits hypoxia-induced cell apoptosis through induction of mitophagyRegulator of calcineurin 1 (RCAN1) facilitates neuronal apoptosis through caspase-3 activation.Myocyte-enriched calcineurin-interacting protein, MCIP1, inhibits cardiac hypertrophy in vivoRegulator of calcineurin 1 (Rcan1) is required for the development of pulmonary eosinophilia in allergic inflammation in miceRegulator of Calcineurin 1 Isoform 4 (RCAN1.4) Is Overexpressed in the Glomeruli of Diabetic MiceTrisomy 21 and early brain developmentSystematic Tracking of Disrupted Modules Identifies Altered Pathways Associated with Congenital Heart Defects in Down Syndrome.Over-expression of DSCR1 protects against post-ischemic neuronal injuryRCAN1 links impaired neurotrophin trafficking to aberrant development of the sympathetic nervous system in Down syndrome.Creation and characterization of BAC-transgenic mice with physiological overexpression of epitope-tagged RCAN1 (DSCR1)Calcineurin regulation in fungi and beyondThe Down syndrome critical region gene 1 short variant promoters direct vascular bed-specific gene expression during inflammation in miceAllele-Specific Phenotype Suggests a Possible Stimulatory Activity of RCAN-1 on Calcineurin in Caenorhabditis elegans.RCANs regulate the convergent roles of NFATc1 in bone homeostasis.Systematic reanalysis of partial trisomy 21 cases with or without Down syndrome suggests a small region on 21q22.13 as critical to the phenotype.Interaction of calcineurin with substrates and targeting proteins.Calcineurin-NFAT activation and DSCR-1 auto-inhibitory loop: how is homoeostasis regulated?Aberrant expression of RCAN1 in Alzheimer's pathogenesis: a new molecular mechanism and a novel drug target.Thrombin-induced autoinhibitory factor, Down syndrome critical region-1, attenuates NFAT-dependent vascular cell adhesion molecule-1 expression and inflammation in the endothelium.Functional genomic analysis reveals cross-talk between peroxisome proliferator-activated receptor gamma and calcium signaling in human colorectal cancer cells.
P2860
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P2860
Genomic organization, alternative splicing, and expression patterns of the DSCR1 (Down syndrome candidate region 1) gene
description
1997 nî lūn-bûn
@nan
1997 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
Genomic organization, alternat ...... drome candidate region 1) gene
@ast
Genomic organization, alternat ...... drome candidate region 1) gene
@en
Genomic organization, alternat ...... drome candidate region 1) gene
@nl
type
label
Genomic organization, alternat ...... drome candidate region 1) gene
@ast
Genomic organization, alternat ...... drome candidate region 1) gene
@en
Genomic organization, alternat ...... drome candidate region 1) gene
@nl
prefLabel
Genomic organization, alternat ...... drome candidate region 1) gene
@ast
Genomic organization, alternat ...... drome candidate region 1) gene
@en
Genomic organization, alternat ...... drome candidate region 1) gene
@nl
P3181
P356
P1433
P1476
Genomic organization, alternat ...... drome candidate region 1) gene
@en
P2093
J J Fuentes
M A Pritchard
P304
P3181
P356
10.1006/GENO.1997.4866
P407
P577
1997-09-15T00:00:00Z