TLS facilitates transport of mRNA encoding an actin-stabilizing protein to dendritic spines
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Chronic cocaine-regulated epigenomic changes in mouse nucleus accumbens.Abundant FUS-immunoreactive pathology in neuronal intermediate filament inclusion diseaseALS-associated fused in sarcoma (FUS) mutations disrupt Transportin-mediated nuclear importA new subtype of frontotemporal lobar degeneration with FUS pathologyTLS inhibits RNA polymerase III transcriptionDysregulated axonal RNA translation in amyotrophic lateral sclerosisFUS-mediated regulation of alternative RNA processing in neurons: insights from global transcriptome analysisAlterations in stress granule dynamics driven by TDP-43 and FUS: a link to pathological inclusions in ALS?Molecular motor proteins and amyotrophic lateral sclerosisCytoplasmic sequestration of FUS/TLS associated with ALS alters histone marks through loss of nuclear protein arginine methyltransferase 1.Early lethality and neuronal proteinopathy in mice expressing cytoplasm-targeted FUS that lacks the RNA recognition motif.FUS transgenic rats develop the phenotypes of amyotrophic lateral sclerosis and frontotemporal lobar degenerationTransportin1: a marker of FTLD-FUSFUS-NLS/Transportin 1 complex structure provides insights into the nuclear targeting mechanism of FUS and the implications in ALSSelective frontoinsular von Economo neuron and fork cell loss in early behavioral variant frontotemporal dementia.FUS is sequestered in nuclear aggregates in ALS patient fibroblasts.The ALS disease protein TDP-43 is actively transported in motor neuron axons and regulates axon outgrowth.Overexpression of human wild-type FUS causes progressive motor neuron degeneration in an age- and dose-dependent fashion.FUS/TLS assembles into stress granules and is a prosurvival factor during hyperosmolar stressGene expression responses to FUS, EWS, and TAF15 reduction and stress granule sequestration analyses identifies FET-protein non-redundant functions.The multifunctional FUS, EWS and TAF15 proto-oncoproteins show cell type-specific expression patterns and involvement in cell spreading and stress response.The TET family of proteins: functions and roles in disease.Distinct pathological subtypes of FTLD-FUS.Multistep process of FUS aggregation in the cell cytoplasm involves RNA-dependent and RNA-independent mechanisms.The tip of the iceberg: RNA-binding proteins with prion-like domains in neurodegenerative disease.Fus gene mutations in familial and sporadic amyotrophic lateral sclerosis.Functions of FUS/TLS from DNA repair to stress response: implications for ALS.Mutant FUS proteins that cause amyotrophic lateral sclerosis incorporate into stress granulesNuclear localization sequence of FUS and induction of stress granules by ALS mutants.A network of RNA and protein interactions in Fronto Temporal Dementia.Normal and functional TP53 in genetically stable myxoid/round cell liposarcoma.Linking RNA Dysfunction and Neurodegeneration in Amyotrophic Lateral Sclerosis.Understanding the role of TDP-43 and FUS/TLS in ALS and beyond.Aging--RNA in development and disease.Motor neuron apoptosis and neuromuscular junction perturbation are prominent features in a Drosophila model of Fus-mediated ALSTranslocated in liposarcoma regulates the distribution and function of mammalian enabled, a modulator of actin dynamics.Altered mRNP granule dynamics in FTLD pathogenesis.Mutations in FUS cause FALS and SALS in French and French Canadian populationsEntorhinal cortical neurons are the primary targets of FUS mislocalization and ubiquitin aggregation in FUS transgenic rats.TDP-43 and FUS en route from the nucleus to the cytoplasm.
P2860
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P2860
TLS facilitates transport of mRNA encoding an actin-stabilizing protein to dendritic spines
description
2005 nî lūn-bûn
@nan
2005 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
TLS facilitates transport of m ...... ng protein to dendritic spines
@ast
TLS facilitates transport of m ...... ng protein to dendritic spines
@en
TLS facilitates transport of m ...... ng protein to dendritic spines
@nl
type
label
TLS facilitates transport of m ...... ng protein to dendritic spines
@ast
TLS facilitates transport of m ...... ng protein to dendritic spines
@en
TLS facilitates transport of m ...... ng protein to dendritic spines
@nl
prefLabel
TLS facilitates transport of m ...... ng protein to dendritic spines
@ast
TLS facilitates transport of m ...... ng protein to dendritic spines
@en
TLS facilitates transport of m ...... ng protein to dendritic spines
@nl
P2093
P3181
P356
P1476
TLS facilitates transport of m ...... ng protein to dendritic spines
@en
P2093
Ritsuko Fujii
Toru Takumi
P304
P3181
P356
10.1242/JCS.02692
P407
P577
2005-12-15T00:00:00Z