Complexes of Ras.GTP with Raf-1 and mitogen-activated protein kinase kinase
about
Human JIK, a novel member of the STE20 kinase family that inhibits JNK and is negatively regulated by epidermal growth factorSecond nature: biological functions of the Raf-1 "kinase"Activated Ras interacts with the Ral guanine nucleotide dissociation stimulatorExpression of Q227L-galphas in MCF-7 human breast cancer cells inhibits tumorigenesisRaf family kinases: old dogs have learned new tricksRegulation of Raf-1 kinase activity by the 14-3-3 family of proteinsCo-activation of RanGTPase and inhibition of GTP dissociation by Ran-GTP binding protein RanBP114-3-3 is not essential for Raf-1 function: identification of Raf-1 proteins that are biologically activated in a 14-3-3- and Ras-independent mannerIdentification of a novel guanine nucleotide exchange factor for the Rho GTPaseMitogen-activated protein kinase activation requires two signal inputs from the human anaphylatoxin C5a receptorActivation of the c-Jun N-terminal kinase pathway by a novel protein kinase related to human germinal center kinaseEvidence for in vivo phosphorylation of the Grb2 SH2-domain binding site on focal adhesion kinase by Src-family protein-tyrosine kinasesCloning and characterization of p97MAPK, a novel human homolog of rat ERK-3The RafC1 cysteine-rich domain contains multiple distinct regulatory epitopes which control Ras-dependent Raf activationMeaningful relationships: the regulation of the Ras/Raf/MEK/ERK pathway by protein interactionsInsulin regulates the dynamic balance between Ras and Rap1 signaling by coordinating the assembly states of the Grb2-SOS and CrkII-C3G complexes.Ras binding opens c-Raf to expose the docking site for mitogen-activated protein kinase kinase.Mechanism of suppression of the Raf/MEK/extracellular signal-regulated kinase pathway by the raf kinase inhibitor proteinActivation of phosphoinositide 3-kinase by interaction with Ras and by point mutationInhibition of phosphatidylinositol 3-kinase activity by association with 14-3-3 proteins in T cellsIdentification of the guanine nucleotide dissociation stimulator for Ral as a putative effector molecule of R-ras, H-ras, K-ras, and RapActivation of ternary complex factor Elk-1 by MAP kinasesProtein kinase A antagonizes platelet-derived growth factor-induced signaling by mitogen-activated protein kinase in human arterial smooth muscle cellsRAS and RAF-1 form a signalling complex with MEK-1 but not MEK-2.Shc, Grb2, Sos1, and a 150-kilodalton tyrosine-phosphorylated protein form complexes with Fms in hematopoietic cellsRetroviral oncogenes: a historical primerInteraction of activated Ras with Raf-1 alone may be sufficient for transformation of rat2 cellsRheb interacts with Raf-1 kinase and may function to integrate growth factor- and protein kinase A-dependent signals.A proline-rich sequence unique to MEK1 and MEK2 is required for raf binding and regulates MEK functionA human protein selected for interference with Ras function interacts directly with Ras and competes with Raf1A comprehensive pathway map of epidermal growth factor receptor signalingRab3 reversibly recruits rabphilin to synaptic vesicles by a mechanism analogous to raf recruitment by rasMicroRNAs mediated regulation of MAPK signaling pathways in chronic myeloid leukemiaObesity and cancer, a case for insulin signalingMolecular characterizations of glioblastoma, targeted therapy, and clinical results to dateDeregulated signaling pathways in glioblastoma multiforme: molecular mechanisms and therapeutic targetsRegulation of ROCK activity in cancerTargeting RAF kinases for cancer therapy: BRAF-mutated melanoma and beyondActivated Ras as a Therapeutic Target: Constraints on Directly Targeting Ras Isoforms and Wild-Type versus Mutated ProteinsSolution structure of the Ras-binding domain of RGL
P2860
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P2860
Complexes of Ras.GTP with Raf-1 and mitogen-activated protein kinase kinase
description
1993 nî lūn-bûn
@nan
1993 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1993 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
name
Complexes of Ras.GTP with Raf-1 and mitogen-activated protein kinase kinase
@ast
Complexes of Ras.GTP with Raf-1 and mitogen-activated protein kinase kinase
@en
Complexes of Ras.GTP with Raf-1 and mitogen-activated protein kinase kinase
@nl
type
label
Complexes of Ras.GTP with Raf-1 and mitogen-activated protein kinase kinase
@ast
Complexes of Ras.GTP with Raf-1 and mitogen-activated protein kinase kinase
@en
Complexes of Ras.GTP with Raf-1 and mitogen-activated protein kinase kinase
@nl
prefLabel
Complexes of Ras.GTP with Raf-1 and mitogen-activated protein kinase kinase
@ast
Complexes of Ras.GTP with Raf-1 and mitogen-activated protein kinase kinase
@en
Complexes of Ras.GTP with Raf-1 and mitogen-activated protein kinase kinase
@nl
P2093
P3181
P356
P1433
P1476
Complexes of Ras.GTP with Raf-1 and mitogen-activated protein kinase kinase
@en
P2093
B M Willumsen
S A Moodie
P304
P3181
P356
10.1126/SCIENCE.8503013
P407
P577
1993-06-11T00:00:00Z