Small molecule inhibition of group I p21-activated kinases in breast cancer induces apoptosis and potentiates the activity of microtubule stabilizing agents.
about
p21-activated kinase group II small compound inhibitor GNE-2861 perturbs estrogen receptor alpha signaling and restores tamoxifen-sensitivity in breast cancer cellsP21-Activated Kinase Inhibitors FRAX486 and IPA3: Inhibition of Prostate Stromal Cell Growth and Effects on Smooth Muscle Contraction in the Human Prostatep27Kip1 promotes invadopodia turnover and invasion through the regulation of the PAK1/Cortactin pathway.Design of Selective PAK1 Inhibitor G-5555: Improving Properties by Employing an Unorthodox Low-pK a Polar Moiety.Proteogenomics connects somatic mutations to signalling in breast cancer.The Group I Pak inhibitor Frax-1036 sensitizes 11q13-amplified ovarian cancer cells to the cytotoxic effects of Rottlerin.Anti-tumor efficacy of BEZ235 is complemented by its anti-angiogenic effects via downregulation of PI3K-mTOR-HIF1alpha signaling in HER2-defined breast cancers.Study on the expression of PAK4 and P54 protein in breast cancer.p21-activated kinase 1 (PAK1) expression correlates with prognosis in solid tumors: A systematic review and meta-analysisTargeting PAK1.Structure, biochemistry, and biology of PAK kinases.Suppression of RAC1-driven malignant melanoma by group A PAK inhibitors.Inhibition of neuroblastoma proliferation by PF-3758309, a small-molecule inhibitor that targets p21-activated kinase 4.Rho GTPases: RAC1 polymorphisms affected platinum-based chemotherapy toxicity in lung cancer patients.Group I Paks are essential for epithelial- mesenchymal transition in an Apc-driven model of colorectal cancer
P2860
Q28269662-DC8A9DD2-8131-48DC-8094-C03B3092D203Q28551296-7AEE288F-2977-4178-AC32-269715460D54Q33554593-7ADC282B-774E-498A-AC8D-A7FA43BF0CA3Q34506833-A05BB5D4-53B9-4DDD-B9B9-ED8EA77D47ADQ36037203-2E3FA0D7-C5B2-4A38-9356-3E0AF0CE45FEQ36079783-492C2C67-E47D-4D6F-A199-9D13606D3DE7Q36879470-F17A0FA6-631A-49A2-98EB-18B586F51338Q37001333-E91A46D6-DACC-4DAD-9819-11FDBAF60CC0Q37317276-DB67467B-705C-4027-A481-C1BA0F5ED7E5Q38757029-8B786CEC-7A6D-4FE9-835D-11F26C0784E0Q38779105-498F6C88-374A-4DC4-B0A3-EB7CC503EE55Q47742602-470431F3-FECC-47F4-8036-6414E72BDC77Q48626677-9228BB47-86E1-46EB-8C1C-385B21094B8FQ51703834-229EACE3-0CFB-45E6-9858-7825A3713BE6Q57980063-DACD7FE4-C5C7-42C1-9DF9-85C3B1C7CD4A
P2860
Small molecule inhibition of group I p21-activated kinases in breast cancer induces apoptosis and potentiates the activity of microtubule stabilizing agents.
description
2015 nî lūn-bûn
@nan
2015 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
name
Small molecule inhibition of g ...... microtubule stabilizing agents
@nl
Small molecule inhibition of g ...... icrotubule stabilizing agents.
@ast
Small molecule inhibition of g ...... icrotubule stabilizing agents.
@en
type
label
Small molecule inhibition of g ...... microtubule stabilizing agents
@nl
Small molecule inhibition of g ...... icrotubule stabilizing agents.
@ast
Small molecule inhibition of g ...... icrotubule stabilizing agents.
@en
prefLabel
Small molecule inhibition of g ...... microtubule stabilizing agents
@nl
Small molecule inhibition of g ...... icrotubule stabilizing agents.
@ast
Small molecule inhibition of g ...... icrotubule stabilizing agents.
@en
P2093
P2860
P50
P3181
P1476
Small molecule inhibition of g ...... icrotubule stabilizing agents.
@en
P2093
Adrian M Jubb
Cameron Pitt
Christine K Cheng
Christy C Ong
David A Campbell
Hartmut Koeppen
Joachim Rudolph
John C McKew
Klaus P Hoeflich
Laura Strickland
P2860
P2888
P3181
P356
10.1186/S13058-015-0564-5
P407
P50
P577
2015-04-23T00:00:00Z
P5875
P6179
1011586271