EWS/Fli-1 chimeric protein is a transcriptional activator
about
EWS, but not EWS-FLI-1, is associated with both TFIID and RNA polymerase II: interactions between two members of the TET family, EWS and hTAFII68, and subunits of TFIID and RNA polymerase II complexes.hTAF(II)68, a novel RNA/ssDNA-binding protein with homology to the pro-oncoproteins TLS/FUS and EWS is associated with both TFIID and RNA polymerase IIEWS-erg and EWS-Fli1 fusion transcripts in Ewing's sarcoma and primitive neuroectodermal tumors with variant translocationsMolecular analysis of the fusion of EWS to an orphan nuclear receptor gene in extraskeletal myxoid chondrosarcomaA developmental switch in the response of DRG neurons to ETS transcription factor signalingTwenty Years on: What Do We Really Know about Ewing Sarcoma and What Is the Path Forward?Ewing sarcoma cells secrete EWS/Fli-1 fusion mRNA via microvesiclesJunction region of EWS-FLI1 fusion protein has a dominant negative effect in Ewing's sarcoma in vitro.Thrombocytopenia in mice lacking the carboxy-terminal regulatory domain of the Ets transcription factor Fli1.Negative and translation termination-dependent positive control of FLI-1 protein synthesis by conserved overlapping 5' upstream open reading frames in Fli-1 mRNA.Identification of a self-association domain in the Ewing's sarcoma protein: a novel function for arginine-glycine-glycine rich motifs?Epigenome mapping reveals distinct modes of gene regulation and widespread enhancer reprogramming by the oncogenic fusion protein EWS-FLI1.Characterization of the genomic breakpoint and chimeric transcripts in the EWS-WT1 gene fusion of desmoplastic small round cell tumorEwing's sarcoma: diagnostic, prognostic, and therapeutic implications of molecular abnormalities.Promiscuous partnerships in Ewing's sarcoma.PI3K/AKT signaling modulates transcriptional expression of EWS/FLI1 through specificity protein 1.Variability of EWS chimaeric transcripts in Ewing tumours: a comparison of clinical and molecular data.Recent advances in the molecular pathogenesis of Ewing's sarcoma.Molecular alterations in pediatric sarcomas: potential targets for immunotherapyEWS/FLI-1 silencing and gene profiling of Ewing cells reveal downstream oncogenic pathways and a crucial role for repression of insulin-like growth factor binding protein 3.EWSR1 binds the hepatitis C virus cis-acting replication element and is required for efficient viral replication.Targeting Lyn inhibits tumor growth and metastasis in Ewing's sarcoma.EWS Knockdown and Taxifolin Treatment Induced Differentiation and Removed DNA Methylation from p53 Promoter to Promote Expression of Puma and Noxa for Apoptosis in Ewing's SarcomaEWS-Fli1 antisense oligodeoxynucleotide inhibits proliferation of human Ewing's sarcoma and primitive neuroectodermal tumor cells.TGF-beta-dependent and -independent roles of STRAP in cancer.Anti-Epileptic Drug Targets Ewing Sarcoma.Detection of EWS/FLI-1 by Immunostaining. An Adjunctive Tool in Diagnosis of Ewing's Sarcoma and Primitive Neuroectodermal Tumour on Cytological Samples and Paraffin-Embedded Archival Material.Progress in the molecular biology of ewing tumors.Relevance of Fusion Genes in Pediatric Cancers: Toward Precision Medicine.Downstream EWS/FLI1 - upstream Ewing's sarcomaPotential molecular targets for Ewing's sarcoma therapy.Transcription factor Fli1 regulates collagen fibrillogenesis in mouse skin.Identification of target genes for the Ewing's sarcoma EWS/FLI fusion protein by representational difference analysis.Structure of noncoding RNA is a determinant of function of RNA binding proteins in transcriptional regulation.Preferential down-regulation of phospholipase C-beta in Ewing's sarcoma cells transfected with antisense EWS-Fli-1.Identification of two types of GGAA-microsatellites and their roles in EWS/FLI binding and gene regulation in Ewing sarcoma.Molecular analysis of Ewing's sarcoma: another fusion gene, EWS-E1AF, available for diagnosis.
P2860
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P2860
EWS/Fli-1 chimeric protein is a transcriptional activator
description
1993 nî lūn-bûn
@nan
1993 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1993 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
name
EWS/Fli-1 chimeric protein is a transcriptional activator
@ast
EWS/Fli-1 chimeric protein is a transcriptional activator
@en
EWS/Fli-1 chimeric protein is a transcriptional activator
@nl
type
label
EWS/Fli-1 chimeric protein is a transcriptional activator
@ast
EWS/Fli-1 chimeric protein is a transcriptional activator
@en
EWS/Fli-1 chimeric protein is a transcriptional activator
@nl
prefLabel
EWS/Fli-1 chimeric protein is a transcriptional activator
@ast
EWS/Fli-1 chimeric protein is a transcriptional activator
@en
EWS/Fli-1 chimeric protein is a transcriptional activator
@nl
P2093
P1433
P1476
EWS/Fli-1 chimeric protein is a transcriptional activator
@en
P2093
P304
P407
P577
1993-12-01T00:00:00Z