Androgen receptor coactivators lysine-specific histone demethylase 1 and four and a half LIM domain protein 2 predict risk of prostate cancer recurrence
about
The emerging role of histone lysine demethylases in prostate cancerG9a and Glp methylate lysine 373 in the tumor suppressor p53Phosphorylation of histone H3 at threonine 11 establishes a novel chromatin mark for transcriptional regulationLSD1/CoREST is an allosteric nanoscale clamp regulated by H3-histone-tail molecular recognition.Tumor necrosis factor receptor-associated factor 6 is an intranuclear transcriptional coactivator in osteoclastsTargeting histone methylation for cancer therapy: enzymes, inhibitors, biological activity and perspectivesHistone demethylase LSD1 controls the phenotypic plasticity of cancer cellsTherapeutic opportunities in Ewing sarcoma: EWS-FLI inhibition via LSD1 targetingThe role of histone demethylases in cancer therapyHistone lysine-specific methyltransferases and demethylases in carcinogenesis: new targets for cancer therapy and preventionHistone methylation restrains the expression of subtype-specific genes during terminal neuronal differentiation in Caenorhabditis elegansFormaldehyde in brain: an overlooked player in neurodegeneration?Assembly of methylated KDM1A and CHD1 drives androgen receptor-dependent transcription and translocationEpigenetic modulators as therapeutic targets in prostate cancerEpigenome-based personalized medicine in human cancerKDM1 class flavin-dependent protein lysine demethylasesLysine-specific demethylase 1 (LSD1) is highly expressed in ER-negative breast cancers and a biomarker predicting aggressive biologyLSD1 inhibition: a therapeutic strategy in cancer?Proline-, glutamic acid-, and leucine-rich protein-1/modulator of nongenomic activity of estrogen receptor enhances androgen receptor functions through LIM-only coactivator, four-and-a-half LIM-only protein 2Catalytic mechanism investigation of lysine-specific demethylase 1 (LSD1): a computational studyLSD1 regulates pluripotency of embryonic stem/carcinoma cells through histone deacetylase 1-mediated deacetylation of histone H4 at lysine 16The lysine specific demethylase-1 (LSD1/KDM1A) regulates VEGF-A expression in prostate cancerProtein-Protein Interactions Mediated by Helical Tertiary Structure Motifs.Impairment of prostate cancer cell growth by a selective and reversible lysine-specific demethylase 1 inhibitor.Sex differences in histone modifications in the neonatal mouse brainLysine-specific demethylase 1 (LSD1) Is required for the transcriptional repression of the telomerase reverse transcriptase (hTERT) gene.Prostate cancer-associated gene expression alterations determined from needle biopsies.Vitamin D and the epigenome.Cancer epigenetics: a brief review.Epigenetics: an emerging player in gastric cancerExploiting Epigenetic Alterations in Prostate Cancer.Reversing HOXA9 oncogene activation by PI3K inhibition: epigenetic mechanism and prognostic significance in human glioblastomaMelatonin exerts anti-oral cancer effect via suppressing LSD1 in patient-derived tumor xenograft models.Deficiency of the LIM-only protein FHL2 reduces intestinal tumorigenesis in Apc mutant mice.Epigenetic Signature: A New Player as Predictor of Clinically Significant Prostate Cancer (PCa) in Patients on Active Surveillance (AS)PKCα-mediated phosphorylation of LSD1 is required for presynaptic plasticity and hippocampal learning and memoryDoxorubicin enhances Snail/LSD1-mediated PTEN suppression in a PARP1-dependent mannerSilencing of the DNA mismatch repair gene MLH1 induced by hypoxic stress in a pathway dependent on the histone demethylase LSD1Chromatin proteins and modifications as drug targets.Epigenetics of prostate cancer and the prospect of identification of novel drug targets by RNAi screening of epigenetic enzymes.
