The adaptor protein shb binds to tyrosine 1175 in vascular endothelial growth factor (VEGF) receptor-2 and regulates VEGF-dependent cellular migration - Wikidata - wikimedia - TriplyDB

The adaptor protein shb binds to tyrosine 1175 in vascular endothelial growth factor (VEGF) receptor-2 and regulates VEGF-dependent cellular migration

The adaptor protein shb binds to tyrosine 1175 in vascular endothelial growth factor (VEGF) receptor-2 and regulates VEGF-dependent cellular migration

http://www.wikidata.org/entity/Q28250994

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MULTIMERIN2 impairs tumor angiogenesis and growth by interfering with VEGF-A/VEGFR2 pathway VEGF receptor-2 Y951 signaling and a role for the adapter molecule TSAd in tumor angiogenesis.Advances of Targeted Therapy in Treatment of Unresectable Metastatic Colorectal Cancer The Emerging Regulation of VEGFR-2 in Triple-Negative Breast Cancer Absence of the adaptor protein Shb potentiates the T helper type 2 response in a mouse model of atopic dermatitis Essential role of Flk-1 (VEGF receptor 2) tyrosine residue 1173 in vasculogenesis in mice Caveolin-1 plays a crucial role in inhibiting neuronal differentiation of neural stem/progenitor cells via VEGF signaling-dependent pathway The Src homology 2 domain-containing adapter protein B (SHB) regulates mouse oocyte maturation The SHB adapter protein is required for normal maturation of mesoderm during in vitro differentiation of embryonic stem cells Integrin β3 crosstalk with VEGFR accommodating tyrosine phosphorylation as a regulatory switch Phosphorylation of Akt and ERK1/2 is required for VEGF-A/VEGFR2-induced proliferation and migration of lymphatic endothelium VEGFA-VEGFR2 Signaling Pathway VEGFR2 induces c-Src signaling and vascular permeability in vivo via the adaptor protein TSAd.Orientation of endothelial cell division is regulated by VEGF signaling during blood vessel formation IQGAP1-dependent signaling pathway regulates endothelial cell proliferation and angiogenesis.Vascular adaptation to a dysfunctional endothelium as a consequence of Shb deficiency.Shb deficient mice display an augmented TH2 response in peripheral CD4+ T cells.Heterogeneity among RIP-Tag2 insulinomas allows vascular endothelial growth factor-A independent tumor expansion as revealed by studies in Shb mutant mice: implications for tumor angiogenesis TIMP-2 modulates VEGFR-2 phosphorylation and enhances phosphodiesterase activity in endothelial cells.VEGF-A isoforms differentially regulate ATF-2-dependent VCAM-1 gene expression and endothelial-leukocyte interactions.VEGFR-1 and VEGFR-2: two non-identical twins with a unique physiognomy CXCL17 expression by tumor cells recruits CD11b+Gr1 high F4/80- cells and promotes tumor progression.Leucine motif-dependent tyrosine autophosphorylation of type III receptor tyrosine kinases.Emerging roles of post-translational modifications in signal transduction and angiogenesis Priming of the vascular endothelial growth factor signaling pathway by thrombospondin-1, CD36, and spleen tyrosine kinase.Vascular endothelial growth factor receptors: molecular mechanisms of activation and therapeutic potentials.Total saponins from Albizia julibrissin inhibit vascular endothelial growth factor-mediated angiogenesis in vitro and in vivo Vascular dysfunction and increased metastasis of B16F10 melanomas in Shb deficient mice as compared with their wild type counterparts.A critical role for the E3-ligase activity of c-Cbl in VEGFR-2-mediated PLCgamma1 activation and angiogenesis.Endogenous vascular endothelial growth factor-A (VEGF-A) maintains endothelial cell homeostasis by regulating VEGF receptor-2 transcription.Effective treatment of diverse medulloblastoma models with mebendazole and its impact on tumor angiogenesis.Arnebin-1 promotes angiogenesis by inducing eNOS, VEGF and HIF-1α expression through the PI3K-dependent pathway.SmShb, the SH2-Containing Adaptor Protein B of Schistosoma mansoni Regulates Venus Kinase Receptor Signaling Pathways.Duplicate VegfA genes and orthologues of the KDR receptor tyrosine kinase family mediate vascular development in the zebrafish.RNA-seq reveals aurora kinase-driven mTOR pathway activation in patients with sarcomatoid metastatic renal cell carcinoma.Roles for VEGF in the adult.A novel synthetic small molecule YF-452 inhibits tumor growth through antiangiogenesis by suppressing VEGF receptor 2 signaling.The role of VEGF receptors in angiogenesis; complex partnerships Endorepellin affects angiogenesis by antagonizing diverse vascular endothelial growth factor receptor 2 (VEGFR2)-evoked signaling pathways: transcriptional repression of hypoxia-inducible factor 1α and VEGFA and concurrent inhibition of nuclear fact Both Kdr and Flt1 play a vital role in hypoxia-induced Src-PLD1-PKCγ-cPLA(2) activation and retinal neovascularization

