Autoactivation of the MDM2 E3 ligase by intramolecular interaction. - Wikidata - wikimedia - TriplyDB

Autoactivation of the MDM2 E3 ligase by intramolecular interaction.

Autoactivation of the MDM2 E3 ligase by intramolecular interaction.

http://www.wikidata.org/entity/Q34056449

about

Acetylation-dependent regulation of MDM2 E3 ligase activity dictates its oncogenic function.MDM2 oligomers: antagonizers of the guardian of the genome.Homozygous mdm2 SNP309 cancer cells with compromised transcriptional elongation at p53 target genes are sensitive to induction of p53-independent cell death.Autoinhibition of MDMX by intramolecular p53 mimicry Characterization of cancer-associated missense mutations in MDM2.Allosteric Interactions by p53 mRNA Govern HDM2 E3 Ubiquitin Ligase Specificity under Different Conditions.Ribosomal protein L4 is a novel regulator of the MDM2-p53 loop.Structural analysis of MDM2 RING separates degradation from regulation of p53 transcription activity.

P2860

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P2860

Autoactivation of the MDM2 E3 ligase by intramolecular interaction.

http://www.wikidata.org/entity/Q34056449

description

2014 nî lūn-bûn

@nan

2014 թուականի Մայիսին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի մայիսին հրատարակված գիտական հոդված

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2014年の論文

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2014年論文

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2014年論文

@zh-hant

2014年論文

@zh-hk

2014年論文

@zh-mo

2014年論文

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2014年论文

@wuu

name

Autoactivation of the MDM2 E3 ligase by intramolecular interaction.

@ast

Autoactivation of the MDM2 E3 ligase by intramolecular interaction.

@en

Autoactivation of the MDM2 E3 ligase by intramolecular interaction.

@nl

type

label

Autoactivation of the MDM2 E3 ligase by intramolecular interaction.

@ast

Autoactivation of the MDM2 E3 ligase by intramolecular interaction.

@en

Autoactivation of the MDM2 E3 ligase by intramolecular interaction.

@nl

prefLabel

Autoactivation of the MDM2 E3 ligase by intramolecular interaction.

@ast

Autoactivation of the MDM2 E3 ligase by intramolecular interaction.

@en

Autoactivation of the MDM2 E3 ligase by intramolecular interaction.

@nl

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Molecular and Cellular Biology

P1476

Autoactivation of the MDM2 E3 ligase by intramolecular interaction.

@en

P2093

Jiandong Chen

http://www.w3.org/2001/XMLSchema#string

Lihong Chen

http://www.w3.org/2001/XMLSchema#string

Qian Cheng

http://www.w3.org/2001/XMLSchema#string

Tanjing Song

http://www.w3.org/2001/XMLSchema#string

P2860

Intrinsically unstructured proteins and their functions

Function and structure of inherently disordered proteins

Mdm2 is a RING finger-dependent ubiquitin protein ligase for itself and p53

Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complex

Phosphorylation by casein kinase I promotes the turnover of the Mdm2 oncoprotein via the SCF(beta-TRCP) ubiquitin ligase

Structure of the Rb C-terminal domain bound to E2F1-DP1: a mechanism for phosphorylation-induced E2F release

Structural insights into NEDD8 activation of cullin-RING ligases: conformational control of conjugation

Structure of the MDM2 oncoprotein bound to the p53 tumor suppressor transactivation domain

Mdm2 promotes the rapid degradation of p53

Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53

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2800-2810

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scholarly article

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10.1128/MCB.00246-14

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15

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34

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2014-05-19T00:00:00Z

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4135571

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