Substrate specificity of heparanases from human hepatoma and platelets
about
Structural recognition by recombinant human heparanase that plays critical roles in tumor metastasis. Hierarchical sulfate groups with different effects and the essential target disulfated trisaccharide sequenceHeparanase enhances the generation of activated factor X in the presence of tissue factor and activated factor VIIA systems approach to prion diseaseTowards understanding the roles of heparan sulfate proteoglycans in Alzheimer's diseaseNewly generated heparanase knock-out mice unravel co-regulation of heparanase and matrix metalloproteinasesModulations of glypican-1 heparan sulfate structure by inhibition of endogenous polyamine synthesis. Mapping of spermine-binding sites and heparanase, heparin lyase, and nitric oxide/nitrite cleavage sites.Characterization of a novel intracellular heparanase that has a FERM domain.Heparanase and hepatocellular carcinoma: promoter or inhibitor?Versatile role of heparanase in inflammationUnraveling the specificity of heparanase utilizing synthetic substrates.Anticoagulant heparan sulfate precursor structures in F9 embryonal carcinoma cells.Highly sulfated nonreducing end-derived heparan sulfate domains bind fibroblast growth factor-2 with high affinity and are enriched in biologically active fractionsChemical Tumor Biology of Heparan Sulfate Proteoglycans.Dissociation between mature phenotype and impaired transmigration in dendritic cells from heparanase-deficient mice.Anti-heparanase aptamers as potential diagnostic and therapeutic agents for oral cancer.Development of novel single-stranded nucleic acid aptamers against the pro-angiogenic and metastatic enzyme heparanase (HPSE1)Molecular properties and involvement of heparanase in cancer metastasis and angiogenesis.Heparanase and coagulation-new insights.Structural characterization of human heparanase reveals insights into substrate recognition.A liquid chromatography-mass spectrometry-based approach to characterize the substrate specificity of mammalian heparanase.Mammalian heparanase: what is the message?Selective interaction of heparin with the variable region 3 within surface glycoprotein of laboratory-adapted feline immunodeficiency virusHeparin-protein interactions.Heparanase affects secretory granule homeostasis of murine mast cells through degrading heparinExpression of heparanase in normal, dysplastic, and neoplastic human colonic mucosa and stroma. Evidence for its role in colonic tumorigenesis.Rationale for clinical trials of coagulation: reactive drugs in hepatocellular carcinoma.Heparanase Overexpression Reduces Hepcidin Expression, Affects Iron Homeostasis and Alters the Response to Inflammation.Contribution of eIF-4E inhibition to the expression and activity of heparanase in human colon adenocarcinoma cell line: LS-174T.Deciphering mode of action of heparanase using structurally defined oligosaccharides.Overexpression of heparanase is associated with preeclampsia by inhibiting invasion of trophocytes.Impact of heparanase and the tumor microenvironment on cancer metastasis and angiogenesis: basic aspects and clinical applicationsHeparanase-A Link between Coagulation, Angiogenesis, and Cancer.Heparanase is overexpressed in lung cancer and correlates inversely with patient survivalMolecular structure of heparan sulfate from Spalax. Implications of heparanase and hypoxia.The non-anticoagulant heparin-like K5 polysaccharide derivative K5-N,OSepi attenuates myocardial ischaemia/reperfusion injuryNon-anticoagulant heparins and inhibition of cancer.Heparin-derived heparan sulfate mimics to modulate heparan sulfate-protein interaction in inflammation and cancer.Microbial heparin/heparan sulphate lyases: potential and applications.Heparan sulfate inhibitors and their therapeutic implications in inflammatory illnesses.Molecular engineering of glycosaminoglycan chemistry for biomolecule delivery.
P2860
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P2860
Substrate specificity of heparanases from human hepatoma and platelets
description
1998 nî lūn-bûn
@nan
1998 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Substrate specificity of heparanases from human hepatoma and platelets
@ast
Substrate specificity of heparanases from human hepatoma and platelets
@en
Substrate specificity of heparanases from human hepatoma and platelets
@nl
type
label
Substrate specificity of heparanases from human hepatoma and platelets
@ast
Substrate specificity of heparanases from human hepatoma and platelets
@en
Substrate specificity of heparanases from human hepatoma and platelets
@nl
prefLabel
Substrate specificity of heparanases from human hepatoma and platelets
@ast
Substrate specificity of heparanases from human hepatoma and platelets
@en
Substrate specificity of heparanases from human hepatoma and platelets
@nl
P2093
P3181
P356
P1476
Substrate specificity of heparanases from human hepatoma and platelets
@en
P2093
P304
P3181
P356
10.1074/JBC.273.30.18770
P407
P577
1998-07-24T00:00:00Z