Essential role of the p110beta subunit of phosphoinositide 3-OH kinase in male fertility.
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Phosphoinositides: tiny lipids with giant impact on cell regulationStructure of Lipid Kinase p110β/p85β Elucidates an Unusual SH2-Domain-Mediated Inhibitory MechanismThe p110α and p110β isoforms of PI3K play divergent roles in mammary gland development and tumorigenesis.Spermiation: The process of sperm releaseNovel Role for p110β PI 3-Kinase in Male Fertility through Regulation of Androgen Receptor Activity in Sertoli CellsRAS and RHO families of GTPases directly regulate distinct phosphoinositide 3-kinase isoforms.PI3K isoform dependence of PTEN-deficient tumors can be altered by the genetic context.A constitutively activated form of the p110beta isoform of PI3-kinase induces prostatic intraepithelial neoplasia in mice.PI3K in cancer: divergent roles of isoforms, modes of activation and therapeutic targeting.Fgf9 inhibition of meiotic differentiation in spermatogonia is mediated by Erk-dependent activation of Nodal-Smad2/3 signaling and is antagonized by Kit Ligand.Comparative Transcriptome Analysis of Differentially Expressed Genes and Signaling Pathways between XY and YY Testis in Yellow Catfish.Dispensable role of PTEN in mouse spermatogenesisSpatially distinct roles of class Ia PI3K isoforms in the development and maintenance of PTEN hamartoma tumor syndrome.Role of phosphatase of regenerating liver 1 (PRL1) in spermatogenesis.The gene dosage of class Ia PI3K dictates the development of PTEN hamartoma tumor syndrome.Phosphatase of regenerating liver 2 (PRL2) deficiency impairs Kit signaling and spermatogenesis.G protein-coupled receptor-mediated activation of p110β by Gβγ is required for cellular transformation and invasiveness.Loss of PI3K p110α in the Adipose Tissue Results in Infertility and Delayed Puberty Onset in Male Mice.PI-3 kinase p110β: a therapeutic target in advanced prostate cancers.PI3King the right partner: unique interactions and signaling by p110β.Integrated analysis of mRNA-seq and miRNA-seq reveals the potential roles of sex-biased miRNA-mRNA pairs in gonad tissue of dark sleeper (Odontobutis potamophila).D-Aspartate Induces Proliferative Pathways in Spermatogonial GC-1 Cells.Small copy-number variations involving genes of the FGF pathway in differences in sex development.Coincident signals from GPCRs and receptor tyrosine kinases are uniquely transduced by PI3Kβ in myeloid cells.Combined inhibition of PI3Kβ and PI3Kγ reduces fat mass by enhancing α-MSH-dependent sympathetic drive.Rac1-stimulated macropinocytosis enhances Gβγ activation of PI3Kβ.MGAT1 and Complex N-Glycans Regulate ERK Signaling During Spermatogenesis.Inhibition of mTOR pathway decreases the expression of pre-meiotic and meiotic markers throughout postnatal development and in adult testes in mice.Leucine mediates autophagosome-lysosome fusion and improves sperm motility by activating the PI3K/Akt pathway.
P2860
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P2860
Essential role of the p110beta subunit of phosphoinositide 3-OH kinase in male fertility.
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2010 nî lūn-bûn
@nan
2010 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2010年の論文
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2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
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name
Essential role of the p110beta subunit of phosphoinositide 3-OH kinase in male fertility.
@ast
Essential role of the p110beta subunit of phosphoinositide 3-OH kinase in male fertility.
@en
type
label
Essential role of the p110beta subunit of phosphoinositide 3-OH kinase in male fertility.
@ast
Essential role of the p110beta subunit of phosphoinositide 3-OH kinase in male fertility.
@en
prefLabel
Essential role of the p110beta subunit of phosphoinositide 3-OH kinase in male fertility.
@ast
Essential role of the p110beta subunit of phosphoinositide 3-OH kinase in male fertility.
@en
P2093
P2860
P50
P356
P1476
Essential role of the p110beta subunit of phosphoinositide 3-OH kinase in male fertility
@en
P2093
Fiorella Altruda
Frieder Wolf
Giovanni Sorba
Giulio Mengozzi
Kaomei Guan
Pier Paolo Pandolfi
Xiaoyun Lu
P2860
P304
P356
10.1091/MBC.E09-08-0744
P577
2010-01-06T00:00:00Z