Core erythropoietin receptor signals for late erythroblast development.
about
Melanocortins contribute to sequential differentiation and enucleation of human erythroblasts via melanocortin receptors 1, 2 and 5Defining an EPOR- regulated transcriptome for primary progenitors, including Tnfr-sf13c as a novel mediator of EPO- dependent erythroblast formationFuture alternative therapies for β-thalassemia.Advances in understanding the pathogenesis of primary familial and congenital polycythaemiaMacrophages as novel target cells for erythropoietin.Stat5 regulates cellular iron uptake of erythroid cells via IRP-2 and TfR-1.Leukemogenic Ptpn11 allele causes defective erythropoiesis in mice.Emerging EPO and EPO receptor regulators and signal transducers.Contrasting dynamic responses in vivo of the Bcl-xL and Bim erythropoietic survival pathways.BMP4, SCF, and hypoxia cooperatively regulate the expansion of murine stress erythroid progenitors.Erythropoietin modulation of podocalyxin and a proposed erythroblast niche.Erythropoietin involves the phosphatidylinositol 3-kinase pathway, 14-3-3 protein and FOXO3a nuclear trafficking to preserve endothelial cell integrityMicroglial integrity is maintained by erythropoietin through integration of Akt and its substrates of glycogen synthase kinase-3beta, beta-catenin, and nuclear factor-kappaB.EPO modulation of cell-cycle regulatory genes, and cell division, in primary bone marrow erythroblastsSpry1 as a novel regulator of erythropoiesis, EPO/EPOR target, and suppressor of JAK2.The SH2B1 adaptor protein associates with a proximal region of the erythropoietin receptor.EPO receptor circuits for primary erythroblast survivalErythropoietin: elucidating new cellular targets that broaden therapeutic strategiesAttenuation of EPO-dependent erythroblast formation by death-associated protein kinase-2.The Src homology 2 domain tyrosine phosphatases SHP-1 and SHP-2: diversified control of cell growth, inflammation, and injury.Erythropoietin and oxidative stress.Erythropoietin-induced phosphorylation/degradation of BIM contributes to survival of erythroid cells.CNTO 530 functions as a potent EPO mimetic via unique sustained effects on bone marrow proerythroblast pools.Polycythemia vera erythroid precursors exhibit increased proliferation and apoptosis resistance associated with abnormal RAS and PI3K pathway activation.Erythropoietic stimulating agents.Erythropoietin receptor response circuitsPeginesatide and erythropoietin stimulate similar erythropoietin receptor-mediated signal transduction and gene induction events.Anemia, ineffective erythropoiesis, and hepcidin: interacting factors in abnormal iron metabolism leading to iron overload in β-thalassemia.JAK2 inhibitors in the treatment of myeloproliferative neoplasms.Signal, transduction, and the hematopoietic stem cell.DYRK3 dual-specificity kinase attenuates erythropoiesis during anemiaJAK2/Y343/STAT5 signaling axis is required for erythropoietin-mediated protection against ischemic injury in primary renal tubular epithelial cellsGenome-wide identification of TAL1's functional targets: insights into its mechanisms of action in primary erythroid cells.Reno-endocrinal disorders: A basic understanding of the molecular geneticsGoverning roles for Trib3 pseudokinase during stress erythropoiesis.Iron modulation of erythropoiesis is associated with Scribble-mediated control of the erythropoietin receptor.Biochemical measurements on single erythroid progenitor cells shed light on the combinatorial regulation of red blood cell production.
P2860
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P2860
Core erythropoietin receptor signals for late erythroblast development.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
Core erythropoietin receptor signals for late erythroblast development.
@en
type
label
Core erythropoietin receptor signals for late erythroblast development.
@en
prefLabel
Core erythropoietin receptor signals for late erythroblast development.
@en
P2093
P2860
P1433
P1476
Core erythropoietin receptor signals for late erythroblast development.
@en
P2093
Don M Wojchowski
Madhu P Menon
P2860
P304
P356
10.1182/BLOOD-2005-02-0684
P407
P577
2005-12-06T00:00:00Z