Trypsin cleaves acid-sensing ion channel 1a in a domain that is critical for channel gating.
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Structure and activity of the acid-sensing ion channelsThe Concise Guide to PHARMACOLOGY 2013/14: ion channelsA combined computational and functional approach identifies new residues involved in pH-dependent gating of ASIC1a.A segment of gamma ENaC mediates elastase activation of Na+ transportAcid-Sensing Ion Channels and PainThe contact region between three domains of the extracellular loop of ASIC1a is critical for channel function.The interaction between the first transmembrane domain and the thumb of ASIC1a is critical for its N-glycosylation and trafficking.Proteolytic cleavage of human acid-sensing ion channel 1 by the serine protease matriptaseDemonstration of proteolytic activation of the epithelial sodium channel (ENaC) by combining current measurements with detection of cleavage fragmentsIdentification of a calcium permeable human acid-sensing ion channel 1 transcript variant.Functional architecture of olfactory ionotropic glutamate receptors.Atomic level characterization of the nonproton ligand-sensing domain of ASIC3 channels.Extracellular Subunit Interactions Control Transitions between Functional States of Acid-sensing Ion Channel 1a.ENaCs and ASICs as therapeutic targets.Protonation controls ASIC1a activity via coordinated movements in multiple domains.Modulation of acid-sensing ion channels: molecular mechanisms and therapeutic potential.Insight into DEG/ENaC channel gating from genetics and structure.Acid-sensing ion channels in pathological conditions.Translational strategies for neuroprotection in ischemic stroke--focusing on acid-sensing ion channel 1a.Proton-sensitive cation channels and ion exchangers in ischemic brain injury: new therapeutic targets for stroke?Regulating Factors in Acid-Sensing Ion Channel 1a Function.The function and regulation of acid-sensing ion channels (ASICs) and the epithelial Na(+) channel (ENaC): IUPHAR Review 19.Proteinases, Their Extracellular Targets, and Inflammatory Signaling.The role of ASICS in cerebral ischemia.Acid-sensing ion channels in rat hypothalamic vasopressin neurons of the supraoptic nucleus.Intersubunit interactions between mutant DEG/ENaCs induce synthetic neurotoxicity.Cell segmentation and pipette identification for automated patch clamp recording
P2860
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P2860
Trypsin cleaves acid-sensing ion channel 1a in a domain that is critical for channel gating.
description
2005 nî lūn-bûn
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2005年の論文
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2005年学术文章
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2005年学术文章
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2005年学术文章
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2005年学术文章
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name
Trypsin cleaves acid-sensing i ...... s critical for channel gating.
@en
Trypsin cleaves acid-sensing i ...... s critical for channel gating.
@nl
type
label
Trypsin cleaves acid-sensing i ...... s critical for channel gating.
@en
Trypsin cleaves acid-sensing i ...... s critical for channel gating.
@nl
prefLabel
Trypsin cleaves acid-sensing i ...... s critical for channel gating.
@en
Trypsin cleaves acid-sensing i ...... s critical for channel gating.
@nl
P2093
P2860
P356
P1476
Trypsin cleaves acid-sensing i ...... s critical for channel gating.
@en
P2093
Anne Boesch
Aurélien Boillat
Gilles Weder
Marija Vukicevic
P2860
P304
P356
10.1074/JBC.M510472200
P407
P577
2005-11-09T00:00:00Z