Identification of MEN1 gene mutations in sporadic carcinoid tumors of the lung
about
Genome-wide analysis of menin binding provides insights into MEN1 tumorigenesis.The tumor suppressor protein menin interacts with NF-kappaB proteins and inhibits NF-kappaB-mediated transactivationMenin, the product of the MEN1 gene, is a nuclear proteinLung cancer cell migration is regulated via repressing growth factor PTN/RPTP β/ζ signaling by meninCellular and molecular biology of small cell lung cancer: an overviewMEN1 tumor-suppressor protein localizes to telomeres during meiosisA mouse model of multiple endocrine neoplasia, type 1, develops multiple endocrine tumorsMolecular profiling of clinical tissues specimens: feasibility and applicationsThe menin tumor suppressor protein is phosphorylated in response to DNA damageMolecular profiling of clinical tissue specimens: feasibility and applications.Sporadic endocrine tumours and their relationship to the hereditary endocrine neoplasia syndromes.Germ-line mutation analysis in patients with multiple endocrine neoplasia type 1 and related disordersMenin immunoreactivity in secretory granules of human pancreatic islet cellsBilateral adrenocortical carcinoma in a patient with multiple endocrine neoplasia type 1 (MEN1) and a novel mutation in the MEN1 gene.Population-based study of islet cell carcinoma.Parathyroid tumor development involves deregulation of homeobox genesDeletions of 11q22.3-q25 are associated with atypical lung carcinoids and poor clinical outcome.Analysis of sporadic neuroendocrine tumours of the enteropancreatic system by comparative genomic hybridisation.MEN1 mutations in Hürthle cell (oncocytic) thyroid carcinomaA report of a national mutation testing service for the MEN1 gene: clinical presentations and implications for mutation testing.Carcinoid--a comprehensive review.Of mice and MEN1: Insulinomas in a conditional mouse knockout.Safety and efficacy of everolimus in adult patients with neuroendocrine tumors.Mutations and allelic deletions of the MEN1 gene are associated with a subset of sporadic endocrine pancreatic and neuroendocrine tumors and not restricted to foregut neoplasms.Multiple leiomyomas of the esophagus, lung, and uterus in multiple endocrine neoplasia type 1.Typical and atypical carcinoid tumors of the lung are characterized by 11q deletions as detected by comparative genomic hybridization.Comparative genomic hybridization identifies loss of 18q22-qter as an early and specific event in tumorigenesis of midgut carcinoidsImpaired transforming growth factor-β (TGF-β) transcriptional activity and cell proliferation control of a menin in-frame deletion mutant associated with multiple endocrine neoplasia type 1 (MEN1).Pituitary tumors in patients with MEN1 syndrome.Molecular alterations in sporadic primary hyperparathyroidismTreatment of Zollinger-Ellison syndrome.Interplay between menin and K-Ras in regulating lung adenocarcinoma.Identification of somatic mutations of the MEN1 gene in sporadic endocrine tumours.Small Cell Lung Cancer: Can Recent Advances in Biology and Molecular Biology Be Translated into Improved Outcomes?Loss of MEN1 activates DNMT1 implicating DNA hypermethylation as a driver of MEN1 tumorigenesis.The molecular pathogenesis and management of bronchial carcinoids.Retrospective analysis of seventy-one patients with neuroendocrine tumor and review of the literature.Update on small cell carcinoma and its differentiation from squamous cell carcinoma and other non-small cell carcinomas.Neuroendocrine tumours--challenges in the diagnosis and classification of pulmonary neuroendocrine tumours.Recent advances in histogenesis research of lung neuroendocrine cancers: Evidence obtained from functional analyses of primitive neural/neuroendocrine cell-specific transcription factors.
