about
Investigating the structure and dynamics of the PIK3CA wild-type and H1047R oncogenic mutantThe p110δ structure: mechanisms for selectivity and potency of new PI(3)K inhibitorsHigh throughput chemical library screening identifies a novel p110-δ inhibitor that potentiates the anti-myeloma effect of bortezomibSomatic mutations in PI3Kalpha: structural basis for enzyme activation and drug designProtein Kinases as Drug Development Targets for Heart Disease TherapyPI3Kγ drives priming and survival of autoreactive CD4(+) T cells during experimental autoimmune encephalomyelitis.Prioritization of driver mutations in pancreatic cancer using cancer-specific high-throughput annotation of somatic mutations (CHASM).Resilience of biochemical activity in protein domains in the face of structural divergence.The enterococcal cytolysin synthetase has an unanticipated lipid kinase foldThe p110δ subunit of PI3K regulates bone marrow-derived eosinophil trafficking and airway eosinophilia in allergen-challenged mice.Combining mTOR Inhibitors with Chemotherapy and Other Targeted Therapies in Advanced Breast Cancer: Rationale, Clinical Experience, and Future Directionsp87 and p101 subunits are distinct regulators determining class IB phosphoinositide 3-kinase (PI3K) specificitySpecific PI3K isoform modulation in heart failure: lessons from transgenic mice.Isotype-specific inhibition of the phosphatidylinositol-3-kinase pathway in hematologic malignancies.Crossroads of PI3K and Rac pathways.Prostaglandin F2α stimulates PI3K/ERK/mTOR signaling and skeletal myotube hypertrophy.Class II but Not Second Class-Prospects for the Development of Class II PI3K Inhibitors.The p101 subunit of PI3Kγ restores activation by Gβ mutants deficient in stimulating p110γ.TGF-β1 induces human aortic vascular smooth muscle cell phenotype switch through PI3K/AKT/ID2 signaling.Conformational selection versus induced fit in kinases: the case of PI3K-γ.Introduction
P2860
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P2860
description
2009 nî lūn-bûn
@nan
2009 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Form and flexibility in phosphoinositide 3-kinases
@ast
Form and flexibility in phosphoinositide 3-kinases
@en
Form and flexibility in phosphoinositide 3-kinases
@nl
type
label
Form and flexibility in phosphoinositide 3-kinases
@ast
Form and flexibility in phosphoinositide 3-kinases
@en
Form and flexibility in phosphoinositide 3-kinases
@nl
prefLabel
Form and flexibility in phosphoinositide 3-kinases
@ast
Form and flexibility in phosphoinositide 3-kinases
@en
Form and flexibility in phosphoinositide 3-kinases
@nl
P2093
P3181
P356
P1476
Form and flexibility in phosphoinositide 3-kinases
@en
P2093
Alex Berndt
Simon Miller
Wai-Ching Hon
Xuxiao Zhang
P304
P3181
P356
10.1042/BST0370615
P407
P577
2009-08-01T00:00:00Z