Characterization of human Spartan/C1orf124, an ubiquitin-PCNA interacting regulator of DNA damage tolerance - Wikidata - wikimedia - TriplyDB

Characterization of human Spartan/C1orf124, an ubiquitin-PCNA interacting regulator of DNA damage tolerance

Characterization of human Spartan/C1orf124, an ubiquitin-PCNA interacting regulator of DNA damage tolerance

http://www.wikidata.org/entity/Q28275269

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PRP19 transforms into a sensor of RPA-ssDNA after DNA damage and drives ATR activation via a ubiquitin-mediated circuitry The Regulation of DNA Damage Tolerance by Ubiquitin and Ubiquitin-Like Modifiers Ring of Change: CDC48/p97 Drives Protein Dynamics at Chromatin Eukaryotic DNA polymerase ζ A widely employed germ cell marker is an ancient disordered protein with reproductive functions in diverse eukaryotes The transcriptome of the bowhead whale Balaena mysticetus reveals adaptations of the longest-lived mammal Role of PCNA and TLS polymerases in D-loop extension during homologous recombination in humans Human HLTF mediates postreplication repair by its HIRAN domain-dependent replication fork remodelling.DNA-dependent protease activity of human Spartan facilitates replication of DNA-protein crosslink-containing DNA.Spartan deficiency causes accumulation of Topoisomerase 1 cleavage complexes and tumorigenesis.SIVA1 directs the E3 ubiquitin ligase RAD18 for PCNA monoubiquitination.Spartan deficiency causes genomic instability and progeroid phenotypes.Single cell analysis of human RAD18-dependent DNA post-replication repair by alkaline bromodeoxyuridine comet assay.Mutations in SPRTN cause early onset hepatocellular carcinoma, genomic instability and progeroid features Relevance of simultaneous mono-ubiquitinations of multiple units of PCNA homo-trimers in DNA damage tolerance.A non-catalytic role of DNA polymerase η in recruiting Rad18 and promoting PCNA monoubiquitination at stalled replication forks Role of p97/VCP (Cdc48) in genome stability.The PCNA-associated protein PARI negatively regulates homologous recombination via the inhibition of DNA repair synthesis.DNA damage tolerance: a double-edged sword guarding the genome Mechanism and Regulation of DNA-Protein Crosslink Repair by the DNA-Dependent Metalloprotease SPRTN.The WD40-repeat protein-containing deubiquitinase complex: catalysis, regulation, and potential for therapeutic intervention.Mismatch repair protein MSH2 regulates translesion DNA synthesis following exposure of cells to UV radiation.Mechanisms of Post-Replication DNA Repair Quantitative microscopy uncovers ploidy changes during mitosis in live Drosophila embryos and their effect on nuclear size.Readers of PCNA modifications The identification of translesion DNA synthesis regulators: Inhibitors in the spotlight.Regulation of Rad6/Rad18 Activity During DNA Damage Tolerance.Strategic role of the ubiquitin-dependent segregase p97 (VCP or Cdc48) in DNA replication.Maintenance of Genome Integrity: How Mammalian Cells Orchestrate Genome Duplication by Coordinating Replicative and Specialized DNA Polymerases.Forging Ahead through Darkness: PCNA, Still the Principal Conductor at the Replication Fork.Regulation of error-prone translesion synthesis by Spartan/C1orf124.SPRTN is a mammalian DNA-binding metalloprotease that resolves DNA-protein crosslinks.Formation and repair of DNA-protein crosslink damage.Intelligent image-based in situ single-cell isolation.Maternal Haploid, a Metalloprotease Enriched at the Largest Satellite Repeat and Essential for Genome Integrity in Drosophila Embryos.The Expression of Checkpoint and DNA Repair Genes in Head and Neck Cancer as Possible Predictive Factors.DNA protein crosslink proteolysis repair: From yeast to premature ageing and cancer in humans

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Characterization of human Spartan/C1orf124, an ubiquitin-PCNA interacting regulator of DNA damage tolerance

http://www.wikidata.org/entity/Q28275269

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2012 nî lūn-bûn

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2012 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

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2012 թվականի նոյեմբերին հրատարակված գիտական հոդված

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年论文

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Characterization of human Spar ...... ulator of DNA damage tolerance

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Characterization of human Spar ...... ulator of DNA damage tolerance

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Characterization of human Spar ...... ulator of DNA damage tolerance

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Characterization of human Spar ...... ulator of DNA damage tolerance

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Characterization of human Spar ...... ulator of DNA damage tolerance

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Characterization of human Spar ...... ulator of DNA damage tolerance

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Characterization of human Spar ...... ulator of DNA damage tolerance

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Characterization of human Spar ...... ulator of DNA damage tolerance

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Characterization of human Spar ...... ulator of DNA damage tolerance

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Nucleic Acids Research

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Characterization of human Spar ...... ulator of DNA damage tolerance

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David Balogh

http://www.w3.org/2001/XMLSchema#string

Ildiko Hajdu

http://www.w3.org/2001/XMLSchema#string

Lajos Haracska

http://www.w3.org/2001/XMLSchema#string

Mark A Villamil

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Peter Burkovics

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Szilvia Juhasz

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Dysfunction of human Rad18 results in defective postreplication repair and hypersensitivity to multiple mutagens

Human SHPRH is a ubiquitin ligase for Mms2-Ubc13-dependent polyubiquitylation of proliferating cell nuclear antigen

UAF1 is a subunit of multiple deubiquitinating enzyme complexes

Spartan/C1orf124, a reader of PCNA ubiquitylation and a regulator of UV-induced DNA damage response

Polyubiquitination of proliferating cell nuclear antigen by HLTF and SHPRH prevents genomic instability from stalled replication forks

Human HLTF functions as a ubiquitin ligase for proliferating cell nuclear antigen polyubiquitination

RECQL5/Recql5 helicase regulates homologous recombination and suppresses tumor formation via disruption of Rad51 presynaptic filaments

Human SHPRH suppresses genomic instability through proliferating cell nuclear antigen polyubiquitination

Identification of the FANCI protein, a monoubiquitinated FANCD2 paralog required for DNA repair

The DNA Damage Response: Making It Safe to Play with Knives

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scholarly article

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849511

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10.1093/NAR/GKS850

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21

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40

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2012-09-16T00:00:00Z

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230870984

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22987070

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3510514

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