Dynein light chain 1, a p21-activated kinase 1-interacting substrate, promotes cancerous phenotypes
about
CRIPak, a novel endogenous Pak1 inhibitorFunctional regulation of oestrogen receptor pathway by the dynein light chain 1.Dynein light chain LC8 negatively regulates NF-kappaB through the redox-dependent interaction with IkappaBalphaEssential role of KIBRA in co-activator function of dynein light chain 1 in mammalian cellsThe MEK1 scaffolding protein MP1 regulates cell spreading by integrating PAK1 and Rho signals.Functional and biological properties of the nuclear receptor coregulator PELP1/MNARp21-activated kinase signaling in breast cancerGenetic analysis of the cytoplasmic dynein subunit families.The role of p21-activated kinases in hepatocellular carcinoma metastasisStructural and thermodynamic characterization of a cytoplasmic dynein light chain intermediate chain complexBiochemical and Structural Characterization of the Pak1-LC8 InteractionThe Interplay of Ligand Binding and Quaternary Structure in the Diverse Interactions of Dynein Light Chain LC8Directed Evolution Reveals the Binding Motif Preference of the LC8/DYNLL Hub Protein and Predicts Large Numbers of Novel Binders in the Human ProteomeFunctional interaction between dynein light chain and intermediate chain is required for mitotic spindle positioning.JAK2 tyrosine kinase phosphorylates PAK1 and regulates PAK1 activity and functionsSmall molecule inhibition of group I p21-activated kinases in breast cancer induces apoptosis and potentiates the activity of microtubule stabilizing agents.Molecular pathways: targeting p21-activated kinase 1 signaling in cancer--opportunities, challenges, and limitationsPELP1: A novel therapeutic target for hormonal cancersFunctional implications of altered subcellular localization of PELP1 in breast cancer cells.PAK as a therapeutic target in gastric cancerCyclin-dependent kinase-mediated phosphorylation plays a critical role in the oncogenic functions of PELP1MicroRNA-7, a homeobox D10 target, inhibits p21-activated kinase 1 and regulates its functionsPhosphorylation-dependent regulation of stability and transforming potential of ETS transcriptional factor ESE-1 by p21-activated kinase 1Significance of ER-Src axis in hormonal therapy resistanceOncogenic potential of the nuclear receptor coregulator proline-, glutamic acid-, leucine-rich protein 1/modulator of the nongenomic actions of the estrogen receptorPAK signalling during the development and progression of cancerDynein light chain regulates axonal trafficking and synaptic levels of BassoonPAK1-Nck regulates cyclin D1 promoter activity in response to prolactinA myosin-Va tail fragment sequesters dynein light chains leading to apoptosis in melanoma cells.The exchange factor and diacylglycerol receptor RasGRP3 interacts with dynein light chain 1 through its C-terminal domain.Interaction with LC8 is required for Pak1 nuclear import and is indispensable for zebrafish developmentPak2 is required for actin cytoskeleton remodeling, TCR signaling, and normal thymocyte development and maturation.Structural, thermodynamic, and kinetic effects of a phosphomimetic mutation in dynein light chain LC8.Regulation of aromatase induction by nuclear receptor coregulator PELP1Identification and functional significance of genes regulated by structurally different histone deacetylase inhibitors.Function of RasGRP3 in the formation and progression of human breast cancerArpc1b, a centrosomal protein, is both an activator and substrate of Aurora A.The dynamic interaction of AMBRA1 with the dynein motor complex regulates mammalian autophagy.Affinity, avidity, and kinetics of target sequence binding to LC8 dynein light chain isoforms.Cyclic AMP inhibits p38 activation via CREB-induced dynein light chain.
P2860
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P2860
Dynein light chain 1, a p21-activated kinase 1-interacting substrate, promotes cancerous phenotypes
description
2004 nî lūn-bûn
@nan
2004 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Dynein light chain 1, a p21-ac ...... promotes cancerous phenotypes
@ast
Dynein light chain 1, a p21-ac ...... promotes cancerous phenotypes
@en
Dynein light chain 1, a p21-ac ...... promotes cancerous phenotypes
@nl
type
label
Dynein light chain 1, a p21-ac ...... promotes cancerous phenotypes
@ast
Dynein light chain 1, a p21-ac ...... promotes cancerous phenotypes
@en
Dynein light chain 1, a p21-ac ...... promotes cancerous phenotypes
@nl
prefLabel
Dynein light chain 1, a p21-ac ...... promotes cancerous phenotypes
@ast
Dynein light chain 1, a p21-ac ...... promotes cancerous phenotypes
@en
Dynein light chain 1, a p21-ac ...... promotes cancerous phenotypes
@nl
P2093
P1433
P1476
Dynein light chain 1, a p21-ac ...... promotes cancerous phenotypes
@en
P2093
Aysegul A Sahin
Diep Nguyen
Petra den Hollander
Rakesh Kumar
Ratna K Vadlamudi
Rozita Bagheri-Yarmand
Seetharaman Balasenthil
Zhibo Yang
P304
P356
10.1016/J.CCR.2004.05.022
P407
P577
2004-06-01T00:00:00Z