Membrane organization and tumorigenesis--the NF2 tumor suppressor, Merlin
about
A coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCF(beta-TRCP)Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth controlKibra functions as a tumor suppressor protein that regulates Hippo signaling in conjunction with Merlin and ExpandedMerlin/NF2 suppresses tumorigenesis by inhibiting the E3 ubiquitin ligase CRL4(DCAF1) in the nucleusNf2-Yap signaling controls the expansion of DRG progenitors and glia during DRG developmentTEAD transcription factors mediate the function of TAZ in cell growth and epithelial-mesenchymal transitionAngiomotin-like proteins associate with and negatively regulate YAP1TEAD mediates YAP-dependent gene induction and growth controlDrosophila lacking microRNA miR-278 are defective in energy homeostasisThe hippo signaling pathway in development and cancerIdentification and validation of oncogenes in liver cancer using an integrative oncogenomic approachRASopathies: unraveling mechanisms with animal modelsNeurofibromatosis type 2 protein, NF2: an uncoventional cell cycle regulator.Evasion of anti-growth signaling: A key step in tumorigenesis and potential target for treatment and prophylaxis by natural compounds.Model membranes to shed light on the biochemical and physical properties of ezrin/radixin/moesinUnfurling of the band 4.1, ezrin, radixin, moesin (FERM) domain of the merlin tumor suppressorStructural Basis of the Binding of Merlin FERM Domain to the E3 Ubiquitin Ligase Substrate Adaptor DCAF1Structural basis of DDB1-and-Cullin 4-associated Factor 1 (DCAF1) recognition by merlin/NF2 and its implication in tumorigenesis by CD44-mediated inhibition of merlin suppression of DCAF1 functionMerlin, a "magic" linker between extracellular cues and intracellular signaling pathways that regulate cell motility, proliferation, and survivalA crucial role of WW45 in developing epithelial tissues in the mouseLRRK2 phosphorylates moesin at threonine-558: characterization of how Parkinson's disease mutants affect kinase activityTumor suppressor Nf2/merlin drives Schwann cell changes following electromagnetic field exposure through Hippo-dependent mechanisms.Development of drug treatments for neurofibromatosis type 2-associated vestibular schwannoma.p75NTR is highly expressed in vestibular schwannomas and promotes cell survival by activating nuclear transcription factor κB.Consensus recommendations to accelerate clinical trials for neurofibromatosis type 2.mTORC1 inhibition delays growth of neurofibromatosis type 2 schwannoma.A deletion causing NF2 exon 9 skipping is associated with familial autosomal dominant intramedullary ependymoma.The NF2 tumor suppressor, Merlin, regulates epidermal development through the establishment of a junctional polarity complex.Loss of the tumor suppressor gene NF2, encoding merlin, constitutively activates integrin-dependent mTORC1 signaling.Loss of SOX10 function contributes to the phenotype of human Merlin-null schwannoma cells.Neurofibromatosis type 2 tumor suppressor protein, NF2, induces proteasome-mediated degradation of JC virus T-antigen in human glioblastomaMissense mutations in the NF2 gene result in the quantitative loss of merlin protein and minimally affect protein intrinsic function.Merlin knockdown in human Schwann cells: clues to vestibular schwannoma tumorigenesisGrowth inhibitory and anti-tumour activities of OSU-03012, a novel PDK-1 inhibitor, on vestibular schwannoma and malignant schwannoma cells.Microtubule-mediated transport of the tumor-suppressor protein Merlin and its mutants.YAP regulates cell mechanics by controlling focal adhesion assembly.The role of Drosophila Merlin in spermatogenesisIdentifying candidate genes affecting developmental time in Drosophila melanogaster: pervasive pleiotropy and gene-by-environment interaction.CD44 attenuates activation of the hippo signaling pathway and is a prime therapeutic target for glioblastomaThe nematode homologue of Mediator complex subunit 28, F28F8.5, is a critical regulator of C. elegans development.
P2860
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P2860
Membrane organization and tumorigenesis--the NF2 tumor suppressor, Merlin
description
2005 nî lūn-bûn
@nan
2005 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Membrane organization and tumorigenesis--the NF2 tumor suppressor, Merlin
@ast
Membrane organization and tumorigenesis--the NF2 tumor suppressor, Merlin
@en
Membrane organization and tumorigenesis--the NF2 tumor suppressor, Merlin
@nl
type
label
Membrane organization and tumorigenesis--the NF2 tumor suppressor, Merlin
@ast
Membrane organization and tumorigenesis--the NF2 tumor suppressor, Merlin
@en
Membrane organization and tumorigenesis--the NF2 tumor suppressor, Merlin
@nl
prefLabel
Membrane organization and tumorigenesis--the NF2 tumor suppressor, Merlin
@ast
Membrane organization and tumorigenesis--the NF2 tumor suppressor, Merlin
@en
Membrane organization and tumorigenesis--the NF2 tumor suppressor, Merlin
@nl
P3181
P356
P1433
P1476
Membrane organization and tumorigenesis--the NF2 tumor suppressor, Merlin
@en
P2093
Andrea I McClatchey
Marco Giovannini
P304
P3181
P356
10.1101/GAD.1335605
P407
P577
2005-10-01T00:00:00Z