Regulation of Skp2 expression and activity and its role in cancer progression
about
sameAs
Domain-specific c-Myc ubiquitylation controls c-Myc transcriptional and apoptotic activityPharmacological inactivation of Skp2 SCF ubiquitin ligase restricts cancer stem cell traits and cancer progressionDeacetylation of FOXO3 by SIRT1 or SIRT2 leads to Skp2-mediated FOXO3 ubiquitination and degradationThe Skp2-SCF E3 ligase regulates Akt ubiquitination, glycolysis, herceptin sensitivity, and tumorigenesisThe Importance of Ubiquitin E3 Ligases, SCF and APC/C, in Human CancersTargeting the ubiquitin pathway for cancer treatmentPosttranslational regulation of Akt in human cancerXenohormetic and anti-aging activity of secoiridoid polyphenols present in extra virgin olive oil: a new family of gerosuppressant agentsThe CREB-binding protein inhibitor ICG-001 suppresses pancreatic cancer growth.SCF-FBXO31 E3 ligase targets DNA replication factor Cdt1 for proteolysis in the G2 phase of cell cycle to prevent re-replication.Beta-estradiol attenuates hypoxic pulmonary hypertension by stabilizing the expression of p27kip1 in rats.SKP2 cooperates with N-Ras or AKT to induce liver tumor development in mice.Skp2 is a promising therapeutic target in breast cancer.Novel ARF/p53-independent senescence pathways in cancer repression.Metformin suppresses growth of human head and neck squamous cell carcinoma via global inhibition of protein translation.Skp2 expression unfavorably impacts survival in resectable esophageal squamous cell carcinoma.Prodigiosin down-regulates SKP2 to induce p27(KIP1) stabilization and antiproliferation in human lung adenocarcinoma cells.Skp2 E3 ligase integrates ATM activation and homologous recombination repair by ubiquitinating NBS1.Foxo3a transcription factor is a negative regulator of Skp2 and Skp2 SCF complex.The Role of F-Box Proteins during Viral Infection.Ubiquitination-mediated degradation of cell cycle-related proteins by F-box proteinsTRIP6 regulates p27 KIP1 to promote tumorigenesis.RIG-I inhibits pancreatic β cell proliferation through competitive binding of activated Src.Skp2-RNAi suppresses proliferation and migration of gallbladder carcinoma cells by enhancing p27 expression.Skp2-dependent ubiquitination and activation of LKB1 is essential for cancer cell survival under energy stress.Novel roles of Skp2 E3 ligase in cellular senescence, cancer progression, and metastasis.The Complex Relationship between Liver Cancer and the Cell Cycle: A Story of Multiple Regulations.MYC degradationUbiquitination involved enzymes and cancer.Recent advances in SCF ubiquitin ligase complex: Clinical implicationsMolecular mechanism of anticancer effect of Sclerotium rolfsii lectin in HT29 cells involves differential expression of genes associated with multiple signaling pathways: A microarray analysis.SKP2 overexpression is associated with increased serine 10 phosphorylation of p27 (pSer10p27) in triple-negative breast cancer.MYC Modulation around the CDK2/p27/SKP2 AxisSkp2 deficiency restricts the progression and stem cell features of castration-resistant prostate cancer by destabilizing Twistp53, SKP2, and DKK3 as MYCN Target Genes and Their Potential Therapeutic Significance.Id2a functions to limit Notch pathway activity and thereby influence the transition from proliferation to differentiation of retinoblasts during zebrafish retinogenesis.Fadd and Skp2 are possible downstream targets of RUNX1-EVI1.Dysregulated expression of SKP2 and its role in hematological malignancies.The F-box protein FBXL18 promotes glioma progression by promoting K63-linked ubiquitination of Akt.14-3-3β Depletion Drives a Senescence Program in Glioblastoma Cells Through the ERK/SKP2/p27 Pathway.
