A critical role for the E3-ligase activity of c-Cbl in VEGFR-2-mediated PLCgamma1 activation and angiogenesis.
about
Protein tyrosine kinase regulation by ubiquitination: critical roles of Cbl-family ubiquitin ligasesKIF13B regulates angiogenesis through Golgi to plasma membrane trafficking of VEGFR2IQGAP1-dependent signaling pathway regulates endothelial cell proliferation and angiogenesis.Role of c-Cbl-dependent regulation of phospholipase Cgamma1 activation in experimental choroidal neovascularizationc-Cbl inhibition improves cardiac function and survival in response to myocardial ischemiaLysine methylation promotes VEGFR-2 activation and angiogenesis.HIF-1α-independent hypoxia-induced rapid PTK6 stabilization is associated with increased motility and invasion.Negative regulation of EGFR-Vav2 signaling axis by Cbl ubiquitin ligase controls EGF receptor-mediated epithelial cell adherens junction dynamics and cell migration.A heat-shock protein axis regulates VEGFR2 proteolysis, blood vessel development and repair.Emerging roles of post-translational modifications in signal transduction and angiogenesisPEST motif serine and tyrosine phosphorylation controls vascular endothelial growth factor receptor 2 stability and downregulation.Role of c-Cbl carboxyl terminus in serotonin 5-HT2A receptor recycling and resensitization.The c-Cbl ubiquitin ligase regulates nuclear β-catenin and angiogenesis by its tyrosine phosphorylation mediated through the Wnt signaling pathway.The ubiquitin-proteasome system meets angiogenesis.AIP1 Expression in Tumor Niche Suppresses Tumor Progression and Metastasis.TMIGD1 is a novel adhesion molecule that protects epithelial cells from oxidative cell injuryc-Cbl, a ubiquitin E3 ligase that targets active β-catenin: a novel layer of Wnt signaling regulation.c-Cbl inhibits angiogenesis and tumor growth by suppressing activation of PLCγ1c-Cbl mediates the degradation of tumorigenic nuclear β-catenin contributing to the heterogeneity in Wnt activity in colorectal tumors.Regulation of VEGF signaling by membrane traffic.Role of E3 ubiquitin ligases in lung cancer.Ubiquitination of basal VEGFR2 regulates signal transduction and endothelial function.SUMOylation of VEGFR2 regulates its intracellular trafficking and pathological angiogenesisDerailing the UPS of Protein Turnover in Cancer and other Human Diseases
P2860
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P2860
A critical role for the E3-ligase activity of c-Cbl in VEGFR-2-mediated PLCgamma1 activation and angiogenesis.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
A critical role for the E3-lig ...... 1 activation and angiogenesis.
@ast
A critical role for the E3-lig ...... 1 activation and angiogenesis.
@en
type
label
A critical role for the E3-lig ...... 1 activation and angiogenesis.
@ast
A critical role for the E3-lig ...... 1 activation and angiogenesis.
@en
prefLabel
A critical role for the E3-lig ...... 1 activation and angiogenesis.
@ast
A critical role for the E3-lig ...... 1 activation and angiogenesis.
@en
P2093
P2860
P356
P1476
A critical role for the E3-lig ...... 1 activation and angiogenesis.
@en
P2093
Amrik J Singh
Gyulmagomed Navruzbekov
Hamid Band
Rajani Shelke
Rosana D Meyer
P2860
P304
P356
10.1073/PNAS.0700809104
P407
P50
P577
2007-03-19T00:00:00Z