Tyrosine residue 719 of the c-kit receptor is essential for binding of the P85 subunit of phosphatidylinositol (PI) 3-kinase and for c-kit-associated PI 3-kinase activity in COS-1 cells
about
The adapter protein APS associates with the multifunctional docking sites Tyr-568 and Tyr-936 in c-KitControl of Oocyte Reawakening by Kit.Germline mutations of KIT in gastrointestinal stromal tumor (GIST) and mastocytosisKit signaling through PI 3-kinase and Src kinase pathways: an essential role for Rac1 and JNK activation in mast cell proliferationEssential role of the p110beta subunit of phosphoinositide 3-OH kinase in male fertility.C-KIT signaling depends on microphthalmia-associated transcription factor for effects on cell proliferationA human monoclonal antibody targeting the stem cell factor receptor (c-Kit) blocks tumor cell signaling and inhibits tumor growth.Class I(A) PI3Kinase regulatory subunit, p85α, mediates mast cell development through regulation of growth and survival related genesPoint mutation in kit receptor tyrosine kinase reveals essential roles for kit signaling in spermatogenesis and oogenesis without affecting other kit responsesComplex interactions in EML cell stimulation by stem cell factor and IL-3Impact of environmental exposures on ovarian function and role of xenobiotic metabolism during ovotoxicityLipid rafts are required for Kit survival and proliferation signalsSH2 domain-containing phosphatase 2 is a critical regulator of connective tissue mast cell survival and homeostasis in miceRegulation of FOXO3 subcellular localization by Kit ligand in the neonatal mouse ovary.Primordial germ cells and gastrointestinal stromal tumors respond distinctly to a cKit overactivating alleleSignaling of c-kit in dendritic cells influences adaptive immunity.Pharmacological targeting of the KIT growth factor receptor: a therapeutic consideration for mast cell disorders.Emerging functions of c-kit and its ligand stem cell factor in dendritic cells: regulators of T cell differentiationOncogenic mutation in the Kit receptor tyrosine kinase alters substrate specificity and induces degradation of the protein tyrosine phosphatase SHP-1Kit signaling via PI3K promotes ovarian follicle maturation but is dispensable for primordial follicle activationc-kit receptor signaling through its phosphatidylinositide-3'-kinase-binding site and protein kinase C: role in mast cell enhancement of degranulation, adhesion, and membrane ruffling.Differential roles of PI3-kinase and Kit tyrosine 821 in Kit receptor-mediated proliferation, survival and cell adhesion in mast cells.The stem cell factor (SCF)/c-KIT signalling in testis and prostate cancer.Autoinhibition of the kit receptor tyrosine kinase by the cytosolic juxtamembrane region.The D816V mutation of c-Kit circumvents a requirement for Src family kinases in c-Kit signal transduction.Targeted disruption of SHIP leads to Steel factor-induced degranulation of mast cells.C-Kit Promotes Growth and Migration of Human Cardiac Progenitor Cells via the PI3K-AKT and MEK-ERK Pathways.Imatinib upregulates compensatory integrin signaling in a mouse model of gastrointestinal stromal tumor and is more effective when combined with dasatinib.Direct interaction between Kit and the interleukin-7 receptor.Protein-tyrosine phosphatase alpha regulates stem cell factor-dependent c-Kit activation and migration of mast cells.Direct engagement of the PI3K pathway by mutant KIT dominates oncogenic signaling in gastrointestinal stromal tumor.Autophosphorylation of KIT
P2860
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P2860
Tyrosine residue 719 of the c-kit receptor is essential for binding of the P85 subunit of phosphatidylinositol (PI) 3-kinase and for c-kit-associated PI 3-kinase activity in COS-1 cells
description
1994 nî lūn-bûn
@nan
1994 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1994 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
name
Tyrosine residue 719 of the c- ...... kinase activity in COS-1 cells
@ast
Tyrosine residue 719 of the c- ...... kinase activity in COS-1 cells
@en
Tyrosine residue 719 of the c- ...... kinase activity in COS-1 cells
@nl
type
label
Tyrosine residue 719 of the c- ...... kinase activity in COS-1 cells
@ast
Tyrosine residue 719 of the c- ...... kinase activity in COS-1 cells
@en
Tyrosine residue 719 of the c- ...... kinase activity in COS-1 cells
@nl
prefLabel
Tyrosine residue 719 of the c- ...... kinase activity in COS-1 cells
@ast
Tyrosine residue 719 of the c- ...... kinase activity in COS-1 cells
@en
Tyrosine residue 719 of the c- ...... kinase activity in COS-1 cells
@nl
P2093
P3181
P1476
Tyrosine residue 719 of the c- ...... kinase activity in COS-1 cells
@en
P2093
P304
P3181
P407
P577
1994-02-25T00:00:00Z