Epigenetic inactivation of SFRP genes allows constitutive WNT signaling in colorectal cancer - Wikidata - wikimedia - TriplyDB

Epigenetic inactivation of SFRP genes allows constitutive WNT signaling in colorectal cancer

Epigenetic inactivation of SFRP genes allows constitutive WNT signaling in colorectal cancer

http://www.wikidata.org/entity/Q28251800

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Double strand breaks can initiate gene silencing and SIRT1-dependent onset of DNA methylation in an exogenous promoter CpG island Frequent loss of endothelin-3 (EDN3) expression due to epigenetic inactivation in human breast cancer Promoter hypermethylation of the SFRP2 gene is a high-frequent alteration and tumor-specific epigenetic marker in human breast cancer Wnt signaling pathways in urological cancers: past decades and still growing Prognostic relevance of Wnt-inhibitory factor-1 (WIF1) and Dickkopf-3 (DKK3) promoter methylation in human breast cancer Mutations of PIK3CA in gastric adenocarcinoma Epigenetic silencing of AXIN2 in colorectal carcinoma with microsatellite instability Frequent epigenetic inactivation of secreted frizzled-related protein 2 (SFRP2) by promoter methylation in human gastric cancer The SFRP family of WNT inhibitors function as novel tumor suppressor genes epigenetically silenced in medulloblastoma Frizzled-7 dictates three-dimensional organization of colorectal cancer cell carcinoids Suppressing Wnt signaling by the hedgehog pathway through sFRP-1 Sox7 Is an independent checkpoint for beta-catenin function in prostate and colon epithelial cells Down-regulation of frizzled-7 expression decreases survival, invasion and metastatic capabilities of colon cancer cells DACT3 is an epigenetic regulator of Wnt/beta-catenin signaling in colorectal cancer and is a therapeutic target of histone modifications Secreted Frizzled-related protein-1 is a negative regulator of androgen receptor activity in prostate cancer Epigenetic inactivation of the canonical Wnt antagonist SRY-box containing gene 17 in colorectal cancer Increased expression of secreted frizzled-related protein 4 in polycystic kidneys A decade of exploring the cancer epigenome - biological and translational implications An overview of epigenetics and chemoprevention Wnt/beta-catenin signaling: components, mechanisms, and diseases The Wnt antagonist sFRP1 is downregulated in premalignant large bowel adenomas The Wnt-dependent signaling pathways as target in oncology drug discovery Gli1, downregulated in colorectal cancers, inhibits proliferation of colon cancer cells involving Wnt signalling activation Frizzled7: A Promising Achilles' Heel for Targeting the Wnt Receptor Complex to Treat Cancer Development of anticancer agents targeting the Wnt/β-catenin signaling Epigenetic alterations of the Wnt signaling pathway in cancer: a mini review The dual role of the novel Wnt receptor tyrosine kinase, ROR2, in human carcinogenesis Crosstalk between Wnt/β-catenin and Hedgehog/Gli signaling pathways in colon cancer and implications for therapy Targeting the Wnt pathway in human cancers: therapeutic targeting with a focus on OMP-54F28 Frizzled homolog proteins, microRNAs and Wnt signaling in cancer A cryptic frizzled module in cell surface collagen 18 inhibits Wnt/beta-catenin signaling Sfrp controls apicobasal polarity and oriented cell division in developing gut epithelium Sulindac Inhibits Canonical Wnt Signaling by Blocking the PDZ Domain of the Protein Dishevelled Breast cancer epigenetics: from DNA methylation to microRNAs Epigenetic Therapeutics: A New Weapon in the War Against Cancer Wnt Drug Discovery: Weaving Through the Screens, Patents and Clinical Trials Epigenetic regulation of the intestinal epithelium Secreted Frizzled-related protein potentiation versus inhibition of Wnt3a/β-catenin signaling Loss of RALT/MIG-6 expression in ERBB2-amplified breast carcinomas enhances ErbB-2 oncogenic potency and favors resistance to Herceptin Epigenetic dysregulation of Wnt signaling pathway in multiple myeloma

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P2860

Epigenetic inactivation of SFRP genes allows constitutive WNT signaling in colorectal cancer

http://www.wikidata.org/entity/Q28251800

description

2004 nî lūn-bûn

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2004 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2004 թվականի ապրիլին հրատարակված գիտական հոդված

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2004年の論文

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2004年論文

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2004年論文

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2004年論文

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2004年論文

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2004年論文

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2004年论文

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name

Epigenetic inactivation of SFR ...... signaling in colorectal cancer

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Epigenetic inactivation of SFR ...... signaling in colorectal cancer

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Epigenetic inactivation of SFR ...... signaling in colorectal cancer

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type

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Epigenetic inactivation of SFR ...... signaling in colorectal cancer

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Epigenetic inactivation of SFR ...... signaling in colorectal cancer

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Epigenetic inactivation of SFR ...... signaling in colorectal cancer

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Epigenetic inactivation of SFR ...... signaling in colorectal cancer

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Epigenetic inactivation of SFR ...... signaling in colorectal cancer

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Epigenetic inactivation of SFR ...... signaling in colorectal cancer

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P1476

Epigenetic inactivation of SFR ...... signaling in colorectal cancer

@en

P2093

Bin Yang

http://www.w3.org/2001/XMLSchema#string

D Neil Watkins

http://www.w3.org/2001/XMLSchema#string

Hiromu Suzuki

http://www.w3.org/2001/XMLSchema#string

James G Herman

http://www.w3.org/2001/XMLSchema#string

Kam-Wing Jair

http://www.w3.org/2001/XMLSchema#string

Kohzoh Imai

http://www.w3.org/2001/XMLSchema#string

Kornel E Schuebel

http://www.w3.org/2001/XMLSchema#string

Manon Van Engeland

http://www.w3.org/2001/XMLSchema#string

Minoru Toyota

http://www.w3.org/2001/XMLSchema#string

Sanford D Markowitz

http://www.w3.org/2001/XMLSchema#string

P2888

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417-22

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scholarly article

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532976

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10.1038/NG1330

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4

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36

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2004-04-01T00:00:00Z

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8666172

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15034581

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P921

colorectal cancer