SUZ12 is required for both the histone methyltransferase activity and the silencing function of the EED-EZH2 complex
about
Molecular architecture of human polycomb repressive complex 2Cdx4 and menin co-regulate Hoxa9 expression in hematopoietic cellsFunctional characterization of EZH2β reveals the increased complexity of EZH2 isoforms involved in the regulation of mammalian gene expressionAebp2 as an epigenetic regulator for neural crest cells.Composition and histone substrates of polycomb repressive group complexes change during cellular differentiationMethyl-H3K9-binding protein MPP8 mediates E-cadherin gene silencing and promotes tumour cell motility and invasionCyclin-dependent kinases regulate epigenetic gene silencing through phosphorylation of EZH2Role of histone H2A ubiquitination in Polycomb silencingAn H3K36 methylation-engaging Tudor motif of polycomb-like proteins mediates PRC2 complex targetingThe polycomb group protein EZH2 is required for mammalian circadian clock functionTrim24 targets endogenous p53 for degradationmiR-101 is down-regulated in glioblastoma resulting in EZH2-induced proliferation, migration, and angiogenesisEZH2 methyltransferase and H3K27 methylation in breast cancerIn vitro and in vivo analyses of a Phe/Tyr switch controlling product specificity of histone lysine methyltransferasesEZH1 mediates methylation on histone H3 lysine 27 and complements EZH2 in maintaining stem cell identity and executing pluripotencyPolycomb Repressive Complex 2 and Trithorax modulate Drosophila longevity and stress resistanceMicroRNA-126 regulates HOXA9 by binding to the homeoboxRole of hPHF1 in H3K27 methylation and Hox gene silencingMammalian ASH1L is a histone methyltransferase that occupies the transcribed region of active genesTargeting histone methylation for cancer therapy: enzymes, inhibitors, biological activity and perspectivesTargeting histone methyltransferases and demethylases in clinical trials for cancer therapyThe interplay of histone modifications - writers that readThe quest for mammalian Polycomb response elements: are we there yet?Polycomb Group (PcG) Proteins and Human Cancers: Multifaceted Functions and Therapeutic ImplicationsChemical probes of histone lysine methyltransferasesChromatin targeting drugs in cancer and immunityPolycomb repressive complex 2 structure with inhibitor reveals a mechanism of activation and drug resistance.Snail2/Slug cooperates with Polycomb repressive complex 2 (PRC2) to regulate neural crest development.Binding of different histone marks differentially regulates the activity and specificity of polycomb repressive complex 2 (PRC2)Crystal Structure and Functional Analysis of JMJD5 Indicate an Alternate Specificity and FunctionStructure of the Catalytic Domain of EZH2 Reveals Conformational Plasticity in Cofactor and Substrate Binding Sites and Explains Oncogenic MutationsStructural Context of Disease-Associated Mutations and Putative Mechanism of Autoinhibition Revealed by X-Ray Crystallographic Analysis of the EZH2-SET DomainCell-based assays to support the profiling of small molecules with histone methyltransferase and demethylase modulatory activityJAZF1/SUZ12 gene fusion in endometrial stromal sarcomasEpigenetic treatment of pancreatic cancer: is there a therapeutic perspective on the horizon?Diverse involvement of EZH2 in cancer epigeneticsControl of developmental regulators by Polycomb in human embryonic stem cellsA novel mutation in EED associated with overgrowthSWI/SNF-mutant cancers depend on catalytic and non-catalytic activity of EZH2Coordinated regulation of transcriptional repression by the RBP2 H3K4 demethylase and Polycomb-Repressive Complex 2
P2860
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P2860
SUZ12 is required for both the histone methyltransferase activity and the silencing function of the EED-EZH2 complex
description
2004 nî lūn-bûn
@nan
2004 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
SUZ12 is required for both the ...... nction of the EED-EZH2 complex
@ast
SUZ12 is required for both the ...... nction of the EED-EZH2 complex
@en
SUZ12 is required for both the ...... nction of the EED-EZH2 complex
@nl
type
label
SUZ12 is required for both the ...... nction of the EED-EZH2 complex
@ast
SUZ12 is required for both the ...... nction of the EED-EZH2 complex
@en
SUZ12 is required for both the ...... nction of the EED-EZH2 complex
@nl
prefLabel
SUZ12 is required for both the ...... nction of the EED-EZH2 complex
@ast
SUZ12 is required for both the ...... nction of the EED-EZH2 complex
@en
SUZ12 is required for both the ...... nction of the EED-EZH2 complex
@nl
P3181
P1433
P1476
SUZ12 is required for both the ...... nction of the EED-EZH2 complex
@en
P2093
P3181
P356
10.1016/J.MOLCEL.2004.06.020
P407
P50
P577
2004-07-01T00:00:00Z