X-ray crystal structures of the estrogen-related receptor-gamma ligand binding domain in three functional states reveal the molecular basis of small molecule regulation - Wikidata - wikimedia - TriplyDB

X-ray crystal structures of the estrogen-related receptor-gamma ligand binding domain in three functional states reveal the molecular basis of small molecule regulation

X-ray crystal structures of the estrogen-related receptor-gamma ligand binding domain in three functional states reveal the molecular basis of small molecule regulation

http://www.wikidata.org/entity/Q28264769

about

Direct evidence revealing structural elements essential for the high binding ability of bisphenol A to human estrogen-related receptor-gamma Identification of heme as the ligand for the orphan nuclear receptors REV-ERBalpha and REV-ERBbeta.Estrogen-related receptor β (ERRβ) - renaissance receptor or receptor renaissance?Crystal structure of human estrogen-related receptor alpha in complex with a synthetic inverse agonist reveals its novel molecular mechanism Structure of Rev-erbα bound to N-CoR reveals a unique mechanism of nuclear receptor–co-repressor interaction Structural Basis for Retinoic X Receptor Repression on the Tetramer Ligand dissociation from estrogen receptor is mediated by receptor dimerization: evidence from molecular dynamics simulations Phosphorylation-dependent sumoylation regulates estrogen-related receptor-alpha and -gamma transcriptional activity through a synergy control motif.Estrogen-related receptor γ serves a role in blood pressure homeostasis during pregnancy Importance of the Sequence-Directed DNA Shape for Specific Binding Site Recognition by the Estrogen-Related Receptor.A characteristic back support structure in the bisphenol A-binding pocket in the human nuclear receptor ERRγ.Effects of the hydroxyl group on phenyl based ligand/ERRγ protein binding.Melanoma antigen-A11 (MAGE-A11) enhances transcriptional activity by linking androgen receptor dimers.Cartilage-specific overexpression of ERRγ results in Chondrodysplasia and reduced chondrocyte proliferation.A Novel ESRRB Deletion Is a Rare Cause of Autosomal Recessive Nonsyndromic Hearing Impairment among Pakistani Families Orphan nuclear receptor estrogen-related receptor γ (ERRγ) is key regulator of hepatic gluconeogenesis.ERRβ splice variants differentially regulate cell cycle progression.The NR3B subgroup: an ovERRview Involvement of estrogen-related receptors in transcriptional response to hypoxia and growth of solid tumors.Selectively targeting prostate cancer with antiandrogen equipped histone deacetylase inhibitors.Antimitotic activity of DY131 and the estrogen-related receptor beta 2 (ERRβ2) splice variant in breast cancer.Orphan nuclear receptors as targets for drug development.Nuclear hormone receptor co-repressors: structure and function.An evolving understanding of nuclear receptor coregulator proteins.Orphan nuclear receptor ERRγ is a key regulator of human fibrinogen gene expression.Esrrg functions in early branch generation of the ureteric bud and is essential for normal development of the renal papilla.Estrogen-related receptor gamma is a key regulator of muscle mitochondrial activity and oxidative capacity On the intractability of estrogen-related receptor alpha as a target for activation by small molecules.Estrogen induces estrogen-related receptor alpha gene expression and chromatin structural changes in estrogen receptor (ER)-positive and ER-negative breast cancer cells.Stabilization of protein-protein interactions in drug discovery.Esrrb, an estrogen-related receptor involved in early development, pluripotency, and reprogramming.Binding mode prediction and MD/MMPBSA-based free energy ranking for agonists of REV-ERBα/NCoR.Ternary complex of human RORγ ligand-binding domain, inverse agonist and SMRT peptide shows a unique mechanism of corepressor recruitment.Divergent regulation of the Osteopontin promoter by the estrogen receptor-related receptors is isoform- and cell context dependent.Distinct mechanisms of endocrine disruption of DDT-related pesticides toward estrogen receptor α and estrogen-related receptor γ.Computer-aided design and synthesis of tetra-aryl-substituted alkenes and their bioevaluation as a selective modulator of estrogen-related receptor γ.

