PTEN mutations and microsatellite instability in complex atypical hyperplasia, a precursor lesion to uterine endometrioid carcinoma
about
The tumor-suppressor activity of PTEN is regulated by its carboxyl-terminal regionHormonal therapy in advanced or recurrent endometrial cancerK-ras mutations appear in the premalignant phase of both microsatellite stable and unstable endometrial carcinogenesishMLH1 promoter hypermethylation is an early event in human endometrial tumorigenesisTherapeutic options for management of endometrial hyperplasiaIntegrated genomic characterization of endometrial carcinomaThe synergistic effect of Mig-6 and Pten ablation on endometrial cancer development and progression.Role of the clinical pathology laboratory in the evaluation of endometrial carcinomas for Lynch syndromeEpithelial-to-Mesenchymal Transition in the Female Reproductive Tract: From Normal Functioning to Disease Pathology.Expression of the DMBT1 gene is frequently suppressed in human lung cancer.A novel three-dimensional culture system of polarized epithelial cells to study endometrial carcinogenesis.What we could do now: molecular pathology of gynaecological cancer.PTEN expression causes feedback upregulation of insulin receptor substrate 2Steroid hormone intervenes in the endometrial tumorigenesis of pten ablation.Mig-6 suppresses endometrial cancer associated with Pten deficiency and ERK activation.Hereditary ovarian carcinoma: heterogeneity, molecular genetics, pathology, and management.Adenovirus mediated homozygous endometrial epithelial Pten deletion results in aggressive endometrial carcinoma.Diagnosis of premalignant endometrial disease.Genetic imbalances in precursor lesions of endometrial cancer detected by comparative genomic hybridization.Mutation and expression analyses reveal differential subcellular compartmentalization of PTEN in endocrine pancreatic tumors compared to normal islet cellsImmunohistochemical evidence of loss of PTEN expression in primary ductal adenocarcinomas of the breast.Considerations when analyzing the methylation status of PTEN tumor suppressor gene.DNA mismatch repair deficiency accelerates endometrial tumorigenesis in Pten heterozygous mice.Endometrial tumorigenesis in Pten(+/-) mice is independent of coexistence of estrogen and estrogen receptor α.The genomics and genetics of endometrial cancer.Characterization of EN-1078D, a poorly differentiated human endometrial carcinoma cell line: a novel tool to study endometrial invasion in vitroThe PTEN-Akt pathway impacts the integrity and composition of mitotic centrosomesRelationship between PTEN, DNA mismatch repair, and tumor histotype in endometrial carcinoma: retained positive expression of PTEN preferentially identifies sporadic non-endometrioid carcinomasOviduct-specific glycoprotein is a molecular marker for invasion in endometrial tumorigenesis identified using a relevant mouse model.The Synergistic Effect of Conditional Pten Loss and Oncogenic K-ras Mutation on Endometrial Cancer Development Occurs via Decreased Progesterone Receptor Action.Tumor genetic analyses of patients with metastatic melanoma treated with the BRAF inhibitor dabrafenib (GSK2118436).Through the glass darkly: intraepithelial neoplasia, top-down differentiation, and the road to ovarian cancer.Discordant Mutations in Paired Primary and Metastatic Endometrial Adenocarcinomas Identified by Semiconductor-Based Sequencing for Rapid Cancer Genotyping.Oncogenic HrasG12V expression plus knockdown of Cdkn2a using ecotropic lentiviral vectors induces high-grade endometrial stromal sarcoma.Three-dimensional nuclear telomere architecture changes during endometrial carcinoma development.The allosteric AKT inhibitor, MK2206, decreases tumor growth and invasion in patient derived xenografts of endometrial cancer.Loss of PTEN in high grade advanced stage triple negative breast ductal cancers in African American women.Genetic analysis and phosphoinositide 3-kinase/protein kinase B signaling pathway status in ovarian endometrioid borderline tumor samples.The uterine epithelial loss of Pten is inefficient to induce endometrial cancer with intact stromal Pten
P2860
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P2860
PTEN mutations and microsatellite instability in complex atypical hyperplasia, a precursor lesion to uterine endometrioid carcinoma
description
1998 nî lūn-bûn
@nan
1998 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
PTEN mutations and microsatell ...... uterine endometrioid carcinoma
@ast
PTEN mutations and microsatell ...... uterine endometrioid carcinoma
@en
PTEN mutations and microsatell ...... uterine endometrioid carcinoma
@nl
type
label
PTEN mutations and microsatell ...... uterine endometrioid carcinoma
@ast
PTEN mutations and microsatell ...... uterine endometrioid carcinoma
@en
PTEN mutations and microsatell ...... uterine endometrioid carcinoma
@nl
prefLabel
PTEN mutations and microsatell ...... uterine endometrioid carcinoma
@ast
PTEN mutations and microsatell ...... uterine endometrioid carcinoma
@en
PTEN mutations and microsatell ...... uterine endometrioid carcinoma
@nl
P2093
P1433
P1476
PTEN mutations and microsatell ...... uterine endometrioid carcinoma
@en
P2093
P304
P407
P577
1998-08-01T00:00:00Z