Regulation of p53 by the ubiquitin-conjugating enzymes UbcH5B/C in vivo - Wikidata - wikimedia - TriplyDB

Regulation of p53 by the ubiquitin-conjugating enzymes UbcH5B/C in vivo

Regulation of p53 by the ubiquitin-conjugating enzymes UbcH5B/C in vivo

http://www.wikidata.org/entity/Q28274471

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Turning the RING domain protein MdmX into an active ubiquitin-protein ligase The deubiquitinating enzyme USP2a regulates the p53 pathway by targeting Mdm2 Suppression of the deubiquitinating enzyme USP5 causes the accumulation of unanchored polyubiquitin and the activation of p53 Members of the E2D (UbcH5) family mediate the ubiquitination of the conserved cysteine of Pex5p, the peroxisomal import receptor A comprehensive framework of E2-RING E3 interactions of the human ubiquitin-proteasome system Ubc4/5 and c-Cbl continue to ubiquitinate EGF receptor after internalization to facilitate polyubiquitination and degradation Transcription factor TAFII250 promotes Mdm2-dependent turnover of p53 E2-25K/Hip-2 regulates caspase-12 in ER stress-mediated Abeta neurotoxicity Reconstitution of Mdm2-dependent post-translational modifications of p53 in yeast.The p53 orchestra: Mdm2 and Mdmx set the tone Autoactivation of the MDM2 E3 ligase by intramolecular interaction.MDM2, MDMX and p53 in oncogenesis and cancer therapy Mechanism of p53 stabilization by ATM after DNA damage.Limiting the power of p53 through the ubiquitin proteasome pathway.SLUG-induced elevation of D1 cyclin in breast cancer cells through the inhibition of its ubiquitination.Proteomic identification and analysis of K63-linked ubiquitin conjugates p53 directly transactivates Δ133p53α, regulating cell fate outcome in response to DNA damage Inhibition of UBE2D3 expression attenuates radiosensitivity of MCF-7 human breast cancer cells by increasing hTERT expression and activity.Microarray characterization of gene expression changes in blood during acute ethanol exposure Gene expression modifications in Wharton's Jelly mesenchymal stem cells promoted by prolonged in vitro culturing Regulation of p53 localization and activity by Ubc13.Identification and characterization of novel immunomodulatory bursal-derived pentapeptide-II (BPP-II)RNAi screen identifies UBE2D3 as a mediator of all-trans retinoic acid-induced cell growth arrest in human acute promyelocytic NB4 cells.Functional analysis and consequences of Mdm2 E3 ligase inhibition in human tumor cells Regulation of ubiquitin-proteasome system mediated degradation by cytosolic stress.Regulation of the Abundance of Kaposi's Sarcoma-Associated Herpesvirus ORF50 Protein by Oncoprotein MDM2 Accumulation of p53 via down-regulation of UBE2D family genes is a critical pathway for cadmium-induced renal toxicity Different Regulation of p53 Expression by Cadmium Exposure in Kidney, Liver, Intestine, Vasculature, and Brain Astrocytes Auto-ubiquitination of Mdm2 enhances its substrate ubiquitin ligase activity.Forty-eight hours of unloading and 24 h of reloading lead to changes in global gene expression patterns related to ubiquitination and oxidative stress in humans.Discovery, in vivo activity, and mechanism of action of a small-molecule p53 activator.Destabilization of Rb by human papillomavirus E7 is cell cycle dependent: E2-25K is involved in the proteolysis.Regulation of p53--insights into a complex process.Regulation of p53: a collaboration between Mdm2 and Mdmx.The exportomer: the peroxisomal receptor export machinery.Ubiquitination involved enzymes and cancer.Molecular Liver Cancer Prevention in Cirrhosis by Organ Transcriptome Analysis and Lysophosphatidic Acid Pathway Inhibition.The NEDD8 inhibitor MLN4924 increases the size of the nucleolus and activates p53 through the ribosomal-Mdm2 pathway.FATS is an E2-independent ubiquitin ligase that stabilizes p53 and promotes its activation in response to DNA damage.Recruitment of RPL11 at promoter sites of p53-regulated genes upon nucleolar stress through NEDD8 and in an Mdm2-dependent manner.

P2860

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P2860

Regulation of p53 by the ubiquitin-conjugating enzymes UbcH5B/C in vivo

http://www.wikidata.org/entity/Q28274471

description

2004 nî lūn-bûn

@nan

2004 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2004 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2004年の論文

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2004年論文

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2004年論文

@zh-hant

2004年論文

@zh-hk

2004年論文

@zh-mo

2004年論文

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2004年论文

@wuu

name

Regulation of p53 by the ubiquitin-conjugating enzymes UbcH5B/C in vivo

@ast

Regulation of p53 by the ubiquitin-conjugating enzymes UbcH5B/C in vivo

@en

Regulation of p53 by the ubiquitin-conjugating enzymes UbcH5B/C in vivo

@nl

type

label

Regulation of p53 by the ubiquitin-conjugating enzymes UbcH5B/C in vivo

@ast

Regulation of p53 by the ubiquitin-conjugating enzymes UbcH5B/C in vivo

@en

Regulation of p53 by the ubiquitin-conjugating enzymes UbcH5B/C in vivo

@nl

prefLabel

Regulation of p53 by the ubiquitin-conjugating enzymes UbcH5B/C in vivo

@ast

Regulation of p53 by the ubiquitin-conjugating enzymes UbcH5B/C in vivo

@en

Regulation of p53 by the ubiquitin-conjugating enzymes UbcH5B/C in vivo

@nl

P1433

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P1433

Journal of Biological Chemistry

P1476

Regulation of p53 by the ubiquitin-conjugating enzymes UbcH5B/C in vivo

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P2093

Alison Sparks

http://www.w3.org/2001/XMLSchema#string

Dimitris P Xirodimas

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Julie Wardrop

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Lauren F Stevenson

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Mark K Saville

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Yvonne L Woods

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42169-42181

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scholarly article

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1016014

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10.1074/JBC.M403362200

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40

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279

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Jean-Christophe Bourdon

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2004-07-26T00:00:00Z

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15280377

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