P2860
Q24307490-D253C24E-5D69-494C-B70F-064F4E30D7BCQ24314416-CFE44E19-49B8-4E51-BDA1-4C47406B0E7EQ24322745-5E58BD32-7541-45E9-A94D-627B26CFFC4FQ24613186-C8FD7052-0B9C-4FD3-8B3E-8CCBF793D91BQ26777305-C5B5FA53-A1F8-44CE-B3E5-13D61749EBD2Q26866185-C43ED37C-7E1B-4716-B3E6-96F94FB84EFDQ27027815-63460848-8591-47A8-AFBC-B455D8EE5CF0Q28395443-3D09A0D6-1EE0-451C-B7BB-EF514DA84271Q34041619-3326CEF3-4192-469D-9C17-58F0E7C9B672Q34073816-8A8B8834-3165-4F8D-B2A1-AA0A823E1C94Q34499303-CB36FF55-2D00-4FF2-9774-8DC399B6A372Q35273519-8540468E-291C-4655-AA9F-8C70D3819713Q35687208-D1E17200-00D8-4B9F-8D7C-0DF67E6E4FFBQ35810716-FCA7F9B0-8CFB-4A2F-9706-DE98AA75C0D2Q35954892-967FA700-C30B-4784-9029-3C82194D7313Q35972768-3CA755B2-045A-409E-94F2-140C453C6997Q36110509-7C9EFBA1-F6CB-4A2B-984B-205E6483697BQ36455995-BA528681-6A79-443E-8536-7506E7F4EE36Q36508271-ED685E67-F7CC-48E8-859E-0D62CF3CC651Q36656176-D6BED1A0-0DD2-48C6-891C-F5BDF3A2B34CQ36703456-AA84C4F8-8218-4CEE-8464-FE3577861195Q36759860-96E32609-7936-45C9-9798-96DF0C811512Q37044602-AD9C9446-B61B-44FF-A322-0F81B3A2E685Q37087498-7912B601-72D3-44FB-A7D0-C992873D5199Q37680723-AA702700-C7FE-494A-B594-8B4F0D5A5D10Q37971404-BBA8EB29-81D1-4915-B635-89EC66B41447Q38178032-96DC79C0-473C-499A-9239-9F715F684A5AQ38193043-32170524-6D01-4E4C-BD11-FAD069B48440Q38229325-06AFB7C7-8692-4B28-93DA-A69B747ACD08Q38828721-2221491B-39BD-4B2B-BCDB-AB6D82E41FB6Q38837139-CE5DC0A6-225D-469E-BDFF-582763337CB1Q39032869-68AA587B-F228-473B-B087-62C4E4E514D1Q39406924-ACA40BBE-0918-43FF-891C-68B80D827080Q41686942-F9FAB07F-2A5D-48DE-8C38-C3A21146999FQ42362115-53A14A1F-6C8B-4237-A1EF-F0E7D9401736Q42410840-175C5AE4-79AE-4B1B-B6BD-ED07041FAE4CQ44175679-83F859CC-CE3F-4C36-8A3A-D6A083DA4267Q47967824-5F813337-F50C-4563-9A40-B51DE2B159B3Q48403231-77305792-C985-4E01-B88B-06F7B4A731D5Q48859144-FF3DF5E4-AF75-4109-BFCF-E3C5DC91CFB1
P2860
Regulation of Skp2 expression and activity and its role in cancer progression
description
2010 nî lūn-bûn
@nan
2010 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Regulation of Skp2 expression and activity and its role in cancer progression
@ast
Regulation of Skp2 expression and activity and its role in cancer progression
@en
Regulation of Skp2 expression and activity and its role in cancer progression
@nl
type
label
Regulation of Skp2 expression and activity and its role in cancer progression
@ast
Regulation of Skp2 expression and activity and its role in cancer progression
@en
Regulation of Skp2 expression and activity and its role in cancer progression
@nl
altLabel
Regulation of Skp2 Expression and Activity and Its Role in Cancer Progression
@en
prefLabel
Regulation of Skp2 expression and activity and its role in cancer progression
@ast
Regulation of Skp2 expression and activity and its role in cancer progression
@en
Regulation of Skp2 expression and activity and its role in cancer progression
@nl
P2093
P921
P3181
P356
P1476
Regulation of Skp2 expression and activity and its role in cancer progression
@en
P2093
Hui-Kuan Lin
Szu-Wei Lee
P304
P3181
P356
10.1100/TSW.2010.89
P407
P5008
P577
2010-06-01T00:00:00Z