HLA-DMA and -DMB genes are both required for MHC class II/peptide complex formation in antigen-presenting cells
about
HLA-DO is a lysosomal resident which requires association with HLA-DM for efficient intracellular transportImmunogenetics of Hashimoto's thyroiditisThe role of major histocompatibility complex molecules in luteal functionAchieving stability through editing and chaperoning: regulation of MHC class II peptide binding and expressionEditing of the HLA-DR-peptide repertoire by HLA-DMDecreased endosomal delivery of major histocompatibility complex class II-invariant chain complexes in dynamin-deficient cellsThe impact of the non-classical MHC proteins HLA-DM and HLA-DO on loading of MHC class II moleculesComprehensive analysis of MHC class II genes in teleost fish genomes reveals dispensability of the peptide-loading DM system in a large part of vertebrates.Analysis of 10,000 ESTs from lymphocytes of the cynomolgus monkey to improve our understanding of its immune system.Truncation of the class II beta-chain cytoplasmic domain influences the level of class II/invariant chain-derived peptide complexes.HLA-DRα1 constructs block CD74 expression and MIF effects in experimental autoimmune encephalomyelitis.Mechanisms of antigen presentation.Intracellular transport and peptide loading of MHC class II molecules: regulation by chaperones and motors.Peptide exchange in MHC molecules.Individual hydrogen bonds play a critical role in MHC class II: peptide interactions: implications for the dynamic aspects of class II trafficking and DM-mediated peptide exchange.The role of H2-O and HLA-DO in major histocompatibility complex class II-restricted antigen processing and presentation.Proteolysis of major histocompatibility complex class II-associated invariant chain is regulated by the alternatively spliced gene product, p41.The kinetic basis of peptide exchange catalysis by HLA-DMTwo distinct gamma interferon-inducible promoters of the major histocompatibility complex class II transactivator gene are differentially regulated by STAT1, interferon regulatory factor 1, and transforming growth factor betaExpression of endogenous peptide-major histocompatibility complex class II complexes derived from invariant chain-antigen fusion proteinsPromiscuous binding of invariant chain-derived CLIP peptide to distinct HLA-I molecules revealed in leukemic cells.Generation of MHC class II-peptide ligands for CD4 T-cell allorecognition of MHC class II molecules.Deficient antigen-presenting cell function in multiple genetic complementation groups of type II bare lymphocyte syndrome.Variation in vaccine response in normal populations.H2-DMalpha(-/-) mice show the importance of major histocompatibility complex-bound peptide in cardiac allograft rejectionFunctional genomics analyses of differential macaque peripheral blood mononuclear cell infections by human immunodeficiency virus-1 and simian immunodeficiency virusIn the absence of the invariant chain, HLA-DR molecules display a distinct array of peptides which is influenced by the presence or absence of HLA-DMThe relationship between immunodominance, DM editing, and the kinetic stability of MHC class II:peptide complexes.Right place, right time, right peptide: DO keeps DM focused.Conformational isomers of a peptide-class II major histocompatibility complex.The CLIP region of invariant chain plays a critical role in regulating major histocompatibility complex class II folding, transport, and peptide occupancyThe requirement for DM in class II-restricted antigen presentation and SDS-stable dimer formation is allele and species dependent.Binding of major histocompatibility complex class II to the invariant chain-derived peptide, CLIP, is regulated by allelic polymorphism in class II.Invariant chain cleavage and peptide loading in major histocompatibility complex class II vesicles.Presentation of a self-peptide for in vivo tolerance induction of CD4+ T cells is governed by a processing factor that maps to the class II region of the major histocompatibility complex locus.A novel antigen-processing-defective phenotype in major histocompatibility complex class II-positive CIITA transfectants is corrected by interferon-gamma.Major histocompatibility complex class II-associated peptides control the presentation of bacterial superantigens to T cells.Invariant chain and DM edit self-peptide presentation by major histocompatibility complex (MHC) class II molecules.Novel mutants define genes required for the expression of human histocompatibility leukocyte antigen DM: evidence for loci on human chromosome 6pA lysosomal targeting signal in the cytoplasmic tail of the beta chain directs HLA-DM to MHC class II compartments.
P2860
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P2860
HLA-DMA and -DMB genes are both required for MHC class II/peptide complex formation in antigen-presenting cells
description
1994 nî lūn-bûn
@nan
1994 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1994 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
name
HLA-DMA and -DMB genes are bot ...... on in antigen-presenting cells
@ast
HLA-DMA and -DMB genes are bot ...... on in antigen-presenting cells
@en
HLA-DMA and -DMB genes are bot ...... on in antigen-presenting cells
@nl
type
label
HLA-DMA and -DMB genes are bot ...... on in antigen-presenting cells
@ast
HLA-DMA and -DMB genes are bot ...... on in antigen-presenting cells
@en
HLA-DMA and -DMB genes are bot ...... on in antigen-presenting cells
@nl
prefLabel
HLA-DMA and -DMB genes are bot ...... on in antigen-presenting cells
@ast
HLA-DMA and -DMB genes are bot ...... on in antigen-presenting cells
@en
HLA-DMA and -DMB genes are bot ...... on in antigen-presenting cells
@nl
P2093
P356
P1433
P1476
HLA-DMA and -DMB genes are bot ...... on in antigen-presenting cells
@en
P2093
P2888
P356
10.1038/368554A0
P407
P577
1994-04-07T00:00:00Z
P6179
1051990759