Growth inhibitory and anti-tumour activities of OSU-03012, a novel PDK-1 inhibitor, on vestibular schwannoma and malignant schwannoma cells.
about
Childhood neurofibromatosis type 2 (NF2) and related disorders: from bench to bedside and biologically targeted therapies.Nonsteroidal anti-inflammatory medications are cytostatic against human vestibular schwannomas.p75NTR is highly expressed in vestibular schwannomas and promotes cell survival by activating nuclear transcription factor κB.Inhibition of c-Jun N-terminal kinase activity enhances vestibular schwannoma cell sensitivity to gamma irradiation.Preclinical validation of AR42, a novel histone deacetylase inhibitor, as treatment for vestibular schwannomas.AR42, a novel histone deacetylase inhibitor, as a potential therapy for vestibular schwannomas and meningiomas.Contribution of persistent C-Jun N-terminal kinase activity to the survival of human vestibular schwannoma cells by suppression of accumulation of mitochondrial superoxides.The inhibitory effect of honokiol, a natural plant product, on vestibular schwannoma cells.Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR cascade inhibitors: how mutations can result in therapy resistance and how to overcome resistance.Natural compounds as potential treatments of NF2-deficient schwannoma and meningioma: cucurbitacin D and goyazensolideProtein phosphatase 1 regulatory subunit 12A and catalytic subunit δ, new members in the phosphatidylinositide 3 kinase insulin-signaling pathway.Role of Merlin/NF2 inactivation in tumor biology.Advances in MRSA drug discovery: where are we and where do we need to be?The genome-wide expression profile of 1,2,3,4,6-penta-O-galloyl-β-D-glucose-treated MDA-MB-231 breast cancer cells: molecular target on cancer metabolism.Contemporary management of acoustic neuromas.Exploring the in vitro potential of celecoxib derivative AR-12 as an effective antiviral compound against four dengue virus serotypes.Histone deacetylase inhibitor AR-42 differentially affects cell-cycle transit in meningeal and meningioma cells, potently inhibiting NF2-deficient meningioma growth.Inhibition of MEK pathway in vestibular schwannoma cell culture.Inhibiting p21-Activated Kinase Induces Cell Death in Vestibular Schwannoma and Meningioma via Mitotic Catastrophe.The role of insulin-like growth factors signaling in merlin-deficient human schwannomas.Multistep phosphorylation by oncogenic kinases enhances the degradation of the NF2 tumor suppressor merlin.Targeting PDK1 for Chemosensitization of Cancer Cells.Disrupting Y-Box-Binding Protein 1 Function Using OSU-03012 Prevents Endometriosis Progression in In Vitro and In Vivo Models.[Pathogenesis and molecular pathology of vestibular schwannoma].[Current status of Akt in non-small cell lung cancer].Consensus recommendations for current treatments and accelerating clinical trials for patients with neurofibromatosis type 2
P2860
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P2860
Growth inhibitory and anti-tumour activities of OSU-03012, a novel PDK-1 inhibitor, on vestibular schwannoma and malignant schwannoma cells.
description
2009 nî lūn-bûn
@nan
2009 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Growth inhibitory and anti-tum ...... nd malignant schwannoma cells.
@ast
Growth inhibitory and anti-tum ...... nd malignant schwannoma cells.
@en
type
label
Growth inhibitory and anti-tum ...... nd malignant schwannoma cells.
@ast
Growth inhibitory and anti-tum ...... nd malignant schwannoma cells.
@en
prefLabel
Growth inhibitory and anti-tum ...... nd malignant schwannoma cells.
@ast
Growth inhibitory and anti-tum ...... nd malignant schwannoma cells.
@en
P2093
P2860
P1476
Growth inhibitory and anti-tum ...... nd malignant schwannoma cells.
@en
P2093
Abraham Jacob
Ching-Shih Chen
D Bradley Welling
Elena M Akhmametyeva
Long-Sheng Chang
Marco Giovannini
Mark D Packer
Samuel K Kulp
Tina X Lee
P2860
P304
P356
10.1016/J.EJCA.2009.03.013
P577
2009-04-07T00:00:00Z