Integrin cytoplasmic domains: mediators of cytoskeletal linkages and extra- and intracellular initiated transmembrane signaling
about
The p16(INK4a) tumour suppressor protein inhibits alphavbeta3 integrin-mediated cell spreading on vitronectin by blocking PKC-dependent localization of alphavbeta3 to focal contacts.Melusin is a new muscle-specific interactor for beta(1) integrin cytoplasmic domainBeta 2 integrin-dependent protein tyrosine phosphorylation and activation of the FGR protein tyrosine kinase in human neutrophilsSrc kinase associates with a member of a distinct subfamily of protein-tyrosine phosphatases containing an ezrin-like domainICAP-1, a novel beta1 integrin cytoplasmic domain-associated protein, binds to a conserved and functionally important NPXY sequence motif of beta1 integrinEpisialin (MUC1) overexpression inhibits integrin-mediated cell adhesion to extracellular matrix componentsCalcium-dependent signaling pathways in T cells. Potential role of calpain, protein tyrosine phosphatase 1b, and p130Cas in integrin-mediated signaling eventsBeta 3-endonexin, a novel polypeptide that interacts specifically with the cytoplasmic tail of the integrin beta 3 subunitMonocyte cells and cancer cells express novel paxillin isoforms with different binding properties to focal adhesion proteinsIdentification, purification, and characterization of a zyxin-related protein that binds the focal adhesion and microfilament protein VASP (vasodilator-stimulated phosphoprotein)Focal adhesion kinase and paxillin bind to peptides mimicking beta integrin cytoplasmic domains.Cytohesin-1 regulates beta-2 integrin-mediated adhesion through both ARF-GEF function and interaction with LFA-1A selective cyclic integrin antagonist blocks the integrin receptors alphavbeta3 and alphavbeta5 and inhibits retinal pigment epithelium cell attachment, migration and invasionActin cytoskeletal association of cytohesin-1 is regulated by specific phosphorylation of its carboxyl-terminal polybasic domainA fragment of paxillin binds the alpha 4 integrin cytoplasmic domain (tail) and selectively inhibits alpha 4-mediated cell migrationPhosphorylation of the integrin alpha 4 cytoplasmic domain regulates paxillin bindingA novel structural variant of the human beta 4 integrin cDNABeta 1D integrin displaces the beta 1A isoform in striated muscles: localization at junctional structures and signaling potential in nonmuscle cellsExpression of beta 1B integrin isoform in CHO cells results in a dominant negative effect on cell adhesion and motilityThe role of conserved amino acid motifs within the integrin beta3 cytoplasmic domain in triggering focal adhesion kinase phosphorylationThe role of endocytosis in regulating L1-mediated adhesionCalmodulin binds to specific sequences in the cytoplasmic domain of C-CAM and down-regulates C-CAM self-associationThe heat-stable antigen can alter very late antigen 4-mediated adhesionCleavage of focal adhesion kinase by caspases during apoptosisIntegrin function: molecular hierarchies of cytoskeletal and signaling moleculesDegraded collagen fragments promote rapid disassembly of smooth muscle focal adhesions that correlates with cleavage of pp125(FAK), paxillin, and talinQuantitative changes in integrin and focal adhesion signaling regulate myoblast cell cycle withdrawal.Inhibition of pp125FAK in cultured fibroblasts results in apoptosis.Protein kinase C regulates alpha v beta 5-dependent cytoskeletal associations and focal adhesion kinase phosphorylation.Regulation of the pp72syk protein tyrosine kinase by platelet integrin alpha IIb beta 3Molecular cloning and developmental expression of the Xenopus homolog of integrin alpha 4.The role of the dynamics of focal adhesion kinase in the mechanotaxis of endothelial cells.The critical cytoplasmic regions of the alphaL/beta2 integrin in Rap1-induced adhesion and migration.Phosphorylation of a conserved integrin alpha 3 QPSXXE motif regulates signaling, motility, and cytoskeletal engagement.Rhodocytin induces platelet aggregation by interacting with glycoprotein Ia/IIa (GPIa/IIa, Integrin alpha 2beta 1). Involvement of GPIa/IIa-associated src and protein tyrosine phosphorylation.Injury and EGF mediate the expression of alpha6beta4 integrin subunits in corneal epithelium.PTEN gene and integrin signaling in cancer.Biophysical integration of effects of epidermal growth factor and fibronectin on fibroblast migration.Molecular biology and anatomy of Drosophila olfactory associative learning.Engineering of vascular ingrowth matrices: are protein domains an alternative to peptides?
P2860
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P2860
Integrin cytoplasmic domains: mediators of cytoskeletal linkages and extra- and intracellular initiated transmembrane signaling
description
1993 nî lūn-bûn
@nan
1993 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1993 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
name
Integrin cytoplasmic domains: ...... tiated transmembrane signaling
@ast
Integrin cytoplasmic domains: ...... tiated transmembrane signaling
@en
Integrin cytoplasmic domains: ...... tiated transmembrane signaling
@nl
type
label
Integrin cytoplasmic domains: ...... tiated transmembrane signaling
@ast
Integrin cytoplasmic domains: ...... tiated transmembrane signaling
@en
Integrin cytoplasmic domains: ...... tiated transmembrane signaling
@nl
prefLabel
Integrin cytoplasmic domains: ...... tiated transmembrane signaling
@ast
Integrin cytoplasmic domains: ...... tiated transmembrane signaling
@en
Integrin cytoplasmic domains: ...... tiated transmembrane signaling
@nl
P1476
Integrin cytoplasmic domains: ...... tiated transmembrane signaling
@en
P2093
A F Horwitz
S K Sastry
P304
P356
10.1016/0955-0674(93)90031-K
P407
P577
1993-10-01T00:00:00Z