Nrf2-Keap1 signaling pathway regulates human UGT1A1 expression in vitro and in transgenic UGT1 mice - Wikidata - wikimedia - TriplyDB

Nrf2-Keap1 signaling pathway regulates human UGT1A1 expression in vitro and in transgenic UGT1 mice

Nrf2-Keap1 signaling pathway regulates human UGT1A1 expression in vitro and in transgenic UGT1 mice

http://www.wikidata.org/entity/Q28285494

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Triclocarban mediates induction of xenobiotic metabolism through activation of the constitutive androstane receptor and the estrogen receptor alpha Overview of AHR functional domains and the classical AHR signaling pathway: induction of drug-metabolizing enzymes Aryl hydrocarbon receptor and NF-E2-related factor 2 are key regulators of human MRP4 expression Cruciferous vegetable feeding alters UGT1A1 activity: diet- and genotype-dependent changes in serum bilirubin in a controlled feeding trial Cancer drug resistance: redox resetting renders a way A perspective on dietary phytochemicals and cancer chemoprevention: oxidative stress, nrf2, and epigenomics Comparison of human Nrf2 antibodies: A tale of two proteins Plants vs. cancer: a review on natural phytochemicals in preventing and treating cancers and their druggability Developmental hyperbilirubinemia and CNS toxicity in mice humanized with the UDP glucuronosyltransferase 1 (UGT1) locus.Use of transgenic mice in UDP-glucuronosyltransferase (UGT) studies Mutual interactions between flavonoids and enzymatic and transporter elements responsible for flavonoid disposition via phase II metabolic pathways.Inhibition of human UGT2B7 gene expression in transgenic mice by the constitutive androstane receptor.Identification of an unintended consequence of Nrf2-directed cytoprotection against a key tobacco carcinogen plus a counteracting chemopreventive intervention.Detoxification: a novel function of BRCA1 in tumor suppression?Effects of combined alcohol and anti-HIV drugs on cellular stress responses in primary hepatocytes and hepatic stellate and kupffer cells Kinetic analyses of Keap1-Nrf2 interaction and determination of the minimal Nrf2 peptide sequence required for Keap1 binding using surface plasmon resonance UDP-glucuronosyltransferase expression in mouse liver is increased in obesity- and fasting-induced steatosis Toll-Like Receptor Signaling Induces Nrf2 Pathway Activation through p62-Triggered Keap1 Degradation.3,4-Dihydroxyphenylacetic acid, a microbiota-derived metabolite of quercetin, attenuates acetaminophen (APAP)-induced liver injury through activation of Nrf-2.Sesamin: A Naturally Occurring Lignan Inhibits CYP3A4 by Antagonizing the Pregnane X Receptor Activation.Major differences among chemopreventive organoselenocompounds in the sustained elevation of cytoprotective genes.Identification of novel NRF2-regulated genes by ChIP-Seq: influence on retinoid X receptor alpha.Xenobiotic-sensing nuclear receptors involved in drug metabolism: a structural perspective Phytochemical regulation of UDP-glucuronosyltransferases: implications for cancer prevention.Expression profiling of interindividual variability following xenobiotic exposures in primary human hepatocyte cultures.LOSS of Mrp1 alters detoxification enzyme expression in a tissue- and hormonal-status-specific manner.Dual roles of Nrf2 in cancer.Pharmacogenetics of Gilbert's syndrome.Coordinate control of expression of Nrf2-modulated genes in the human small airway epithelium is highly responsive to cigarette smoking.Contributions of the Ah receptor to bilirubin homeostasis and its antioxidative and atheroprotective functions.An overview of transcriptional regulation in response to toxicological insult.The generation, detection, and effects of reactive drug metabolites.Nuclear receptors and endobiotics glucuronidation: the good, the bad, and the UGT.A review of the evidence that ochratoxin A is an Nrf2 inhibitor: implications for nephrotoxicity and renal carcinogenicity.Transcriptional regulation of human UDP-glucuronosyltransferase genes.Direct and indirect measurements of enhanced phenolic bioavailability from litchi pericarp procyanidins by Lactobacillus casei-01.Glucose induces intestinal human UDP-glucuronosyltransferase (UGT) 1A1 to prevent neonatal hyperbilirubinemia.Developmental, Genetic, Dietary, and Xenobiotic Influences on Neonatal Hyperbilirubinemia.Selective action of human sera differing in fatty acids and cholesterol content on in vitro gene expression.Regulation of bilirubin clearance by ligand-activated transcription factors of the endo- and xenobiotic metabolism system.

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Nrf2-Keap1 signaling pathway regulates human UGT1A1 expression in vitro and in transgenic UGT1 mice

http://www.wikidata.org/entity/Q28285494

description

2007 nî lūn-bûn

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2007 թուականի Մարտին հրատարակուած գիտական յօդուած

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2007 թվականի մարտին հրատարակված գիտական հոդված

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2007年の論文

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2007年論文

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Nrf2-Keap1 signaling pathway r ...... ro and in transgenic UGT1 mice

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Nrf2-Keap1 signaling pathway r ...... ro and in transgenic UGT1 mice

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Nrf2-Keap1 signaling pathway r ...... ro and in transgenic UGT1 mice

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Nrf2-Keap1 signaling pathway r ...... ro and in transgenic UGT1 mice

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Nrf2-Keap1 signaling pathway r ...... ro and in transgenic UGT1 mice

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Nrf2-Keap1 signaling pathway r ...... ro and in transgenic UGT1 mice

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Nrf2-Keap1 signaling pathway r ...... ro and in transgenic UGT1 mice

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Nrf2-Keap1 signaling pathway r ...... ro and in transgenic UGT1 mice

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Nrf2-Keap1 signaling pathway r ...... ro and in transgenic UGT1 mice

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Journal of Biological Chemistry

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Nrf2-Keap1 signaling pathway r ...... ro and in transgenic UGT1 mice

@en

P2093

Mei-Fei Yueh

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Robert H Tukey

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P2860

Induction of murine NAD(P)H:quinone oxidoreductase by 2,3,7,8-tetrachlorodibenzo-p-dioxin requires the CNC (cap n collar) basic leucine zipper transcription factor Nrf2 (nuclear factor erythroid 2-related factor 2)

BTB protein Keap1 targets antioxidant transcription factor Nrf2 for ubiquitination by the Cullin 3-Roc1 ligase

Isolation of NF-E2-related factor 2 (Nrf2), a NF-E2-like basic leucine zipper transcriptional activator that binds to the tandem NF-E2/AP1 repeat of the beta-globin locus control region

Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain

Control of steroid, heme, and carcinogen metabolism by nuclear pregnane X receptor and constitutive androstane receptor

Human UDP-glucuronosyltransferases: metabolism, expression, and disease

Peroxisome proliferator-activated receptor alpha induces hepatic expression of the human bile acid glucuronidating UDP-glucuronosyltransferase 2B4 enzyme

Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants

Cloning and characterization of the 5'-flanking region of the rat glutamate-cysteine ligase catalytic subunit

Nrf2 is essential for protection against acute pulmonary injury in mice

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8749-58

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scholarly article

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4912450

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10.1074/JBC.M610790200

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12

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282

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2007-03-23T00:00:00Z

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17259171

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