The Wilms' tumor gene product WT1 activates or suppresses transcription through separate functional domains
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BASP1 is a transcriptional cosuppressor for the Wilms' tumor suppressor protein WT1WT1 suppresses synthesis of the epidermal growth factor receptor and induces apoptosisHigh affinity binding sites for the Wilms' tumour suppressor protein WT1WT1 interacts with the splicing factor U2AF65 in an isoform-dependent manner and can be incorporated into spliceosomesDenys-Drash syndrome associated WT1 glutamine 369 mutants have altered sequence-preferences and altered responses to epigenetic modificationsPar4 is a coactivator for a splice isoform-specific transcriptional activation domain in WT1In silico regulatory analysis for exploring human disease progression.Truncated WT1 mutants alter the subnuclear localization of the wild-type protein.A TCR-mimic antibody to WT1 bypasses tyrosine kinase inhibitor resistance in human BCR-ABL+ leukemiasThe Wilms' tumor suppressor WT1 induces estrogen-independent growth and anti-estrogen insensitivity in ER-positive breast cancer MCF7 cells.The Wilms' tumor suppressor gene (wt1) product regulates Dax-1 gene expression during gonadal differentiation.Identification of constitutional WT1 mutations, in patients with isolated diffuse mesangial sclerosis, and analysis of genotype/phenotype correlations by use of a computerized mutation databaseRegulation of ornithine decarboxylase gene expression by the Wilms' tumor suppressor WT1.Software and database for the analysis of mutations in the human WT1 geneImplication of Wt1 in the pathogenesis of nephrogenic failure in a mouse model of retinoic acid-induced caudal regression syndromeWT1 and PAX-2 podocyte expression in Denys-Drash syndrome and isolated diffuse mesangial sclerosis.A rodent model for Wilms tumors: embryonal kidney neoplasms induced by N-nitroso-N'-methylurea.The Wilms' tumor suppressor WT1 regulates expression of members of the epidermal growth factor receptor (EGFR) and estrogen receptor in acquired tamoxifen resistance.Correlation of germ-line mutations and two-hit inactivation of the WT1 gene with Wilms tumors of stromal-predominant histologyRole for Egr1 in the Transcriptional Program Associated with Neuronal Differentiation of PC12 Cells.Leydig cell loss and spermatogenic arrest in platelet-derived growth factor (PDGF)-A-deficient mice.Testicular development involves the spatiotemporal control of PDGFs and PDGF receptors gene expression and action.A second transcriptionally active DNA-binding site for the Wilms tumor gene product, WT1Expression and function of the leucine zipper protein Par-4 in apoptosis.Mapping and mutagenesis of the amino-terminal transcriptional repression domain of the Drosophila Krüppel protein.Ubiquitin specific protease 18 (Usp18) is a WT1 transcriptional targetInheritance of susceptibility to induction of nephroblastomas in the Noble rat.RNA binding by the Wilms tumor suppressor zinc finger proteins.Sequence and structural requirements for high-affinity DNA binding by the WT1 gene product.Platelet-derived growth factor A-chain gene transcription is mediated by positive and negative regulatory regions in the promoter.The transcriptional activation and repression domains of RFX1, a context-dependent regulator, can mutually neutralize their activities.Transactivation activity of Meq, a Marek's disease herpesvirus bZIP protein persistently expressed in latently infected transformed T cells.Functional domains in the Mig1 repressor.Mechanisms of leukemia resistance to antibody dependent cellular cytotoxicity.Opposite regulation of estrogen receptor-α and its variant ER-α36 by the Wilms' tumor suppressor WT1.Wilms' tumour-suppressor protein isoforms have opposite effects on Igf2 expression in primary embryonic cells, independently of p53 genotypeRole for first zinc finger of WT1 in DNA sequence specificity: Denys-Drash syndrome-associated WT1 mutant in ZF1 enhances affinity for a subset of WT1 binding sites.
P2860
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P2860
The Wilms' tumor gene product WT1 activates or suppresses transcription through separate functional domains
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1993 nî lūn-bûn
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1993 թուականի Մայիսին հրատարակուած գիտական յօդուած
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1993 թվականի մայիսին հրատարակված գիտական հոդված
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1993年の論文
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1993年論文
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1993年論文
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1993年論文
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1993年論文
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1993年論文
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1993年论文
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name
The Wilms' tumor gene product ...... gh separate functional domains
@ast
The Wilms' tumor gene product ...... gh separate functional domains
@en
The Wilms' tumor gene product ...... gh separate functional domains
@nl
type
label
The Wilms' tumor gene product ...... gh separate functional domains
@ast
The Wilms' tumor gene product ...... gh separate functional domains
@en
The Wilms' tumor gene product ...... gh separate functional domains
@nl
prefLabel
The Wilms' tumor gene product ...... gh separate functional domains
@ast
The Wilms' tumor gene product ...... gh separate functional domains
@en
The Wilms' tumor gene product ...... gh separate functional domains
@nl
P2093
P3181
P1476
The Wilms' tumor gene product ...... gh separate functional domains
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P2093
P304
P3181
P407
P577
1993-05-05T00:00:00Z