Regulation of p53 by the ubiquitin-conjugating enzymes UbcH5B/C in vivo
about
Turning the RING domain protein MdmX into an active ubiquitin-protein ligaseThe deubiquitinating enzyme USP2a regulates the p53 pathway by targeting Mdm2Suppression of the deubiquitinating enzyme USP5 causes the accumulation of unanchored polyubiquitin and the activation of p53Members of the E2D (UbcH5) family mediate the ubiquitination of the conserved cysteine of Pex5p, the peroxisomal import receptorA comprehensive framework of E2-RING E3 interactions of the human ubiquitin-proteasome systemUbc4/5 and c-Cbl continue to ubiquitinate EGF receptor after internalization to facilitate polyubiquitination and degradationTranscription factor TAFII250 promotes Mdm2-dependent turnover of p53E2-25K/Hip-2 regulates caspase-12 in ER stress-mediated Abeta neurotoxicityReconstitution of Mdm2-dependent post-translational modifications of p53 in yeast.The p53 orchestra: Mdm2 and Mdmx set the toneAutoactivation of the MDM2 E3 ligase by intramolecular interaction.MDM2, MDMX and p53 in oncogenesis and cancer therapyMechanism of p53 stabilization by ATM after DNA damage.Limiting the power of p53 through the ubiquitin proteasome pathway.SLUG-induced elevation of D1 cyclin in breast cancer cells through the inhibition of its ubiquitination.Proteomic identification and analysis of K63-linked ubiquitin conjugatesp53 directly transactivates Δ133p53α, regulating cell fate outcome in response to DNA damageInhibition of UBE2D3 expression attenuates radiosensitivity of MCF-7 human breast cancer cells by increasing hTERT expression and activity.Microarray characterization of gene expression changes in blood during acute ethanol exposureGene expression modifications in Wharton's Jelly mesenchymal stem cells promoted by prolonged in vitro culturingRegulation of p53 localization and activity by Ubc13.Identification and characterization of novel immunomodulatory bursal-derived pentapeptide-II (BPP-II)RNAi screen identifies UBE2D3 as a mediator of all-trans retinoic acid-induced cell growth arrest in human acute promyelocytic NB4 cells.Functional analysis and consequences of Mdm2 E3 ligase inhibition in human tumor cellsRegulation of ubiquitin-proteasome system mediated degradation by cytosolic stress.Regulation of the Abundance of Kaposi's Sarcoma-Associated Herpesvirus ORF50 Protein by Oncoprotein MDM2Accumulation of p53 via down-regulation of UBE2D family genes is a critical pathway for cadmium-induced renal toxicityDifferent Regulation of p53 Expression by Cadmium Exposure in Kidney, Liver, Intestine, Vasculature, and Brain AstrocytesAuto-ubiquitination of Mdm2 enhances its substrate ubiquitin ligase activity.Forty-eight hours of unloading and 24 h of reloading lead to changes in global gene expression patterns related to ubiquitination and oxidative stress in humans.Discovery, in vivo activity, and mechanism of action of a small-molecule p53 activator.Destabilization of Rb by human papillomavirus E7 is cell cycle dependent: E2-25K is involved in the proteolysis.Regulation of p53--insights into a complex process.Regulation of p53: a collaboration between Mdm2 and Mdmx.The exportomer: the peroxisomal receptor export machinery.Ubiquitination involved enzymes and cancer.Molecular Liver Cancer Prevention in Cirrhosis by Organ Transcriptome Analysis and Lysophosphatidic Acid Pathway Inhibition.The NEDD8 inhibitor MLN4924 increases the size of the nucleolus and activates p53 through the ribosomal-Mdm2 pathway.FATS is an E2-independent ubiquitin ligase that stabilizes p53 and promotes its activation in response to DNA damage.Recruitment of RPL11 at promoter sites of p53-regulated genes upon nucleolar stress through NEDD8 and in an Mdm2-dependent manner.