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The adaptor protein shb binds to tyrosine 1175 in vascular endothelial growth factor (VEGF) receptor-2 and regulates VEGF-dependent cellular migration

http://www.wikidata.org/entity/Q28250994

description

2004 nî lūn-bûn

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2004 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2004 թվականի մայիսին հրատարակված գիտական հոդված

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2004年の論文

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2004年論文

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2004年論文

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2004年論文

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2004年論文

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2004年論文

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2004年论文

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name

The adaptor protein shb binds ...... F-dependent cellular migration

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The adaptor protein shb binds ...... F-dependent cellular migration

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The adaptor protein shb binds ...... F-dependent cellular migration

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type

label

The adaptor protein shb binds ...... F-dependent cellular migration

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The adaptor protein shb binds ...... F-dependent cellular migration

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The adaptor protein shb binds ...... F-dependent cellular migration

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prefLabel

The adaptor protein shb binds ...... F-dependent cellular migration

@ast

The adaptor protein shb binds ...... F-dependent cellular migration

@en

The adaptor protein shb binds ...... F-dependent cellular migration

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Journal of Biological Chemistry

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The adaptor protein shb binds ...... F-dependent cellular migration

@en

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Charlotte Rolny

http://www.w3.org/2001/XMLSchema#string

Kristina Holmqvist

http://www.w3.org/2001/XMLSchema#string

Lena Claesson-Welsh

http://www.w3.org/2001/XMLSchema#string

Michael J Cross

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Michael Welsh

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Nader Rahimi

http://www.w3.org/2001/XMLSchema#string

Robert Hägerkvist

http://www.w3.org/2001/XMLSchema#string

Taro Matsumoto

http://www.w3.org/2001/XMLSchema#string

P2860

A single autophosphorylation site on KDR/Flk-1 is essential for VEGF-A-dependent activation of PLC-gamma and DNA synthesis in vascular endothelial cells

Src kinase becomes preferentially associated with the VEGFR, KDR/Flk-1, following VEGF stimulation of vascular endothelial cells.

Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans

Interactions of FLT-1 and KDR with phospholipase C gamma: identification of the phosphotyrosine binding sites

Targeted deficiency or cytosolic truncation of the VE-cadherin gene in mice impairs VEGF-mediated endothelial survival and angiogenesis

Requirement of the Src homology 2 domain protein Shb for T cell receptor-dependent activation of the interleukin-2 gene nuclear factor for activation of T cells element in Jurkat T cells

Platelet-derived growth factor-mediated signaling through the Shb adaptor protein: effects on cytoskeletal organization

The Shb adaptor protein causes Src-dependent cell spreading and activation of focal adhesion kinase in murine brain endothelial cells

IL-2 receptor signaling through the Shb adapter protein in T and NK cells

Vascular endothelial growth factor stimulates tyrosine phosphorylation and recruitment to new focal adhesions of focal adhesion kinase and paxillin in endothelial cells

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22267-75

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2468335

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10.1074/JBC.M312729200

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21

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279

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2004-05-21T00:00:00Z

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15026417

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