Alternative reading frames of the INK4a tumor suppressor gene encode two unrelated proteins capable of inducing cell cycle arrest
about
Multiple novel nesprin-1 and nesprin-2 variants act as versatile tissue-specific intracellular scaffoldsMain roads to melanomaPremature senescence involving p53 and p16 is activated in response to constitutive MEK/MAPK mitogenic signalingThe human tumor suppressor arf interacts with spinophilin/neurabin II, a type 1 protein-phosphatase-binding proteinAdenovirus-mediated overexpression of p14(ARF) induces p53 and Bax-independent apoptosisCARF is a novel protein that cooperates with mouse p19ARF (human p14ARF) in activating p53mrtl-A translation/localization regulatory protein encoded within the human c-myc locus and distributed throughout the endoplasmic and nucleoplasmic reticular networkA novel nuclear interactor of ARF and MDM2 (NIAM) that maintains chromosomal stabilityMAPKAP kinase MK2 maintains self-renewal capacity of haematopoietic stem cellsTumor suppressor ARF promotes non-classic proteasome-independent polyubiquitination of COMMD1p14ARF induces G2 cell cycle arrest in p53- and p21-deficient cells by down-regulating p34cdc2 kinase activityA novel ARF-binding protein (LZAP) alters ARF regulation of HDM2Increased levels of the FoxM1 transcription factor accelerate development and progression of prostate carcinomas in both TRAMP and LADY transgenic miceGerm line transmission of the Cdk4(R24C) mutation facilitates tumorigenesis and escape from cellular senescence.The leptin receptor promoter controls expression of a second distinct proteinTargeting of C-terminal binding protein (CtBP) by ARF results in p53-independent apoptosis.CDC25A phosphatase is a target of E2F and is required for efficient E2F-induced S phaseN-terminal polyubiquitination and degradation of the Arf tumor suppressorp19ARF determines the balance between normal cell proliferation rate and apoptosis during mammary gland developmentTwist is a potential oncogene that inhibits apoptosisp53-independent functions of the p19(ARF) tumor suppressorEpigenetic regulation of the INK4b-ARF-INK4a locus: in sickness and in healthBmi1, stem cells, and senescence regulationTumor suppressors: enhancers or suppressors of regeneration?Foxm1b transcription factor is essential for development of hepatocellular carcinomas and is negatively regulated by the p19ARF tumor suppressorPhysical and functional interactions of the Arf tumor suppressor protein with nucleophosmin/B23Cellular senescence and tumor suppressor gene p16P19(ARF) stabilizes p53 by blocking nucleo-cytoplasmic shuttling of Mdm2Epstein-Barr virus and Burkitt lymphomaRapid asymmetric evolution of a dual-coding tumor suppressor INK4a/ARF locus contradicts its functionp19Arf suppresses growth, progression, and metastasis of Hras-driven carcinomas through p53-dependent and -independent pathwaysp14ARF expression in invasive breast cancers and ductal carcinoma in situ--relationships to p53 and Hdm2Towards a Better Understanding of the Molecular Mechanisms Involved in Sunlight-Induced MelanomaOscillating evolution of a mammalian locus with overlapping reading frames: an XLalphas/ALEX relay.Implications of Genetic and Epigenetic Alterations of CDKN2A (p16(INK4a)) in CancerOsteosarcoma Genetics and Epigenetics: Emerging Biology and Candidate TherapiesHuman papillomavirus induced transformation in cervical and head and neck cancersAn N-terminal p14ARF peptide blocks Mdm2-dependent ubiquitination in vitro and can activate p53 in vivoThe INK4 family of cell cycle inhibitors in cancerPex19p dampens the p19ARF-p53-p21WAF1 tumor suppressor pathway
