Metabolic modulation of glioblastoma with dichloroacetate
about
Pyruvate dehydrogenase kinase as a novel therapeutic target in oncologyMetabolic targeting of lactate efflux by malignant glioma inhibits invasiveness and induces necrosis: an in vivo studyNovel drugs that target the metabolic reprogramming in renal cell cancerRole of Redox Status in Development of GlioblastomaSLC transporters as a novel class of tumour suppressors: identity, function and molecular mechanismsIntegration of Mitochondrial Targeting for Molecular Cancer TherapeuticsTargeting Tumor Metabolism for Cancer Treatment: Is Pyruvate Dehydrogenase Kinases (PDKs) a Viable Anticancer Target?The Efficacy of Ketogenic Diet and Associated Hypoglycemia as an Adjuvant Therapy for High-Grade Gliomas: A Review of the LiteraturePyruvate Dehydrogenase Kinases: Therapeutic Targets for Diabetes and CancersCancer metabolic reprogramming: importance, main features, and potentials for precise targeted anti-cancer therapiesRegulation of mitochondrial function by voltage dependent anion channels in ethanol metabolism and the Warburg effectIs cancer a metabolic disease?What is good for the circulation also lessens cancer riskPrinciples of targeting endothelial cell metabolism to treat angiogenesis and endothelial cell dysfunction in diseaseRestoration of mitochondria function as a target for cancer therapyNovel therapeutic targets of tumor metabolismIncreasing Superoxide Production and the Labile Iron Pool in Tumor Cells may Sensitize Them to Extracellular AscorbateThe emerging paradigm of network medicine in the study of human diseaseShort-Term Differentiation of Glioblastoma Stem Cells Induces Hypoxia Tolerance.Structure-guided Development of Specific Pyruvate Dehydrogenase Kinase Inhibitors Targeting the ATP-binding PocketHeterogeneity of glycolysis in cancers and therapeutic opportunities.The Warburg effect: 80 years onThe role of Fatty Acid oxidation in the metabolic reprograming of activated t-cellsAdipose tissue dysfunction and its effects on tumor metabolismMolecular Connections between Cancer Cell Metabolism and the Tumor MicroenvironmentEmerging concepts in the molecular basis of pulmonary arterial hypertension: part I: metabolic plasticity and mitochondrial dynamics in the pulmonary circulation and right ventricle in pulmonary arterial hypertensionDichloroacetate inhibits neuroblastoma growth by specifically acting against malignant undifferentiated cellsPDK4 protein promotes tumorigenesis through activation of cAMP-response element-binding protein (CREB)-Ras homolog enriched in brain (RHEB)-mTORC1 signaling cascadePrenatal and postnatal expression of glutathione transferase ζ 1 in human liver and the roles of haplotype and subject age in determining activity with dichloroacetateCombination of sulindac and dichloroacetate kills cancer cells via oxidative damageComprehensive analysis of glycolytic enzymes as therapeutic targets in the treatment of glioblastomaMitochondrial Akt Regulation of Hypoxic Tumor ReprogrammingRepurposing phenformin for the targeting of glioma stem cells and the treatment of glioblastomaChemical metabolic inhibitors for the treatment of blood-borne cancersPro-haloacetate Nanoparticles for Efficient Cancer Therapy via Pyruvate Dehydrogenase Kinase ModulationIncreased mitochondrial activity in renal proximal tubule cells from young spontaneously hypertensive ratsThe right ventricle in pulmonary arterial hypertension: disorders of metabolism, angiogenesis and adrenergic signaling in right ventricular failure.Fatal Liver and Bone Marrow Toxicity by Combination Treatment of Dichloroacetate and Artesunate in a Glioblastoma Multiforme Patient: Case Report and Review of the Literature1,25-dihydroxyvitamin D regulation of glucose metabolism in Harvey-ras transformed MCF10A human breast epithelial cellsTeaching the basics of cancer metabolism: Developing antitumor strategies by exploiting the differences between normal and cancer cell metabolism
P2860
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P2860
Metabolic modulation of glioblastoma with dichloroacetate
description
2010 nî lūn-bûn
@nan
2010 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Metabolic modulation of glioblastoma with dichloroacetate
@ast
Metabolic modulation of glioblastoma with dichloroacetate
@en
Metabolic modulation of glioblastoma with dichloroacetate
@nl
type
label
Metabolic modulation of glioblastoma with dichloroacetate
@ast
Metabolic modulation of glioblastoma with dichloroacetate
@en
Metabolic modulation of glioblastoma with dichloroacetate
@nl
prefLabel
Metabolic modulation of glioblastoma with dichloroacetate
@ast
Metabolic modulation of glioblastoma with dichloroacetate
@en
Metabolic modulation of glioblastoma with dichloroacetate
@nl
P2093
P2860
P3181
P1476
Metabolic modulation of glioblastoma with dichloroacetate
@en
P2093
B Abdulkarim
E D Michelakis
G Sutendra
K C Petruk
M S McMurtry
P2860
P304
P3181
P356
10.1126/SCITRANSLMED.3000677
P407
P577
2010-05-01T00:00:00Z