Large conformational changes in MutS during DNA scanning, mismatch recognition and repair signalling.
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Single-molecule views of MutS on mismatched DNA.An Efficient Site-Specific Method for Irreversible Covalent Labeling of Proteins with a Fluorophore.Postreplicative mismatch repair.Single-molecule imaging reveals target-search mechanisms during DNA mismatch repair.Mismatch repair protein hMSH2-hMSH6 recognizes mismatches and forms sliding clamps within a D-loop recombination intermediateEvolutionary Covariance Combined with Molecular Dynamics Predicts a Framework for Allostery in the MutS DNA Mismatch Repair Protein.A 'Semi-Protected Oligonucleotide Recombination' Assay for DNA Mismatch Repair in vivo Suggests Different Modes of Repair for Lagging Strand Mismatches.Eukaryotic Mismatch Repair in Relation to DNA ReplicationSingle molecule studies of DNA mismatch repair.Mismatch repair during homologous and homeologous recombinationIs thymidine glycol containing DNA a substrate of E. coli DNA mismatch repair system?Structural basis of asymmetric DNA methylation and ATP-triggered long-range diffusion by EcoP15IMutations in the nucleotide binding and hydrolysis domains of Helicobacter pylori MutS2 lead to altered biochemical activities and inactivation of its in vivo function.MutL traps MutS at a DNA mismatch.Atomic force microscopy captures the initiation of methyl-directed DNA mismatch repair.Single-molecule motions and interactions in live cells reveal target search dynamics in mismatch repair.Engineered disulfide-forming amino acid substitutions interfere with a conformational change in the mismatch recognition complex Msh2-Msh6 required for mismatch repair.Roles for mismatch repair family proteins in promoting meiotic crossing over.Dynamic DNA binding licenses a repair factor to bypass roadblocks in search of DNA lesions.Dual daughter strand incision is processive and increases the efficiency of DNA mismatch repair.DNA conformations in mismatch repair probed in solution by X-ray scattering from gold nanocrystals.Destabilization of the MutSα's protein-protein interface due to binding to the DNA adduct induced by anticancer agent carboplatin via molecular dynamics simulations.Visualizing the Path of DNA through Proteins Using DREEM Imaging.Modern aspects of the structural and functional organization of the DNA mismatch repair system.Mismatch binding, ADP-ATP exchange and intramolecular signaling during mismatch repair.Single-Molecule FRET to Measure Conformational Dynamics of DNA Mismatch Repair Proteins.Apparent Epigenetic Meiotic Double-Strand-Break Disparity in Saccharomyces cerevisiae: A Meta-Analysis.The helicase-like domains of type III restriction enzymes trigger long-range diffusion along DNAATP binding and hydrolysis by Saccharomyces cerevisiae Msh2-Msh3 are differentially modulated by mismatch and double-strand break repair DNA substrates.Distinct requirements within the Msh3 nucleotide binding pocket for mismatch and double-strand break repair.DNA mutation motifs in the genes associated with inherited diseases.MutS/MutL crystal structure reveals that the MutS sliding clamp loads MutL onto DNA.Switching roles for a helicase.Slow conformational changes in MutS and DNA direct ordered transitions between mismatch search, recognition and signaling of DNA repair.Using Atomic Force Microscopy to Characterize the Conformational Properties of Proteins and Protein-DNA Complexes That Carry Out DNA Repair.Interaction studies of muts and mutl with DNA containing the major cisplatin lesion and its mismatched counterpart under equilibrium and nonequilibrium conditions.Mechanism of formation of a toroid around DNA by the mismatch sensor protein.Visualizing correlated motion with HDBSCAN clustering.MutS stimulates the endonuclease activity of MutL in an ATP-hydrolysis-dependent manner.Coordinated protein and DNA conformational changes govern mismatch repair initiation by MutS
P2860
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P2860
Large conformational changes in MutS during DNA scanning, mismatch recognition and repair signalling.
description
2012 nî lūn-bûn
@nan
2012 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Large conformational changes i ...... ognition and repair signalling
@nl
Large conformational changes i ...... gnition and repair signalling.
@ast
Large conformational changes i ...... gnition and repair signalling.
@en
type
label
Large conformational changes i ...... ognition and repair signalling
@nl
Large conformational changes i ...... gnition and repair signalling.
@ast
Large conformational changes i ...... gnition and repair signalling.
@en
prefLabel
Large conformational changes i ...... ognition and repair signalling
@nl
Large conformational changes i ...... gnition and repair signalling.
@ast
Large conformational changes i ...... gnition and repair signalling.
@en
P2093
P2860
P3181
P356
P1433
P1476
Large conformational changes i ...... gnition and repair signalling.
@en
P2093
Anushi Sharma
Credle Harris
Dorothy A Erie
Keith R Weninger
Manju M Hingorani
Vanessa C DeRocco
P2860
P304
P3181
P356
10.1038/EMBOJ.2012.95
P407
P577
2012-04-13T00:00:00Z