P2860

Q24652507-3EE63E59-4373-45C1-8C16-CE26B660D2A0 Q24655134-334F54B1-1418-4BF2-A701-C7FC8E3A2321 Q26738295-95E40E22-62A5-4072-9801-83C471EC3DEA Q27645400-87FB3587-0FEF-4233-A9CC-05F52B957E31 Q27662827-056FEE9E-F001-4E47-8196-62C92D413CC2 Q27668012-82C903B3-04F2-4C30-8A57-10A3C444B3B3 Q33642693-5EB99B7F-55AE-49DC-A038-C8EBEFE5FA9A Q33643260-61FCEC7A-F66C-462B-980F-6BFFD6B26335 Q33701412-C25DE443-EEEE-4E91-9C58-49F5825D087E Q33813823-E0A81DF4-3304-4D01-B347-97DC0404979A Q33825849-0C3FFF3B-816B-43AE-8F3B-C95C404E6BB1 Q34065929-C02522E5-FF43-49CE-BC82-78D646D71787 Q34313140-D3FFE723-59AF-45AE-9BC6-C17AB9BA9BCF Q35069637-BFE61A35-CAFE-4065-9090-BCBF487929BF Q35910206-A2CB333B-DE36-41D6-87F7-B628C47CD698 Q36052342-E9510628-794E-414B-A7E2-40F75AF2B9CF Q36187539-381B16F9-5208-4405-AB59-3B6AFA5BBC3E Q36238317-0737F336-1FD5-4FEE-AA87-FC7769994241 Q36693861-C1575374-F101-4B39-99CA-9339782035B8 Q37332601-CE6D492E-CDA9-48E2-8894-0C6605D24993 Q37565093-A124C16E-5E8B-4B83-B65B-A13F7E2D4B16 Q37725708-0FCC9D57-2DD3-456E-92BA-139074339847 Q37934059-7122B1A0-E5D5-4E88-9448-D2F8928E06F0 Q38160822-F74CC77C-2AA4-4EE2-BD02-1639FAD978FF Q38696278-CB8A1D16-B5F3-43A0-8E3C-813D30A34B19 Q42148107-2FBE44DA-7DAC-403F-8175-DD15CAA7E02C Q42733799-10629FA3-EB13-4E99-B807-4CC9D4118339 Q43009143-5E9DD441-227C-48D7-8DA4-9D9AFF25CD62 Q46824108-06118E7D-0625-4983-8CB8-E2C1D76B41E4 Q47938743-EF365470-E779-4D6F-BB93-D8439712FF6D Q48055404-448F474D-C405-4025-B12F-5F909DDBA3FB Q48057664-4A4B2F51-680C-413E-8118-2E3A236DE64B Q48158911-4DAB1351-01F9-4C11-9A64-C2E221E48F52 Q51028141-F03700B8-D999-4C18-ADD9-A9439BC88A1E Q52628626-CA16FFF7-978F-4639-9F1D-A904CF23484E Q53480322-F43E12AF-76BB-4613-BFFC-0D641952981B

P2860

X-ray crystal structures of the estrogen-related receptor-gamma ligand binding domain in three functional states reveal the molecular basis of small molecule regulation

http://www.wikidata.org/entity/Q28264769

description

2006 nî lūn-bûn

@nan

2006 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2006 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

