Regulation of immune cells by local-tissue oxygen tension: HIF1 alpha and adenosine receptors - Wikidata - wikimedia - TriplyDB

Regulation of immune cells by local-tissue oxygen tension: HIF1 alpha and adenosine receptors

Regulation of immune cells by local-tissue oxygen tension: HIF1 alpha and adenosine receptors

http://www.wikidata.org/entity/Q28268052

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miR-17-92 expression in differentiated T cells - implications for cancer immunotherapy Adenosine and hypoxia-inducible factor signaling in intestinal injury and recovery MicroRNAs in immune regulation--opportunities for cancer immunotherapy Treating lung inflammation with agonists of the adenosine A2A receptor: promises, problems and potential solutions Aggressiveness Niche: Can It Be the Foster Ground for Cancer Metastasis Precursors?Redox regulation of T-cell function: from molecular mechanisms to significance in human health and disease Hypoxic signaling during tissue repair and regenerative medicine Obstructive sleep apnea and cognitive impairment: addressing the blood-brain barrier Metabolic regulation of regulatory T cell development and function Temperature matters! And why it should matter to tumor immunologists HIF1A reduces acute lung injury by optimizing carbohydrate metabolism in the alveolar epithelium Detection of intra-tumor self antigen recognition during melanoma tumor progression in mice using advanced multimode confocal/two photon microscope Hypoxia: an alarm signal during intestinal inflammation The ever-expanding role of HIF in tumour and stromal biology Beneficial and detrimental role of adenosine signaling in diseases and therapy Hypoxia-inducible factors in the kidney The reno-vascular A2B adenosine receptor protects the kidney from ischemia A kinetic platform to determine the fate of nitric oxide in Escherichia coli Low dose rapamycin exacerbates autoimmune experimental uveitis Targeted deletion of HIF-1alpha gene in T cells prevents their inhibition in hypoxic inflamed tissues and improves septic mice survival.ATP release from vascular endothelia occurs across Cx43 hemichannels and is attenuated during hypoxia.Oxygen-independent stabilization of hypoxia inducible factor (HIF)-1 during RSV infection.Selective deletion of the A1 adenosine receptor abolishes heart-rate slowing effects of intravascular adenosine in vivo.Adenosine: an old drug newly discovered.T-cell activation under hypoxic conditions enhances IFN-gamma secretion.Inflammation-associated repression of vasodilator-stimulated phosphoprotein (VASP) reduces alveolar-capillary barrier function during acute lung injury.Peripheral blood mononuclear cells as a laboratory to study dementia in the elderly.Metabolic shifts in immunity and inflammation.Targeting the A2B adenosine receptor during gastrointestinal ischemia and inflammation Partial netrin-1 deficiency aggravates acute kidney injury Purinergic signaling during inflammation.Hypoxia inducible factor 1 alpha regulates T cell receptor signal transduction.Increased hypoxia-inducible factor 1α expression in lung cells of horses with recurrent airway obstruction.The resurgence of A2B adenosine receptor signaling Insight into the role of mTOR and metabolism in T cells reveals new potential approaches to preventing graft rejection.Gene expression profile of peripheral blood lymphocytes from renal cell carcinoma patients treated with IL-2, interferon-α and dendritic cell vaccine.A Parzen window-based approach for the detection of locally enriched transcription factor binding sites.Targeting hypoxia signalling for the treatment of ischaemic and inflammatory diseases Adenosine A2A receptors play an active role in mouse bone marrow-derived mesenchymal stem cell development.A2B adenosine receptor signaling attenuates acute lung injury by enhancing alveolar fluid clearance in mice

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Regulation of immune cells by local-tissue oxygen tension: HIF1 alpha and adenosine receptors

http://www.wikidata.org/entity/Q28268052

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2005 nî lūn-bûn

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2005 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

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Nature Reviews Immunology

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Regulation of immune cells by ...... alpha and adenosine receptors

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Dmitriy Lukashev

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Michail Sitkovsky

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P2860

The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis

C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation

OS-9 interacts with hypoxia-inducible factor 1alpha and prolyl hydroxylases to promote oxygen-dependent degradation of HIF-1alpha

Intracellular localisation of human HIF-1 alpha hydroxylases: implications for oxygen sensing

FIH-1 is an asparaginyl hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factor

HIF prolyl-hydroxylase 2 is the key oxygen sensor setting low steady-state levels of HIF-1alpha in normoxia

Oxygenation inhibits the physiological tissue-protecting mechanism and thereby exacerbates acute inflammatory lung injury.

Crucial role for ecto-5'-nucleotidase (CD73) in vascular leakage during hypoxia.

Targeting HIF-1 for cancer therapy

Regulation of mammalian O2 homeostasis by hypoxia-inducible factor 1

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10.1038/NRI1685

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16110315

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