about
Biochemical characterization of a multidomain deubiquitinating enzyme Ubp15 and the regulatory role of its terminal domains.Characterization of human Spartan/C1orf124, an ubiquitin-PCNA interacting regulator of DNA damage toleranceCoupling DNA unwinding activity with primer synthesis in the bacteriophage T4 primosomeInteraction between the T4 helicase-loading protein (gp59) and the DNA polymerase (gp43): a locking mechanism to delay replication during replisome assembly.Processivity factor of DNA polymerase and its expanding role in normal and translesion DNA synthesisA selective USP1-UAF1 inhibitor links deubiquitination to DNA damage responses.The structure of a ring-opened proliferating cell nuclear antigen-replication factor C complex revealed by fluorescence energy transferStructurally distinct ubiquitin- and sumo-modified PCNA: implications for their distinct roles in the DNA damage response.Solution X-ray scattering combined with computational modeling reveals multiple conformations of covalently bound ubiquitin on PCNAA Thioester Substrate Binds to the Enzyme Arthrobacter Thioesterase in Two Ionization States; Evidence from Raman Difference SpectroscopyDeveloping peptide-based multivalent antagonists of proliferating cell nuclear antigen and a fluorescence-based PCNA binding assay.Regulation of polymerase exchange between Poleta and Poldelta by monoubiquitination of PCNA and the movement of DNA polymerase holoenzymeTransient kinetic analysis of USP2-catalyzed deubiquitination reveals a conformational rearrangement in the K48-linked diubiquitin substrateChemical Protein Ubiquitylation with Preservation of the Native Cysteine Residues.Regulatory role of ubiquitin in eukaryotic DNA translesion synthesis.An alternative clamp loading pathway via the T4 clamp loader gp44/62-DNA complex.Activity-based diubiquitin probes for elucidating the linkage specificity of deubiquitinating enzymesChemically ubiquitylated PCNA as a probe for eukaryotic translesion DNA synthesis.Structure of YciI from Haemophilus influenzae (HI0828) reveals a ferredoxin-like alpha/beta-fold with a histidine/aspartate centered catalytic site.Divergence of function in the hot dog fold enzyme superfamily: the bacterial thioesterase YciA.Structure, function, and mechanism of the phenylacetate pathway hot dog-fold thioesterase PaaI.'Screw-cap' clamp loader proteins that thread.Divergence in Ubiquitin Interaction and Catalysis among the Ubiquitin-Specific Protease Family Deubiquitinating Enzymes.Interaction between the T4 helicase loading protein (gp59) and the DNA polymerase (gp43): unlocking of the gp59-gp43-DNA complex to initiate assembly of a fully functional replisome.Cell-Permeable Activity-Based Ubiquitin Probes Enable Intracellular Profiling of Human DeubiquitinasesThe YbgC protein encoded by the ybgC gene of the tol-pal gene cluster of Haemophilus influenzae catalyzes acyl-coenzyme A thioester hydrolysisStructure-activity analysis of base and enzyme-catalyzed 4-hydroxybenzoyl coenzyme A hydrolysisThe oligomeric T4 primase is the functional form during replicationA noncanonical cysteine protease USP1 is activated through active site modulation by USP1-associated factor 1Chemical protein polyubiquitination reveals the role of a noncanonical polyubiquitin chain in DNA damage toleranceChemical Synthesis of Activity-Based Diubiquitin ProbesActivity-based ubiquitin-protein probes reveal target protein specificity of deubiquitinating enzymes
P50
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P50
description
researcher
@en
name
Zhihao Zhuang
@en
Zhihao Zhuang
@nl
type
label
Zhihao Zhuang
@en
Zhihao Zhuang
@nl
prefLabel
Zhihao Zhuang
@en
Zhihao Zhuang
@nl
P106
P31
P496
0000-0001-5047-9222