Composite active site of an ABC ATPase: MutS uses ATP to verify mismatch recognition and authorize DNA repair
about
hMutSalpha forms an ATP-dependent complex with hMutLalpha and hMutLbeta on DNA.Differential specificities and simultaneous occupancy of human MutSalpha nucleotide binding sitesMechanism of mismatch recognition revealed by human MutSĪ² bound to unpaired DNA loopsFunctional studies and homology modeling of Msh2-Msh3 predict that mispair recognition involves DNA bending and strand separationDNA mismatch repair: molecular mechanism, cancer, and ageingN-terminus of hMLH1 confers interaction of hMutLalpha and hMutLbeta with hMutSalphaRecognition and binding of mismatch repair proteins at an oncogenic hot spotSingle-molecule views of MutS on mismatched DNA.New insights and challenges in mismatch repair: getting over the chromatin hurdleStructure and function of the N-terminal 40 kDa fragment of human PMS2: a monomeric GHL ATPase.The alternating ATPase domains of MutS control DNA mismatch repairCrystal structure and biochemical analysis of the MutS.ADP.beryllium fluoride complex suggests a conserved mechanism for ATP interactions in mismatch repairInsights into finding a mismatch through the structure of a mispaired DNA bound by a rhodium intercalatorStructural conservation of RecF and Rad50: implications for DNA recognition and RecF functionEscherichia coli MutS tetramerization domain structure reveals that stable dimers but not tetramers are essential for DNA mismatch repair in vivoCrystal Structure of Bacillus stearothermophilus UvrA Provides Insight into ATP-Modulated Dimerization, UvrB Interaction, and DNA BindingX-ray structure of the complete ABC enzyme ABCE1 from Pyrococcus abyssiMagnesium Coordination Controls the Molecular Switch Function of DNA Mismatch Repair Protein MutSUsing stable MutS dimers and tetramers to quantitatively analyze DNA mismatch recognition and sliding clamp formation.Postreplicative mismatch repair.Saccharomyces cerevisiae Msh2-Msh3 acts in repair of base-base mispairsNew insights into the mechanism of DNA mismatch repairDNA mismatch repair and mutation avoidance pathwaysLarge conformational changes in MutS during DNA scanning, mismatch recognition and repair signalling.Structural, molecular and cellular functions of MSH2 and MSH6 during DNA mismatch repair, damage signaling and other noncanonical activitiesDNA mismatch repair in eukaryotes and bacteriaDNA repair mechanisms and the bypass of DNA damage in Saccharomyces cerevisiaeMechanism of MutS searching for DNA mismatches and signaling repairThe discovery, function and development of the variable number tandem repeats in different Mycobacterium species.A unique horizontal gene transfer event has provided the octocoral mitochondrial genome with an active mismatch repair gene that has potential for an unusual self-contained function.Chemical trapping of the dynamic MutS-MutL complex formed in DNA mismatch repair in Escherichia coli.Single-molecule imaging reveals target-search mechanisms during DNA mismatch repair.Evolutionary Covariance Combined with Molecular Dynamics Predicts a Framework for Allostery in the MutS DNA Mismatch Repair Protein.Guinier peak analysis for visual and automated inspection of small-angle X-ray scattering data.Regulation of replication protein A functions in DNA mismatch repair by phosphorylation.A multi-step pathway for the establishment of sister chromatid cohesion.Adenosine triphosphate stimulates Aquifex aeolicus MutL endonuclease activity.Interaction of MutS and Vsr: some dominant-negative mutS mutations that disable methyladenine-directed mismatch repair are active in very-short-patch repair.Xenopus Cdc6 performs separate functions in initiating DNA replicationSaccharomyces cerevisiae Msh2-Msh6 DNA binding kinetics reveal a mechanism of targeting sites for DNA mismatch repair.
P2860
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P2860
Composite active site of an ABC ATPase: MutS uses ATP to verify mismatch recognition and authorize DNA repair
description
2001 nĆ® lÅ«n-bĆ»n
@nan
2001 Õ©ÕøÖÕ”ÕÆÕ”Õ¶Õ« Õ
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@hyw
2001 Õ©Õ¾Õ”ÕÆÕ”Õ¶Õ« Õ°ÕøÖÕ¶Õ¾Õ”ÖÕ«Õ¶ Õ°ÖÕ”ÕæÕ”ÖÕ”ÕÆÕ¾Õ”Õ® Õ£Õ«ÕæÕ”ÕÆÕ”Õ¶ Õ°ÕøÕ¤Õ¾Õ”Õ®
@hy
2001幓ć®č«ę
@ja
2001幓č«ę
@yue
2001幓č«ę
@zh-hant
2001幓č«ę
@zh-hk
2001幓č«ę
@zh-mo
2001幓č«ę
@zh-tw
2001幓č®ŗę
@wuu
name
Composite active site of an AB ...... ition and authorize DNA repair
@ast
Composite active site of an AB ...... ition and authorize DNA repair
@en
Composite active site of an AB ...... ition and authorize DNA repair
@nl
type
label
Composite active site of an AB ...... ition and authorize DNA repair
@ast
Composite active site of an AB ...... ition and authorize DNA repair
@en
Composite active site of an AB ...... ition and authorize DNA repair
@nl
prefLabel
Composite active site of an AB ...... ition and authorize DNA repair
@ast
Composite active site of an AB ...... ition and authorize DNA repair
@en
Composite active site of an AB ...... ition and authorize DNA repair
@nl
P2093
P3181
P1433
P1476
Composite active site of an AB ...... ition and authorize DNA repair
@en
P2093
P3181
P356
10.1016/S1097-2765(01)00149-6
P50
P577
2001-01-01T00:00:00Z