P2860
Q21145267-DDA471E7-3ACD-4591-930A-8CC102E9F214Q24291618-3140F0B5-F5FB-45EC-A6FA-B25DDE1225DAQ24310070-55DA2490-7552-48BD-95D2-26793564A0CEQ24339039-827329CF-310E-4980-A8FA-335A4F0B4304Q26767029-9AB8E7AA-8A88-49AF-B301-B06FEBAA3F16Q28505590-A350518F-4EB1-44F4-820A-8129AEF0B27FQ28592210-46030E19-35DB-4AD4-9471-362947AB31C2Q30660744-50C7B0AE-3258-433B-B94A-739D4F581D75Q33802663-CE35512D-C51D-4506-B1E8-EC9FC8761573Q33883602-861B0AA9-CB07-4BBB-93A3-6BD960C74294Q33940347-1FA29CAA-79E3-4A92-9672-B830903A286BQ34386474-9D08B0CF-9F9B-4BCB-9184-326011296C81Q34514134-D1C96E42-803F-451E-84E8-43C8C0BBC76DQ34576778-3B1E1DF5-8A8B-48C8-AA11-77DE38C0E61CQ34693373-3B85E447-3ACF-4388-A98D-642519254A8FQ35098325-1B7866C8-8A23-454E-9D7E-2F3293280F99Q35167949-78A7A4B5-5BE6-4B23-B151-05C874163238Q35363122-B0B27602-83E1-4B43-B26D-C33C072A0D46Q35441859-DF422980-1CA6-458C-9CEF-F60E8183779AQ35446790-A3CFD3F8-6D4F-4313-A8C9-93CAA462102FQ35613499-88EE6950-9EEE-4539-AAAE-A1D4A5912A04Q35660901-FD05DED9-DE06-4DE3-AF7D-9E716C2540B1Q35669138-4F0F64F8-5AB9-436A-97F2-B5136BDF5C23Q35745261-887548C0-E86D-4548-BA0E-7E548CE11AB8Q35746773-BBD9B952-0C81-4470-8962-F2261A931A59Q35753449-5BE7A5E1-5398-4572-B885-7235C2B94526Q35842172-925B8351-5D4B-4A27-8365-9B6D28AB4E35Q35868179-1E00E5FC-8A09-448B-83B5-4BF7052FF566Q35895460-E4BC1AF0-D360-4D4D-BD77-E5D354A8C22DQ35910367-EBEC2038-BEB4-4046-B56C-121446CAE5A3Q36285347-D8C4D3B4-6377-431A-A07F-69804BD3D22EQ36407855-2FD8E4A2-4BC5-46F6-B948-D4561AA492E5Q36622047-55D4EF9F-95BE-426F-A763-C1C5354650FFQ36811784-AD38ADB4-58A1-463D-BC99-42EC7421845FQ37022247-8DD2C5CB-3BBB-46E4-9077-C9F5A8632A99Q37833109-5333525B-3B39-4086-B4FF-66AA232458C5Q37880665-1EAD9CAD-2DD9-4DD6-9EEF-4E20EB7D734AQ37972983-781128B1-3696-4BAA-BF34-91289E91D08AQ38107755-6788372B-0AA7-4B4E-9B75-68FF09D90C06Q38364517-DD856746-5E00-4537-807E-E96C4EE3BEF9
P2860
Identification of MEN1 gene mutations in sporadic carcinoid tumors of the lung
description
1997 nî lūn-bûn
@nan
1997 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
Identification of MEN1 gene mutations in sporadic carcinoid tumors of the lung
@ast
Identification of MEN1 gene mutations in sporadic carcinoid tumors of the lung
@en
Identification of MEN1 gene mutations in sporadic carcinoid tumors of the lung
@nl
type
label
Identification of MEN1 gene mutations in sporadic carcinoid tumors of the lung
@ast
Identification of MEN1 gene mutations in sporadic carcinoid tumors of the lung
@en
Identification of MEN1 gene mutations in sporadic carcinoid tumors of the lung
@nl
prefLabel
Identification of MEN1 gene mutations in sporadic carcinoid tumors of the lung
@ast
Identification of MEN1 gene mutations in sporadic carcinoid tumors of the lung
@en
Identification of MEN1 gene mutations in sporadic carcinoid tumors of the lung
@nl
P2093
P356
P1476
Identification of MEN1 gene mutations in sporadic carcinoid tumors of the lung
@en
P2093
A M Spiegel
E Brambilla
F S Collins
I A Lubensky
J I Swalwell
J S Crabtree
L A Liotta
L V Debelenko
P304
P356
10.1093/HMG/6.13.2285
P407
P577
1997-12-01T00:00:00Z