P2860
Q24295055-2690D681-EE64-4393-85E3-EFCB740B337BQ24296502-9D10068C-63D0-4C07-A153-AC41E1810F43Q24309310-316308BC-B26C-4172-A782-9134D3055888Q24313588-AB4FC231-732F-4603-89C4-F4E048912743Q24336529-6DEF9EF5-F09B-464F-B513-80B464920F90Q24653688-7C0E8DF0-CF44-41BB-8133-8375183B2A39Q28116100-95914144-8649-4E3B-91B2-646321B35AF9Q28508974-2DA16E27-DE2A-4135-B8C0-C42CEF574BE6Q33317275-F4F85D08-3D52-44F1-9920-68A9C2A4685CQ34020353-E851FE50-7211-4FDA-A918-4264AC0B99E1Q34056449-AFE95882-6DCF-47C9-816E-9FB100FD5131Q34166049-4B9743CF-26A5-418B-B419-6D0FA078A499Q34296531-952719B0-8816-4700-AD86-9BBA3CD4FEB6Q34342940-B43546B8-92CB-4F27-9353-7C58A2AA8DF9Q34452617-6175A5D7-5921-4E5B-A947-A103756954CFQ34458413-109AD978-D64F-433E-A6F3-2871CB0104D7Q34575503-95D2F8C4-49BB-47B3-B6BA-1B78641341ECQ34760621-4E395226-02F8-4E46-9DFE-20DAE0B3A3D5Q34863846-51AF6749-CEE5-45DE-8F0D-A57E237708C7Q34992991-3FE42963-A929-46C5-8561-40E1E38072D5Q35131633-0F678765-BB5E-48CB-BAA3-2773FC10A122Q35763247-BA6139AC-3245-4828-87AD-5DCB02964E0DQ35900948-4ECB423A-0477-408F-B2A6-9D2BB30A2671Q35916594-98E0D7B1-A3FE-40C1-BCCE-D6E2F29C7B4BQ36095718-D601A7B8-E7FC-43A1-A867-2CDDCDE8214AQ36152200-274B8D9D-813D-4C4C-B985-39EE6A9E6257Q36615629-2449465E-FD12-4A3B-B80D-93B4916C9D1EQ36657671-BD42FF38-7941-4EBA-BDB9-33723820DA46Q36967316-BC1DE737-BB98-4CE8-A7FF-8466FA50D5D6Q37174300-07516F20-4553-4F62-A345-49222708FA01Q37343700-C6B7F6AA-2207-4764-A51A-82ED7424D9F8Q37485899-0FB220D5-5ECC-4805-B34A-36642EAF7035Q37636014-CCDDA0F1-C61A-4899-BBF4-7B01AEF5BA48Q37992789-198D53D8-7C1F-4FB0-BAAD-4FBAB38338CEQ38043925-6280E99E-5FAA-4720-85D1-C2BC9D4F2FCCQ38229325-AB0C1221-3368-4A55-A885-CA424E4A2532Q38726399-5C5A2876-680E-4006-92D9-BBB4EB2BE72CQ38888153-6AF2835B-0BE3-4CFD-9E28-A01B379A0A76Q39062387-65D4E1FA-1BBA-4696-8913-80CE6A09D54EQ39256295-8CAB2781-CA65-4A72-A3C0-047961F68FD7
P2860
Regulation of p53 by the ubiquitin-conjugating enzymes UbcH5B/C in vivo
description
2004 nî lūn-bûn
@nan
2004 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Regulation of p53 by the ubiquitin-conjugating enzymes UbcH5B/C in vivo
@ast
Regulation of p53 by the ubiquitin-conjugating enzymes UbcH5B/C in vivo
@en
Regulation of p53 by the ubiquitin-conjugating enzymes UbcH5B/C in vivo
@nl
type
label
Regulation of p53 by the ubiquitin-conjugating enzymes UbcH5B/C in vivo
@ast
Regulation of p53 by the ubiquitin-conjugating enzymes UbcH5B/C in vivo
@en
Regulation of p53 by the ubiquitin-conjugating enzymes UbcH5B/C in vivo
@nl
prefLabel
Regulation of p53 by the ubiquitin-conjugating enzymes UbcH5B/C in vivo
@ast
Regulation of p53 by the ubiquitin-conjugating enzymes UbcH5B/C in vivo
@en
Regulation of p53 by the ubiquitin-conjugating enzymes UbcH5B/C in vivo
@nl
P2093
P3181
P356
P1476
Regulation of p53 by the ubiquitin-conjugating enzymes UbcH5B/C in vivo
@en
P2093
Alison Sparks
Dimitris P Xirodimas
Julie Wardrop
Lauren F Stevenson
Mark K Saville
Yvonne L Woods
P304
42169-42181
P3181
P356
10.1074/JBC.M403362200
P407
P577
2004-07-26T00:00:00Z