P2860
Q21134152-A95FE998-267D-436C-A75F-BB75B13F3235Q21245465-5F0292D8-A465-4DBB-8C77-17E278DE0FBDQ22003910-48D657AE-3BA0-476F-B4A8-FAFEC4781886Q24291005-373E7AC9-00F8-42B0-B45A-BF6BDE9D0E14Q24300313-D40405DF-35F7-4F5F-B469-B461CACBBE96Q24303502-4FC40888-9B28-4A35-B308-FE27500E7C72Q24315822-EB3EB231-5B66-4D52-888C-0A25305F8427Q24316305-D85164C1-CEBC-4842-9C66-20DAB86CCB79Q24316376-3736C314-D7E5-4B75-B17B-9AD710CBB3E2Q24318304-FE59B7B2-EE15-4B77-83BF-9229BF7CFE64Q24319978-0FFFC538-77C4-4A89-A82B-E10A717DEAD8Q24328749-6CBE9218-E55A-4D66-BCD8-75C8D20CA2AEQ24537872-1991A781-8109-4A0F-953F-A39190783960Q24540051-D680F7CD-B0E7-4A07-8AF3-E8C71C91CF74Q24544887-C03273B1-E269-45A2-99EF-891A9611D70CQ24548025-F5302BB8-423A-4D8B-BC50-9697EDBC9454Q24554436-D9FA187E-0847-4EC2-A811-6A4C05024B91Q24561681-9AFA1174-0425-4ED3-8B94-BA13DED2EAF0Q24564901-05ECF1EC-C4DA-4AB0-823F-4F60C44E1658Q24599468-2604B195-ED98-4264-A729-4D947AB894FEQ24600863-8081DA47-B662-45CB-B332-60FB1B538FBBQ24604190-CF9E6845-948F-4139-A355-AF14D241B69FQ24614474-7139C8C1-DEE4-4DD2-B8B5-F8899361B332Q24618747-1667939E-3B26-43CC-B976-4F7CAC499382Q24624817-D1D9520C-B640-432C-82A6-B640ABD0E715Q24629309-F44882E1-954B-4A72-9CB6-BDEF9AE76559Q24629853-EBB9C57C-C343-46DF-80DB-C3977F3E991BQ24650492-525B52E4-0951-4522-9CB6-BE32359E06D7Q24669890-9AFC4415-FD30-44CD-84A3-EED233C05FAAQ24682671-8805CAEF-032E-4753-BC8B-032E7B9F9C15Q24799059-D25D44F1-BE05-422E-9FCA-AC7016E9E546Q24806368-B9D408CD-C51E-44AD-A0A7-FB5DE9084B46Q24806589-C223EFC6-43DD-43BE-982C-81329EEB8556Q24813391-CA73A022-BC63-4F6F-A8EA-7D9AEF2DD65FQ26739706-2555445F-E631-4D92-AB3E-11185B595FE4Q26782646-8497FAB3-1BF6-452F-BDAA-7E59EE0A0D39Q27003141-FE30F040-F6B5-448A-8387-5B36CA07FB5AQ28144965-D5903254-3EC4-46E0-88B0-5447159DF352Q28145080-7E3CBD6F-9131-41A7-B7D8-1DAF04DEA992Q28205682-0B42C7F3-2AC0-44B9-B593-99FA6FB6B575
P2860
Alternative reading frames of the INK4a tumor suppressor gene encode two unrelated proteins capable of inducing cell cycle arrest
description
1995 nî lūn-bûn
@nan
1995 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
Alternative reading frames of ...... of inducing cell cycle arrest
@ast
Alternative reading frames of ...... of inducing cell cycle arrest
@en
Alternative reading frames of ...... of inducing cell cycle arrest
@nl
type
label
Alternative reading frames of ...... of inducing cell cycle arrest
@ast
Alternative reading frames of ...... of inducing cell cycle arrest
@en
Alternative reading frames of ...... of inducing cell cycle arrest
@nl
prefLabel
Alternative reading frames of ...... of inducing cell cycle arrest
@ast
Alternative reading frames of ...... of inducing cell cycle arrest
@en
Alternative reading frames of ...... of inducing cell cycle arrest
@nl
P2093
P3181
P1433
P1476
Alternative reading frames of ...... of inducing cell cycle arrest
@en
P2093
P304
P3181
P356
10.1016/0092-8674(95)90214-7
P407
P577
1995-12-15T00:00:00Z