The MNB/DYRK1A protein kinase: genetic and biochemical properties
about
Genome-wide association study identifies single nucleotide polymorphism in DYRK1A associated with replication of HIV-1 in monocyte-derived macrophagesDyrk1A potentiates steroid hormone-induced transcription via the chromatin remodeling factor Arip4DYRK1A enhances the mitogen-activated protein kinase cascade in PC12 cells by forming a complex with Ras, B-Raf, and MEK1.dDYRK2 and Minibrain interact with the chromatin remodelling factors SNR1 and TRX.Characterization of the human DYRK1A promoter and its regulation by the transcription factor E2F1.Impaired spatial learning strategies and novel object recognition in mice haploinsufficient for the dual specificity tyrosine-regulated kinase-1A (Dyrk1A).Structural analysis of pathogenic mutations in the DYRK1A gene in patients with developmental disorders.Fruit flies and intellectual disability.The role of DYRK1A in neurodegenerative diseases.Mitogen-activated protein kinase kinase 1 (MEK1) stabilizes MyoD through direct phosphorylation at tyrosine 156 during myogenic differentiation.Transient expression of Mnb/Dyrk1a couples cell cycle exit and differentiation of neuronal precursors by inducing p27KIP1 expression and suppressing NOTCH signaling.Ten new cases further delineate the syndromic intellectual disability phenotype caused by mutations in DYRK1A.DYRK1A-dosage imbalance perturbs NRSF/REST levels, deregulating pluripotency and embryonic stem cell fate in Down syndromeIncreased dosage of Dyrk1A alters alternative splicing factor (ASF)-regulated alternative splicing of tau in Down syndromeAnticancer alkaloid lamellarins inhibit protein kinases.The molecular chaperone TRiC/CCT binds to the Trp-Asp 40 (WD40) repeat protein WDR68 and promotes its folding, protein kinase DYRK1A binding, and nuclear accumulation.Overexpression of DYRK1A, a Down Syndrome Candidate gene, Impairs Primordial Germ Cells Maintenance and Migration in zebrafish.Emerging Roles of DYRK Kinases in Embryogenesis and Hedgehog Pathway Control.
P2860
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P2860
The MNB/DYRK1A protein kinase: genetic and biochemical properties
description
2003 nî lūn-bûn
@nan
2003 թուականին հրատարակուած գիտական յօդուած
@hyw
2003 թվականին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
The MNB/DYRK1A protein kinase: genetic and biochemical properties
@ast
The MNB/DYRK1A protein kinase: genetic and biochemical properties
@en
The MNB/DYRK1A protein kinase: genetic and biochemical properties
@nl
type
label
The MNB/DYRK1A protein kinase: genetic and biochemical properties
@ast
The MNB/DYRK1A protein kinase: genetic and biochemical properties
@en
The MNB/DYRK1A protein kinase: genetic and biochemical properties
@nl
prefLabel
The MNB/DYRK1A protein kinase: genetic and biochemical properties
@ast
The MNB/DYRK1A protein kinase: genetic and biochemical properties
@en
The MNB/DYRK1A protein kinase: genetic and biochemical properties
@nl
P2093
P1476
The MNB/DYRK1A protein kinase: genetic and biochemical properties
@en
P2093
F J Tejedor
J Galceran
K de Graaf
P304
P407
P577
2003-01-01T00:00:00Z