Lyn physically associates with the erythropoietin receptor and may play a role in activation of the Stat5 pathway
about
The distal region and receptor tyrosines of the Epo receptor are non-essential for in vivo erythropoiesisOrigins of the Vertebrate Erythro/Megakaryocytic SystemJAK2 activation by growth hormone and other cytokinesMelanocortins contribute to sequential differentiation and enucleation of human erythroblasts via melanocortin receptors 1, 2 and 5Src transduces erythropoietin-induced differentiation signals through phosphatidylinositol 3-kinase.The Src family kinase Hck couples BCR/ABL to STAT5 activation in myeloid leukemia cells.Erythropoietin down-regulates stem cell factor receptor (Kit) expression in the leukemic proerythroblast: role of Lyn kinaseErythroid cells rendered erythropoietin independent by infection with Friend spleen focus-forming virus show constitutive activation of phosphatidylinositol 3-kinase and Akt kinase: involvement of insulin receptor substrate-related adapter proteins.Advances in understanding the pathogenesis of primary familial and congenital polycythaemiaThe interaction of LCK and the CD4 co-receptor alters the dose response of T-cells to interleukin-7.DNA damage stress and inhibition of Jak2-V617F cause its degradation and synergistically induce apoptosis through activation of GSK3βEvaluation of functional erythropoietin receptor status in skeletal muscle in vivo: acute and prolonged studies in healthy human subjectsErythropoietin receptor signaling is membrane raft dependent.Direct activation of STAT5 by ETV6-LYN fusion protein promotes induction of myeloproliferative neoplasm with myelofibrosis.Lyn kinase promotes erythroblast expansion and late-stage development.Src family kinases are important negative regulators of G-CSF-dependent granulopoiesisLyn Delivers Bacteria to Lysosomes for Eradication through TLR2-Initiated Autophagy Related PhagocytosisFunctions of the Lyn tyrosine kinase in health and diseaseA KIT juxtamembrane PY567 -directed pathway provides nonredundant signals for erythroid progenitor cell development and stress erythropoiesis.Proliferation and survival signaling from both Jak2-V617F and Lyn involving GSK3 and mTOR/p70S6K/4EBP1 in PVTL-1 cell line newly established from acute myeloid leukemia transformed from polycythemia vera.Evidence That Erythropoietin Modulates Neuroinflammation through Differential Action on Neurons, Astrocytes, and Microglia.Deficiency of Src family kinases compromises the repopulating ability of hematopoietic stem cellsPECAM-1 is involved in BCR/ABL signaling and may downregulate imatinib-induced apoptosis of Philadelphia chromosome-positive leukemia cells.Core erythropoietin receptor signals for late erythroblast development.Lyn mediates FIP1L1-PDGFRA signal pathway facilitating IL-5RA intracellular signal through FIP1L1-PDGFRA/JAK2/Lyn/Akt network complex in CEL.The Growth Hormone Receptor: Mechanism of Receptor Activation, Cell Signaling, and Physiological Aspects.EPO binds EPOR:JAK2:LYN:IRS2
P2860
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P2860
Lyn physically associates with the erythropoietin receptor and may play a role in activation of the Stat5 pathway
description
1998 nî lūn-bûn
@nan
1998 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Lyn physically associates with ...... ctivation of the Stat5 pathway
@ast
Lyn physically associates with ...... ctivation of the Stat5 pathway
@en
Lyn physically associates with ...... ctivation of the Stat5 pathway
@nl
type
label
Lyn physically associates with ...... ctivation of the Stat5 pathway
@ast
Lyn physically associates with ...... ctivation of the Stat5 pathway
@en
Lyn physically associates with ...... ctivation of the Stat5 pathway
@nl
prefLabel
Lyn physically associates with ...... ctivation of the Stat5 pathway
@ast
Lyn physically associates with ...... ctivation of the Stat5 pathway
@en
Lyn physically associates with ...... ctivation of the Stat5 pathway
@nl
P2093
P1433
P1476
Lyn physically associates with ...... ctivation of the Stat5 pathway
@en
P2093
P304
P407
P577
1998-05-01T00:00:00Z