Tumour amplified kinase STK15/BTAK induces centrosome amplification, aneuploidy and transformation
about
The role of protein elongation factor eEF1A2 in ovarian cancerDownregulation of the anaphase-promoting complex (APC)7 in invasive ductal carcinomas of the breast and its clinicopathologic relationshipsThe p53-targeting human phosphatase hCdc14A interacts with the Cdk1/cyclin B complex and is differentially expressed in human cancersWhen the genome plays dice: circumvention of the spindle assembly checkpoint and near-random chromosome segregation in multipolar cancer cell mitosesMale germ cell-associated kinase is overexpressed in prostate cancer cells and causes mitotic defects via deregulation of APC/CCDH1SIRT2 maintains genome integrity and suppresses tumorigenesis through regulating APC/C activityTankyrase-1 assembly to large protein complexes blocks its telomeric functionTACC1-chTOG-Aurora A protein complex in breast cancerIdentification of Ski as a target for Aurora A kinaseAurora kinase-A inactivates DNA damage-induced apoptosis and spindle assembly checkpoint response functions of p73Phosphorylation and stabilization of HURP by Aurora-A: implication of HURP as a transforming target of Aurora-AAurora-A kinase interacting protein (AIP), a novel negative regulator of human Aurora-A kinaseAurora-A phosphorylates hnRNPK and disrupts its interaction with p53A cancer-associated aurora A mutant is mislocalized and misregulated due to loss of interaction with TPX2Protein phosphatase 6 regulates mitotic spindle formation by controlling the T-loop phosphorylation state of Aurora A bound to its activator TPX2Hec1 sequentially recruits Zwint-1 and ZW10 to kinetochores for faithful chromosome segregation and spindle checkpoint controlThe Schizosaccharomyces pombe aurora-related kinase Ark1 interacts with the inner centromere protein Pic1 and mediates chromosome segregation and cytokinesis.Cloning and characterization of a cDNA encoding an A-kinase anchoring protein located in the centrosome, AKAP450Suppression of the STK15 oncogenic activity requires a transactivation-independent p53 functionCentrosome amplification drives chromosomal instability in breast tumor development.Aurora-A overexpression reveals tetraploidization as a major route to centrosome amplification in p53-/- cellsMitotic phosphorylation of histone H3: spatio-temporal regulation by mammalian Aurora kinasesThe centrosomal kinase Aurora-A/STK15 interacts with a putative tumor suppressor NM23-H1.Characterization of Su48, a centrosome protein essential for cell divisionD-TACC: a novel centrosomal protein required for normal spindle function in the early Drosophila embryoCAS proteins in normal and pathological cell growth controlCentrosomal abnormalities, multipolar mitoses, and chromosomal instability in head and neck tumours with dysfunctional telomeresAssociation of mitotic regulation pathway polymorphisms with pancreatic cancer risk and outcomeCdc20 associates with the kinase aurora2/AikTranscriptional profiling of Krüppel-like factor 4 reveals a function in cell cycle regulation and epithelial differentiationG2E3 is a dual function ubiquitin ligase required for early embryonic developmentLoss of CHFR in human mammary epithelial cells causes genomic instability by disrupting the mitotic spindle assembly checkpointTRIO amplification and abundant mRNA expression is associated with invasive tumor growth and rapid tumor cell proliferation in urinary bladder cancerHuman TPX2 is required for targeting Aurora-A kinase to the spindleMolecular pathology of prostate cancerCharacterization of Cep135, a novel coiled-coil centrosomal protein involved in microtubule organization in mammalian cellsMutations in normal breast tissue and breast tumoursEvolutionary relationships of Aurora kinases: implications for model organism studies and the development of anti-cancer drugsBRCA1: cell cycle checkpoint, genetic instability, DNA damage response and cancer evolutionNon-centrosomal TPX2-Dependent Regulation of the Aurora A Kinase: Functional Implications for Healthy and Pathological Cell Division
P2860
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P2860
Tumour amplified kinase STK15/BTAK induces centrosome amplification, aneuploidy and transformation
description
1998 nî lūn-bûn
@nan
1998 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Tumour amplified kinase STK15/ ...... aneuploidy and transformation
@ast
Tumour amplified kinase STK15/ ...... aneuploidy and transformation
@en
Tumour amplified kinase STK15/ ...... aneuploidy and transformation
@nl
type
label
Tumour amplified kinase STK15/ ...... aneuploidy and transformation
@ast
Tumour amplified kinase STK15/ ...... aneuploidy and transformation
@en
Tumour amplified kinase STK15/ ...... aneuploidy and transformation
@nl
prefLabel
Tumour amplified kinase STK15/ ...... aneuploidy and transformation
@ast
Tumour amplified kinase STK15/ ...... aneuploidy and transformation
@en
Tumour amplified kinase STK15/ ...... aneuploidy and transformation
@nl
P2093
P3181
P356
P1433
P1476
Tumour amplified kinase STK15/ ...... aneuploidy and transformation
@en
P2093
B R Brinkley
P2888
P304
P3181
P356
10.1038/2496
P407
P577
1998-10-01T00:00:00Z
P5875
P6179
1016917923