Histone deacetylase inhibitors: mechanisms and clinical significance in cancer: HDAC inhibitor-induced apoptosis
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Novel histone deacetylase inhibitors in clinical trials as anti-cancer agentsHistone deacetylase inhibitors: Potential in cancer therapyHistone deacetylase inhibitors in castration-resistant prostate cancer: molecular mechanism of action and recent clinical trialsTrials with 'epigenetic' drugs: an updateEpigenetic regulation of a murine retrotransposon by a dual histone modification markPreclinical validation of AR42, a novel histone deacetylase inhibitor, as treatment for vestibular schwannomas.Combination therapy with the histone deacetylase inhibitor LBH589 and radiation is an effective regimen for prostate cancer cells.Predicting Response to Histone Deacetylase Inhibitors Using High-Throughput Genomics.A phase I trial of panobinostat (LBH589) in patients with metastatic melanoma.Trichostatin A sensitizes cisplatin-resistant A549 cells to apoptosis by up-regulating death-associated protein kinaseDeveloping selective histone deacetylases (HDACs) inhibitors through ebselen and analogs.ZEB1 induces ER-α promoter hypermethylation and confers antiestrogen resistance in breast cancer.Discovery and preclinical validation of drug indications using compendia of public gene expression data.Chemopreventive mechanisms of α-keto acid metabolites of naturally occurring organoselenium compounds.Cancer genetics and epigenetics: two sides of the same coin?Bioinformatics analysis reveals potential candidate drugs for HCC.NBM-HD-1: A Novel Histone Deacetylase Inhibitor with Anticancer Activity.Identification of links between small molecules and miRNAs in human cancers based on transcriptional responses.Histone deacetylase inhibition and the regulation of cell growth with particular reference to liver pathobiology.The effects of DNA methylation and epigenetic factors on the expression of CD133 in ovarian cancers.Tissue-specific effects of valproic acid on DNA repair genes and apoptosis in postimplantation mouse embryos.Epigenetic repression of ribosomal RNA transcription by ROCK-dependent aberrant cytoskeletal organizationSynergism of heat shock protein 90 and histone deacetylase inhibitors in synovial sarcoma.The role of histone deacetylases in prostate cancer.Preclinical activity of the rational combination of selumetinib (AZD6244) in combination with vorinostat in KRAS-mutant colorectal cancer models.Epigenetics in human melanoma.Down-modulation of SEL1L, an unfolded protein response and endoplasmic reticulum-associated degradation protein, sensitizes glioma stem cells to the cytotoxic effect of valproic acid.The histone deacetylase inhibitor trichostatin A alters microRNA expression profiles in apoptosis-resistant breast cancer cells.Small-molecule chromatin-modifying agents: therapeutic applications.AML1-ETO driven acute leukemia: insights into pathogenesis and potential therapeutic approaches.Roles of histone methyl-modifying enzymes in development and progression of cancer.Profile of selumetinib and its potential in the treatment of melanoma.Natural products as zinc-dependent histone deacetylase inhibitors.Development of Novel Anti-Cd20 Monoclonal Antibodies and Modulation in Cd20 Levels on Cell Surface: Looking to Improve Immunotherapy ResponseInhibition of Plk1 and Cyclin B1 expression results in panobinostat-induced G₂ delay and mitotic defects.A novel hydroxysuberamide derivative potentiates MG132-mediated anticancer activity against human hormone refractory prostate cancers--the role of histone deacetylase and endoplasmic reticulum stress.Selenium-containing histone deacetylase inhibitors for melanoma management.DNMT inhibitors and HDAC inhibitors regulate E-cadherin and Bcl-2 expression in endometrial carcinoma in vitro and in vivo.Mule determines the apoptotic response to HDAC inhibitors by targeted ubiquitination and destruction of HDAC2.Itch/AIP4-independent proteasomal degradation of cFLIP induced by the histone deacetylase inhibitor SAHA sensitizes breast tumour cells to TRAIL.
P2860
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P2860
Histone deacetylase inhibitors: mechanisms and clinical significance in cancer: HDAC inhibitor-induced apoptosis
description
2008 nî lūn-bûn
@nan
2008 թուականին հրատարակուած գիտական յօդուած
@hyw
2008 թվականին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Histone deacetylase inhibitors ...... AC inhibitor-induced apoptosis
@ast
Histone deacetylase inhibitors ...... AC inhibitor-induced apoptosis
@en
Histone deacetylase inhibitors ...... AC inhibitor-induced apoptosis
@nl
type
label
Histone deacetylase inhibitors ...... AC inhibitor-induced apoptosis
@ast
Histone deacetylase inhibitors ...... AC inhibitor-induced apoptosis
@en
Histone deacetylase inhibitors ...... AC inhibitor-induced apoptosis
@nl
prefLabel
Histone deacetylase inhibitors ...... AC inhibitor-induced apoptosis
@ast
Histone deacetylase inhibitors ...... AC inhibitor-induced apoptosis
@en
Histone deacetylase inhibitors ...... AC inhibitor-induced apoptosis
@nl
P3181
P1476
Histone deacetylase inhibitors ...... AC inhibitor-induced apoptosis
@en
P2093
Rakesh K Srivastava
Sharmila Shankar
P304
P3181
P356
10.1007/978-1-4020-6554-5_13
P407
P577
2008-01-01T00:00:00Z