P2860
Q21245762-87250238-74DB-4184-A854-B65CB6982115Q24298004-65951139-8B9B-43D4-8D80-977BA619B8CAQ24302392-36515616-CE4E-40AD-B351-B881A4978C41Q24623687-7D5DB621-6458-42A5-A0B5-C0DB76268680Q24651323-9DA81011-A340-4F97-8855-14C73DDBA084Q26744441-1D1880B2-6113-4590-9789-96A9CB95EFE7Q26745452-8A01C2DE-E058-4EB4-82A7-4AFFA6E59F10Q26768602-D8033910-69B4-46F3-B595-183FBEC13C77Q26864687-1DFE5A15-7646-488F-8E22-A93CD6F33EFFQ26994739-C8CB064C-9EAE-4F18-B797-6E058C1D3FCCQ27318351-8CDD1207-AE76-4B3D-80DD-D86265975BFCQ27691458-28EFF532-D83C-4DC8-B1B4-B7004D0BBA11Q27703586-1390A14B-6D70-4DCE-91C0-BA6455AAC543Q28071912-7B99624D-D450-4B1E-8351-923B77F01E35Q28083951-072803BF-9A24-4CFB-AD59-F329DAE04769Q28084876-AE8C6295-7DB6-4D3C-A720-2E7577DE21ADQ28269080-ACC36A19-2B34-4861-9D7C-9A07C3A337DAQ28274561-2C0ACE9E-845B-4A76-BF3C-55B6F3AF465EQ28280935-AB75F6B6-C78D-4125-B925-D095381779D9Q28477309-0BCFF2AD-2972-4FA8-B5AB-D073BD1641E0Q28593421-9F61E8F4-4432-4C1A-B2DC-7B33CD922BD8Q28687241-D8426873-5FD5-4032-84C5-13B562884E1BQ30378305-14D04958-FC2E-47D6-A64C-FDCDF69E5B74Q30414643-E2E0FBCF-7E03-428F-8B78-9FC1A9E7F170Q30439867-EC2BE6AE-DB54-4CFD-B88F-59873D33DE29Q33314914-C0FF54FB-2D0D-464E-BB35-6B6527D454BAQ33430210-BAAAC989-C34A-40A8-A6A2-38C8B8318E83Q33569349-F7ADE61A-7A2D-448D-9C1E-74C198D041B2Q33614190-82A551F7-2563-43FB-892F-FE50E1050375Q33718259-9999BCDB-D33E-4323-BD0D-7FDB4D7F7E0CQ33755160-ACF95367-50BD-4E5B-AFA6-346C44DF478AQ33771160-ECD6FCDA-B53E-418F-B971-1BCAD757E7DAQ33779673-A70D1064-FCDE-438E-B8FA-5EF419B628FBQ33815903-7837B77E-8456-4CD6-B2F7-F195EBDBEFFFQ33838513-B20D503C-BC02-45CD-831F-DCC5BB1A4D72Q33885079-B8964F7D-EAB8-4825-A29A-DCFBDD74D714Q33952953-9A8E92E8-47F0-4858-8E7E-8705893BE634Q33954219-4DD24BD4-C107-40AD-A1A2-85289AEADA49Q34038652-19D9FC97-248B-4A39-A677-27C72DA41B0AQ34084746-7C2A2C6F-027F-4402-BC7D-EF71D6D11F1F
P2860
Androgen receptor coactivators lysine-specific histone demethylase 1 and four and a half LIM domain protein 2 predict risk of prostate cancer recurrence
description
2006 nî lūn-bûn
@nan
2006 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Androgen receptor coactivators ...... of prostate cancer recurrence
@ast
Androgen receptor coactivators ...... of prostate cancer recurrence
@en
Androgen receptor coactivators ...... of prostate cancer recurrence
@nl
type
label
Androgen receptor coactivators ...... of prostate cancer recurrence
@ast
Androgen receptor coactivators ...... of prostate cancer recurrence
@en
Androgen receptor coactivators ...... of prostate cancer recurrence
@nl
prefLabel
Androgen receptor coactivators ...... of prostate cancer recurrence
@ast
Androgen receptor coactivators ...... of prostate cancer recurrence
@en
Androgen receptor coactivators ...... of prostate cancer recurrence
@nl
P2093
P3181
P1433
P1476
Androgen receptor coactivators ...... of prostate cancer recurrence
@en
P2093
Eric Metzger
Gerold Solleder
Jörg Ellinger
Lucia Gullotti
Nicolaus Friedrichs
Patrick J Bastian
Philip Kahl
Reinhard Buettner
Roland Schüle
Roland Vorreuther
P304
11341-11347
P3181
P356
10.1158/0008-5472.CAN-06-1570
P407
P577
2006-12-01T00:00:00Z