Selective regulation of acid-sensing ion channel 1 by serine proteases
about
Identification of the SPLUNC1 ENaC-inhibitory domain yields novel strategies to treat sodium hyperabsorption in cystic fibrosis airway epithelial culturesThe receptor site of the spider toxin PcTx1 on the proton-gated cation channel ASIC1aStructure and activity of the acid-sensing ion channelsThe epithelial sodium channel δ-subunit: new notes for an old songTwo aspects of ASIC function: Synaptic plasticity and neuronal injury.A combined computational and functional approach identifies new residues involved in pH-dependent gating of ASIC1a.A segment of gamma ENaC mediates elastase activation of Na+ transportAcid-Sensing Ion Channels and PainProteolytic cleavage of human acid-sensing ion channel 1 by the serine protease matriptaseDemonstration of proteolytic activation of the epithelial sodium channel (ENaC) by combining current measurements with detection of cleavage fragmentsAcid-sensitive ion channels and receptorsENaCs and ASICs as therapeutic targets.Identification of SPLUNC1's ENaC-inhibitory domain yields novel strategies to treat sodium hyperabsorption in cystic fibrosis airways.Protonation controls ASIC1a activity via coordinated movements in multiple domains.Protons and Ca2+: ionic allies in tumor progression?Modulation of acid-sensing ion channels: molecular mechanisms and therapeutic potential.Acid-sensing ion channels in pathological conditions.Translational strategies for neuroprotection in ischemic stroke--focusing on acid-sensing ion channel 1a.Proton-sensitive cation channels and ion exchangers in ischemic brain injury: new therapeutic targets for stroke?Regulating Factors in Acid-Sensing Ion Channel 1a Function.The function and regulation of acid-sensing ion channels (ASICs) and the epithelial Na(+) channel (ENaC): IUPHAR Review 19.Proteinases, Their Extracellular Targets, and Inflammatory Signaling.The role of ASICS in cerebral ischemia.Intersubunit interactions between mutant DEG/ENaCs induce synthetic neurotoxicity.σ-1 Receptor Inhibition of ASIC1a Channels is Dependent on a Pertussis Toxin-Sensitive G-Protein and an AKAP150/Calcineurin Complex.Trypsin cleaves acid-sensing ion channel 1a in a domain that is critical for channel gating.Acid-sensing ion channels contribute to chemosensitivity of breathing-related neurons of the nucleus of the solitary tract.Endogenous arginine-phenylalanine-amide-related peptides alter steady-state desensitization of ASIC1a.Proton sensitivity of ASIC1 appeared with the rise of fishes by changes of residues in the region that follows TM1 in the ectodomain of the channel
P2860
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P2860
Selective regulation of acid-sensing ion channel 1 by serine proteases
description
2004 nî lūn-bûn
@nan
2004 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Selective regulation of acid-sensing ion channel 1 by serine proteases
@ast
Selective regulation of acid-sensing ion channel 1 by serine proteases
@en
Selective regulation of acid-sensing ion channel 1 by serine proteases
@nl
type
label
Selective regulation of acid-sensing ion channel 1 by serine proteases
@ast
Selective regulation of acid-sensing ion channel 1 by serine proteases
@en
Selective regulation of acid-sensing ion channel 1 by serine proteases
@nl
prefLabel
Selective regulation of acid-sensing ion channel 1 by serine proteases
@ast
Selective regulation of acid-sensing ion channel 1 by serine proteases
@en
Selective regulation of acid-sensing ion channel 1 by serine proteases
@nl
P2093
P2860
P356
P1476
Selective regulation of acid-sensing ion channel 1 by serine proteases
@en
P2093
Anne Boesch
Marija Vukicevic
Olivier Poirot
Stephan Kellenberger
P2860
P304
P356
10.1074/JBC.M407381200
P407
P577
2004-09-10T00:00:00Z