2006年の論文

@ja

2006年論文

@yue

2006年論文

@zh-hant

2006年論文

@zh-hk

2006年論文

@zh-mo

2006年論文

@zh-tw

2006年论文

@wuu

name

X-ray crystal structures of th ...... s of small molecule regulation

@ast

X-ray crystal structures of th ...... s of small molecule regulation

@en

X-ray crystal structures of th ...... s of small molecule regulation

@nl

type

label

X-ray crystal structures of th ...... s of small molecule regulation

@ast

X-ray crystal structures of th ...... s of small molecule regulation

@en

X-ray crystal structures of th ...... s of small molecule regulation

@nl

prefLabel

X-ray crystal structures of th ...... s of small molecule regulation

@ast

X-ray crystal structures of th ...... s of small molecule regulation

@en

X-ray crystal structures of th ...... s of small molecule regulation

@nl

P1433

Q28264769-395CB38C-B211-4231-A5B9-52E2F56B9015

P1476

Q28264769-B0C24D4D-B4FE-44F4-AAFA-B354253AA3BE

P2093

Q28264769-0229DEB0-6F15-4959-9D77-56739A372104

Q28264769-0959DF8A-D63A-458D-9127-17D6A90D6087

Q28264769-4B8A7607-9806-4AC2-9AEF-671BEE48A50B

Q28264769-5EFE624C-A2EE-49E6-8DD5-567FA051B96D

Q28264769-9510A540-9BE1-4BAB-A5FE-FA137EB8F0BD

Q28264769-A8F44C0C-E0E8-4F82-A696-225B2CFD59E5

Q28264769-B3D5390E-F709-49B2-A736-78FE1C7A2302

Q28264769-CD080666-589C-4CF2-AF49-24C9C161225F

Q28264769-F1E8726D-1874-4591-815A-CFC17B92961A

P2860

Q28264769-0087E483-3FD2-4DE9-AE43-1977293F60B3

Q28264769-03A706BB-C6C5-4CF1-9FBE-1ECD46EE22F2

Q28264769-3F1E273E-DD68-4D34-B7E8-E57E45BD00B0

Q28264769-48CE4F89-6815-4FB6-BED2-27415BF57AC7

Q28264769-6977DB5E-A211-4E8D-A812-D102BC21FE80

Q28264769-7C32D896-3979-41AD-909E-4BE46AD12079

Q28264769-7C8FD26B-927C-44DF-9EBB-0C2A8F19AC2C

Q28264769-7F9CC492-4D36-41A4-AAEA-146EEE30968A

Q28264769-8122C8A9-AA0E-42E4-BD30-547465B8397E

Q28264769-81FDCAF9-99C0-48A0-A194-53F715B2A7FD

P304

Q28264769-ED628545-5B33-4EA3-8184-F8D2846C303B

P31

Q28264769-9228BC47-42B9-40E3-8030-624BE27F0443

P3181

Q28264769-255A435D-A6C2-43AD-8534-4BF779032F60

P356

Q28264769-6A332A6F-91CB-4087-A52E-83591D7D3933

P407

Q28264769-A933AD37-FF1D-4AF4-A264-832664D8B355

P433

Q28264769-FB55A005-204A-4935-A573-A795A475B1D4

P478

Q28264769-92EFAFE5-5194-4BB9-8E9D-8E6BFFE91581

P577

Q28264769-D8B400F4-E202-44D7-9981-0270FD94A667

P698

Q28264769-6D969513-372F-4893-998F-7F7AF4420C02

P921

Q28264769-1053D425-C37F-4723-B621-392EF7CD0D22

Q28264769-901073FF-216C-4924-AF31-F78EF5437286

Q28264769-EA0D5082-B963-4114-BDF7-1F51A4811AB7

P3181

P356

P1433

Journal of Biological Chemistry

P1476

X-ray crystal structures of th ...... s of small molecule regulation

@en

P2093

Aaron B Miller

http://www.w3.org/2001/XMLSchema#string

David D McKee

http://www.w3.org/2001/XMLSchema#string

Liping Wang

http://www.w3.org/2001/XMLSchema#string

Lisa A Orband-Miller

http://www.w3.org/2001/XMLSchema#string

Millard H Lambert

http://www.w3.org/2001/XMLSchema#string

Robert T Nolte

http://www.w3.org/2001/XMLSchema#string

Thomas G Consler

http://www.w3.org/2001/XMLSchema#string

Timothy M Willson

http://www.w3.org/2001/XMLSchema#string

William J Zuercher

http://www.w3.org/2001/XMLSchema#string

P2860

Hormone-independent transcriptional activation and coactivator binding by novel orphan nuclear receptor ERR3

Improved methods for building protein models in electron density maps and the location of errors in these models

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

Processing of X-ray diffraction data collected in oscillation mode

The human nuclear xenobiotic receptor PXR: structural determinants of directed promiscuity

Structural basis for antagonist-mediated recruitment of nuclear co-repressors by PPARalpha

Structural and functional evidence for ligand-independent transcriptional activation by the estrogen-related receptor 3

The three-dimensional structure of the liver X receptor beta reveals a flexible ligand-binding pocket that can accommodate fundamentally different ligands

Molecular basis of agonism and antagonism in the oestrogen receptor

The structural basis of estrogen receptor/coactivator recognition and the antagonism of this interaction by tamoxifen

P304

37773-81

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P3181

1312597

http://www.w3.org/2001/XMLSchema#string

P356

10.1074/JBC.M608410200

http://www.w3.org/2001/XMLSchema#string

P407

P433

49

http://www.w3.org/2001/XMLSchema#string

P478

281

http://www.w3.org/2001/XMLSchema#string

P577

2006-12-08T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

16990259

http://www.w3.org/2001/XMLSchema#string

P921

X-ray crystallography

crystal structure