Heparanase is overexpressed in lung cancer and correlates inversely with patient survival - Wikidata - wikimedia - TriplyDB

Heparanase is overexpressed in lung cancer and correlates inversely with patient survival

Heparanase is overexpressed in lung cancer and correlates inversely with patient survival

http://www.wikidata.org/entity/Q37059154

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Chemical Tumor Biology of Heparan Sulfate Proteoglycans.DAMPening inflammation by modulating TLR signalling.Heparanase enhances local and systemic osteolysis in multiple myeloma by upregulating the expression and secretion of RANKL Allele loss and down-regulation of heparanase gene are associated with the progression and poor prognosis of hepatocellular carcinoma.Prognostic value of heparanase expression and cellular localization in oral cancer.Pre-clinical and clinical significance of heparanase in Ewing's sarcoma.Genetic and epigenetic inactivation of extracellular superoxide dismutase promotes an invasive phenotype in human lung cancer by disrupting ECM homeostasis.Significance of heparanase in cancer and inflammation.The endoglycosidase heparanase enters the nucleus of T lymphocytes and modulates H3 methylation at actively transcribed genes via the interplay with key chromatin modifying enzymes Heparanase induced by advanced glycation end products (AGEs) promotes macrophage migration involving RAGE and PI3K/AKT pathway Heparanase inhibits osteoblastogenesis and shifts bone marrow progenitor cell fate in myeloma bone disease.Update in lung cancer 2008 Glycosylation alterations in lung and brain cancer.Heparanase overexpression participates in tumor growth of cervical cancer in vitro and in vivo.PI-88 inhibits postoperative recurrence of hepatocellular carcinoma via disrupting the surge of heparanase after liver resection.Heparanase expression correlates with poor survival in oral mucosal melanoma.Molecular analysis of single circulating tumour cells following long-term storage of clinical samples.Patient derived xenografts (PDX) predict an effective heparanase-based therapy for lung cancer.Heparan Sulfate and Heparan Sulfate Proteoglycans in Cancer Initiation and Progression

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Heparanase is overexpressed in lung cancer and correlates inversely with patient survival

http://www.wikidata.org/entity/Q37059154

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on September 2008

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

Heparanase is overexpressed in lung cancer and correlates inversely with patient survival

@en

Heparanase is overexpressed in ...... versely with patient survival.

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type

label

Heparanase is overexpressed in lung cancer and correlates inversely with patient survival

@en

Heparanase is overexpressed in ...... versely with patient survival.

@nl

prefLabel

Heparanase is overexpressed in lung cancer and correlates inversely with patient survival

@en

Heparanase is overexpressed in ...... versely with patient survival.

@nl

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Heparanase is overexpressed in lung cancer and correlates inversely with patient survival

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Esti Cohen

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Ilana Doweck

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Inna Naroditsky

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Israel Vlodavsky

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Lael A Best

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Neta Ilan

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Ofer Ben-Izhak

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Ran Kremer

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P2860

Mammalian heparanase: gene cloning, expression and function in tumor progression and metastasis

Heparanase uptake is mediated by cell membrane heparan sulfate proteoglycans

Heparanase induces vascular endothelial growth factor expression: correlation with p38 phosphorylation levels and Src activation

Processing and activation of latent heparanase occurs in lysosomes

Up-regulation of the lymphatic marker podoplanin, a mucin-type transmembrane glycoprotein, in human squamous cell carcinomas and germ cell tumors

New molecularly targeted therapies for lung cancer

VEGF controls endothelial-cell permeability by promoting the beta-arrestin-dependent endocytosis of VE-cadherin

Heparanase: structure, biological functions, and inhibition by heparin-derived mimetics of heparan sulfate

The impact of heparanese and heparin on cancer metastasis and angiogenesis

Substrate specificity of heparanases from human hepatoma and platelets

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1004-1011

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scholarly article

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10.1002/CNCR.23680

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2008-09-01T00:00:00Z

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